Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mark R. Addley"'
Autor:
Mark R. Addley, Nigel J. Stevenson, Caroline R. Boyd, Verica Paunovic, Wilson A. Coulter, Keith M. Channon, Christina A. Bursill, James A. Johnston, Marilyn A. Armstrong, Angela McClurg, Elizabeth J. Ryan, David R. Greaves, Helen P. Carroll, Helen C. Miller
The chemokine eotaxin/CCL11 is an important mediator of leukocyte migration, but its effect on inflammatory cytokine signaling has not been explored. In this study, we find that CCL11 induces suppressor of cytokine signaling (SOCS)1 and SOCS3 express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bd459e67825e681bc3561e2e854cc39
https://doi.org/10.1189/jlb.0708394
https://doi.org/10.1189/jlb.0708394
Autor:
Carmel M. Quinn, Siamon Gordon, Mark R. Addley, Andrew J. McKnight, Alison J. Macfarlane, David R. Greaves, Dawn O'Reilly
Publikováno v:
Genomics. 84:1030-1040
This study has investigated the transcriptional regulation of the Emr1 gene in murine macrophages and defined an enhancer element within the proximal promoter that is necessary for Emr1 expression in myeloid cells. This element consists of an extende
Publikováno v:
Journal of Virology. 78:6263-6270
Replication of the influenza A virus virion RNA (vRNA) requires the synthesis of full-length cRNA, which in turn is used as a template for the synthesis of more vRNA. A “corkscrew” secondary-structure model of the cRNA promoter has been proposed
Publikováno v:
Journal of Molecular Histology
Treatment of cells with cytokines and growth factors leads to the synthesis of Suppressor of Cytokine Signalling (SOCS) proteins that act as potent negative regulators of signalling via the Jak/STAT pathway. We used immunohistochemistry to identify c
Autor:
Nigel J. Stevenson, Cheryl McFarlane, Alyson A. Kelvin, Mark R. Addley, James A. Johnston, Cliona O'Farrelly, Krystyna Nahlik, David R. Greaves, Seow Theng Ong, Aideen Long
Publikováno v:
FEBS letters. 584(21)
Suppressors of cytokine signalling (SOCS) proteins regulate signal transduction, but their role in responses to chemokines remains poorly understood. We report that cells expressing SOCS1 and 3 exhibit enhanced adhesion and reduced migration towards