Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Mark R Spaller"'
Autor:
Santanu Bhattacharya, Krishnendu Pal, Anil K Sharma, Shamit K Dutta, Julie S Lau, Irene K Yan, Enfeng Wang, Ahmed Elkhanany, Khalid M Alkharfy, Arunik Sanyal, Tushar C Patel, Suresh T Chari, Mark R Spaller, Debabrata Mukhopadhyay
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114409 (2014)
GAIP interacting protein C terminus (GIPC) is known to play an important role in a variety of physiological and disease states. In the present study, we have identified a novel role for GIPC as a master regulator of autophagy and the exocytotic pathw
Externí odkaz:
https://doaj.org/article/09280cc855094a579ee67ad2cb4917df
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103650 (2014)
PDZ domains are protein-protein interaction modules that coordinate multiple signaling and trafficking pathways in the cell and that include active therapeutic targets for diseases such as cancer, cystic fibrosis, and addiction. Our previous work cha
Externí odkaz:
https://doaj.org/article/6c4920efa01548feb47511f22800aca3
Autor:
Cong Cao, Mengia S Rioult-Pedotti, Paolo Migani, Crystal J Yu, Rakesh Tiwari, Keykavous Parang, Mark R Spaller, Dennis J Goebel, John Marshall
Publikováno v:
PLoS Biology, Vol 11, Iss 2, p e1001478 (2013)
Angelman syndrome (AS) is a neurodevelopment disorder characterized by severe cognitive impairment and a high rate of autism. AS is caused by disrupted neuronal expression of the maternally inherited Ube3A ubiquitin protein ligase, required for the p
Externí odkaz:
https://doaj.org/article/77acc942576c417da7ed2d208bb31be3
Autor:
Debabrata Mukhopadhyay, Mark R. Spaller, Shantanu Chowdhury, Khalid M. Alkharfy, Soundararajan Krishnaswamy, Suruchi Aggarwal, Vinod Kumar Yadav, Aradhita Baral, Ruizhi Zhao, Enfeng Wang, Shamit K. Dutta, Alexandre A. Pletnev, Krishnendu Pal
Supplementary Figure 2: CD31 and HandE staining of tumor tissue sections obtained from AP1063-treated and AP1032-treated groups.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e861e8524aad7b6a0b2e6c01ae085a
https://doi.org/10.1158/1535-7163.22502862.v1
https://doi.org/10.1158/1535-7163.22502862.v1
Autor:
Debabrata Mukhopadhyay, Mark R. Spaller, Shantanu Chowdhury, Khalid M. Alkharfy, Soundararajan Krishnaswamy, Suruchi Aggarwal, Vinod Kumar Yadav, Aradhita Baral, Ruizhi Zhao, Enfeng Wang, Shamit K. Dutta, Alexandre A. Pletnev, Krishnendu Pal
Detailed procedure for the synthesis of lipidated peptides.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9114a734e994c3c2fcb6d45ec98c806c
https://doi.org/10.1158/1535-7163.22502859
https://doi.org/10.1158/1535-7163.22502859
Autor:
Debabrata Mukhopadhyay, Mark R. Spaller, Shantanu Chowdhury, Khalid M. Alkharfy, Soundararajan Krishnaswamy, Suruchi Aggarwal, Vinod Kumar Yadav, Aradhita Baral, Ruizhi Zhao, Enfeng Wang, Shamit K. Dutta, Alexandre A. Pletnev, Krishnendu Pal
Supplementary Figure 1: CD31 and HandE staining of tumor tissue sections obtained from control and Endoglin shRNA treated cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d970153b3253ddb8a528b2400c5aac4
https://doi.org/10.1158/1535-7163.22502865
https://doi.org/10.1158/1535-7163.22502865
Autor:
Enfeng Wang, Debabrata Mukhopadhyay, Vijay Sagar Madamsetty, Yan W. Asmann, Thomas R. Caulfield, Shamit K. Dutta, Alexandre A. Pletnev, Mark R Spaller, David K. Chang, Rosanna Upstill-Goddard, Sneha Vivekanandhan, Ramcharan Singh Angom
Publikováno v:
Cancers
Volume 13
Issue 16
Cancers, Vol 13, Iss 4048, p 4048 (2021)
Volume 13
Issue 16
Cancers, Vol 13, Iss 4048, p 4048 (2021)
Simple Summary Pancreatic cancer is among the most lethal cancers. The expression of PLEXIND1, a receptor, is upregulated in many cancers (including pancreatic cancer). Traditionally, PLEXIND1 is known to be involved in neuron development and mediate
Autor:
Gregory J. Tsongalis, Mark R. Spaller, Megan E. Romano, Suyapa Bejarano, Zhongze Li, Karen L. Huyck, Mark A Cervinski, Thomas G. Flynn, Kathleen Doyle Lyons, Charlene M. Dunaway, Linda S. Kennedy, Ethan P. M. LaRochelle
Publikováno v:
International journal of hygiene and environmental health. 234
Background Occupational exposure to agrochemicals, some of which are known or suspected carcinogens, is a major health hazard for subsistence agricultural workers and their families. These impacts are more prevalent in low-and-middle income countries
Autor:
Anton Omelchenko, Joshua A. Roshal, Heidi M Chapman, Harita Menon, Tiffany L. Wang, Gaurav Kumar, Eduardo R. Martinez-Montes, Sarah G. Donofrio, Bonnie L. Firestein, Mark R. Spaller
Publikováno v:
Mol Neurobiol
CRIPT, the cysteine-rich PDZ-binding protein, binds to the third PDZ domain of PSD-95 (postsynaptic density protein 95) family proteins and directly binds microtubules, linking PSD-95 family proteins to the neuronal cytoskeleton. Here, we show that o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9b570b7dd8b40d7061c1e8501001a2a
https://europepmc.org/articles/PMC7176523/
https://europepmc.org/articles/PMC7176523/
Autor:
Nashaat Z. Gerges, Erik B. Faber, Inmaculada Pereda-Pérez, Mark R. Spaller, Randy A. Hall, Jose Viña, Liping Mou, Lara Ordóñez-Gutiérrez, José A. Esteban, Cristina Sánchez-Puelles, Rafael Pulido, Andrew K Chan, Tina Wahle, Manuel Serrano, Janire Mingo, Heidi M Chapman, Francisco Wandosell, Ana Ortega-Molina, Shira Knafo, Kanwardeep Kaleka, Jonathan E. Draffin, Laura Lozano-Montes, Igotz Delgado, Edvin Klosi, César Venero, Ernest Palomer, Carlos G. Dotti
Publikováno v:
NATURE NEUROSCIENCE
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
r-INCLIVA. Repositorio Institucional de Producción Científica de INCLIVA
instname
Dyshomeostasis of amyloid-β peptide (Aβ) is responsible for synaptic malfunctions leading to cognitive deficits ranging from mild impairment to full-blown dementia in Alzheimer's disease. Aβ appears to skew synaptic plasticity events toward depres