Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mark R. Hardy"'
Autor:
TroyZ Richards, Mark R. Hardy, Steve Koza, Deb Ellis, Martin S. Sinacore, Scott Harrison, Linda Francullo, Monique Davies, Richard J. Cornell, Amy Woodard
Publikováno v:
Animal Cell Technology: Products from Cells, Cells as Products ISBN: 9780792360759
P-Selectin Glycoprotein Ligand-1 (PSGL-1) is a dimeric mucin-like transmembrane glycoprotein identified as a functional ligand for P-Selectin (1). Functional activity of PSGL-1 is dependent upon at least two key posttranslational modifications made t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2223568cd10288dedfb2b46a6a80f3f
https://doi.org/10.1007/0-306-46875-1_53
https://doi.org/10.1007/0-306-46875-1_53
Autor:
Mark R. Hardy, Robert J. Cotter, Yuan C. Lee, R.Reid Townsend, Catherine Fenselau, Richard C. Simpson
Publikováno v:
Analytical Chemistry. 62:248-252
An interface is described that allows the direct coupling of high-performance alkaline anion exchange liquid chromatography with thermospray mass spectrometry. A membrane suppressor is used to remove nonvolatile alkaline salts from the mobile phase a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357724e8a2078423032abf9ff9d1b1c9
https://doi.org/10.1021/ac00202a005
https://doi.org/10.1021/ac00202a005
Autor:
Richard J. Cornell, Mark R. Hardy
Publikováno v:
Carbohydrate-Based Drug Discovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::007715844285a7f22518a0e40fb46893
https://doi.org/10.1002/3527602437.ch19
https://doi.org/10.1002/3527602437.ch19
Publikováno v:
Journal of pharmaceutical sciences. 83(12)
Characterization of monoclonal antibodies (MAbs) produced for therapeutic or diagnostic purposes increasingly includes an assessment of their carbohydrate content. Using high-performance anion exchange chromatography with pulsed amperometric detectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2341231b4682a0c143dc103ea6e5def
https://pubmed.ncbi.nlm.nih.gov/7891293
https://pubmed.ncbi.nlm.nih.gov/7891293
Autor:
Mark R. Hardy, Raymond R. Townsend
Publisher Summary This chapter discusses the basic high-pH anion-exchange chromatography (HPAEC) methods for monosaccharide and oligosaccharide analysis of glycoproteins and a sample preparation approach that extends these methods to the analysis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::42f257472b62e100d0ddc966f67b0e8d
https://doi.org/10.1016/0076-6879(94)30014-3
https://doi.org/10.1016/0076-6879(94)30014-3
Autor:
Mark R. Hardy, Raymond R. Townsend
Publikováno v:
Glycobiology. 1(2)
The natural heterogeneity of glycoprotein glycans requires that chromatography be an essential part of structural elucidation. The isomeric nature of oligosaccharide structure requires chromatography which is selective for not only composition, size
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595fc6e8eb01057339c89e1f55bfd6da
https://pubmed.ncbi.nlm.nih.gov/1823157
https://pubmed.ncbi.nlm.nih.gov/1823157
Autor:
Michael Weitzhandler, Mark R. Hardy
Publikováno v:
Journal of chromatography. 510
A dot blotting assay using digoxigenin hydrazide (Glycan detection kit, Boehringer Mannheim Biochemicals) was used to screen an endoproteinase Lys-C peptide map of ribonuclease B for the presence of glycopeptides. The carbohydrate content of the iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c106d6eb69eb6505b8a4639d2583337
https://pubmed.ncbi.nlm.nih.gov/2205615
https://pubmed.ncbi.nlm.nih.gov/2205615
Publikováno v:
Biochemical Society Transactions. 23:103S-103S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61fc29124ca82f34c56752d74bea5da3
https://doi.org/10.1042/bst023103s
https://doi.org/10.1042/bst023103s
Publikováno v:
Analytical Biochemistry. 135:392-400
Treatment of agarose beads with mild acid (0.2 m HCl, 55°C, several hours) hydrolyzes some of the glycosidic bonds between d -galactosyl residues and 3,6-anhydro- l -galactosyl residues, and thus produces aldehydo-groups useful for immobilization of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ce4ecc6e27561bfde280e5a55d8178
https://doi.org/10.1016/0003-2697(83)90701-7
https://doi.org/10.1016/0003-2697(83)90701-7