Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Mark R Perry"'
Autor:
Marcellene A Gates-Hollingsworth, Mark R Perry, Hongjing Chen, James Needham, Raymond L Houghton, Syamal Raychaudhuri, Mark A Hubbard, Thomas R Kozel
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0126304 (2015)
Inhalational anthrax is a serious biothreat. Effective antibiotic treatment of inhalational anthrax requires early diagnosis; the further the disease has progressed, the less the likelihood for cure. Current means for diagnosis such as blood culture
Externí odkaz:
https://doaj.org/article/f8260738de6f423aa0d6209979f4f24b
Autor:
Meisam Naeimi Kararoudi, Alfahdah Alsudayri, Cynthia L. Hill, Ezgi Elmas, Yasemin Sezgin, Aarohi Thakkar, Mark E. Hester, Daniel T. Malleske, Dean A. Lee, Matthew L. Neal, Mark R. Perry, Jill A. Harvilchuck, Susan D. Reynolds
Publikováno v:
Frontiers in Genome Editing, Vol 4 (2022)
Respiratory system damage is the primary cause of mortality in individuals who are exposed to vesicating agents including sulfur mustard (SM). Despite these devastating health complications, there are no fielded therapeutics that are specific for suc
Externí odkaz:
https://doaj.org/article/6111819b0f364180ad5dd6f223c4f700
Autor:
Meisam Naeimi Kararoudi, Alfahdah Alsudayri, Cynthia L. Hill, Ezgi Elmas, Yasemin Sezgin, Aarohi Thakkar, Mark E. Hester, Daniel T. Malleske, Dean A. Lee, Matthew L. Neal, Mark R. Perry, Jill A. Harvilchuck, Susan D. Reynolds
Publikováno v:
Frontiers in Genome Editing, Vol 4 (2022)
Respiratory system damage is the primary cause of mortality in individuals who are exposed to vesicating agents including sulfur mustard (SM). Despite these devastating health complications, there are no fielded therapeutics that are specific for suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::582f8b79481854ba52c1ef9c585f9058
https://pubmed.ncbi.nlm.nih.gov/35199100
https://pubmed.ncbi.nlm.nih.gov/35199100
Autor:
Roger Hawks, Cheryl A. Triplett, Meredith Andrews, David T. Pressburger, Michael S. Nealy, Jan Satola, Jill A. Harvilchuck, Gennady E. Platoff, Matthew Neal, David T. Yeung, Mark R. Perry, Beth A. Reed
Publikováno v:
Inhal Toxicol
OBJECTIVE: To develop a novel inhalation exposure system capable of delivering a controlled inhaled HD dose through an endotracheal tube to anesthetized rats to investigate the lung pathophysiology and evaluate potential medical countermeasures. MATE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0671f688f569b6b6bdd5bc9251420844
https://pubmed.ncbi.nlm.nih.gov/34396872
https://pubmed.ncbi.nlm.nih.gov/34396872
Autor:
Jeffry D. Shearer, Joshua J. Reece, Laurence Lemiale, Vladimir Savransky, Roy E. Barnewall, Boris Ionin, Mario H. Skiadopoulos, Michelle L. Vassar, Mark R. Perry, Sukjoon Park
Publikováno v:
Vaccine
A next-generation anthrax vaccine candidate, AV7909, is being developed for post-exposure prophylaxis (PEP) of inhalational anthrax in combination with the recommended course of antimicrobial therapy. Clinical efficacy studies of anthrax countermeasu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125ed03c4c1cfb0b86dc9e04006f1af4
https://europepmc.org/articles/PMC8905666/
https://europepmc.org/articles/PMC8905666/
Autor:
M. Claire Matthews, Matthew K. Brittain, Mark R. Perry, Jillian M. Staugler, Michael C. Babin
Publikováno v:
Inhalation Toxicology. 30:195-202
Cyanide is a highly toxic chemical, and acute exposure depletes cells and tissue of oxygen, depressing the respiratory, cardiovascular and neurological systems and potentially leading to death. Cyanide has been used as a weapon since ancient Rome and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d01cb9bd98b4f59233e58a5f7bb7ec52
https://doi.org/10.1080/08958378.2018.1494764
https://doi.org/10.1080/08958378.2018.1494764
Cyanides are highly toxic compounds that have been used as weapons of terrorism throughout history. Cyanide (CN) is acutely toxic by all routes of administration; however, inhalation is the main exposure route. To adequately test effective countermea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e8af03dde6ecda46e90a0c0c02c92df
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology
The elimination of smallpox as an endemic disease and the obvious ethical problems with clinical challenge requires the efficacy evaluation of medical countermeasures against smallpox using the FDA Animal Rule. This approach requires the evaluation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::649957bf8494cc2e57b33c47586b22a4
https://www.frontiersin.org/article/10.3389/fcimb.2018.00356/full
https://www.frontiersin.org/article/10.3389/fcimb.2018.00356/full
Autor:
Michael C. Babin, David T. Yeung, Jennifer L. Plahovinsak, Jonathon W. Kohne, Gennady E. Platoff, Eric Benson, Mark R. Perry
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 71:120-128
Introduction A custom designed HD exposure system was used to deliver controlled inhaled doses to an animal model through an endotracheal tube. Methods Target HD vapor challenges were generated by a temperature controlled bubbler/aerosol trap, while
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f45eec7d3fb15c5b89a6cffcb816741
https://doi.org/10.1016/j.vascn.2014.09.009
https://doi.org/10.1016/j.vascn.2014.09.009
Autor:
Jennifer L. Plahovinsak, John S. Graham, Mark R. Perry, Frances M. Reid, James V. Rogers, William R. Richter, Thomas H. Snider
Publikováno v:
Cutaneous and Ocular Toxicology. 33:161-167
Assessing the hazards of accidental exposure to toxic industrial chemical (TIC) vapors and evaluating therapeutic compounds or treatment regimens require the development of appropriate animal models.The objective of this project was to develop an exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d0d71b859f37275961717830c13fa9c
https://doi.org/10.3109/15569527.2013.806524
https://doi.org/10.3109/15569527.2013.806524