Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mark R, MacRae"'
Autor:
Nicolas Coudray, Georgia L Isom, Mark R MacRae, Mariyah N Saiduddin, Gira Bhabha, Damian C Ekiert
Publikováno v:
eLife, Vol 9 (2020)
In double-membraned bacteria, phospholipid transport across the cell envelope is critical to maintain the outer membrane barrier, which plays a key role in virulence and antibiotic resistance. An MCE transport system called Mla has been implicated in
Externí odkaz:
https://doaj.org/article/4016616d4aad4d58a6b5047540cc998d
Autor:
Ljuvica R Kolich, Ya-Ting Chang, Nicolas Coudray, Sabrina I Giacometti, Mark R MacRae, Georgia L Isom, Evelyn M Teran, Gira Bhabha, Damian C Ekiert
Publikováno v:
eLife, Vol 9 (2020)
ABC transporters facilitate the movement of diverse molecules across cellular membranes, but how their activity is regulated post-translationally is not well understood. Here we report the crystal structure of MlaFB from E. coli, the cytoplasmic port
Externí odkaz:
https://doaj.org/article/3537baf37d634cd1915f09b00ac02461
Autor:
Sabrina I, Giacometti, Mark R, MacRae, Kristen, Dancel-Manning, Gira, Bhabha, Damian C, Ekiert
Publikováno v:
Annual Review of Cell and Developmental Biology. 38:125-153
The movement of lipids within and between membranes in bacteria is essential for building and maintaining the bacterial cell envelope. Moving lipids to their final destination is often energetically unfavorable and does not readily occur spontaneousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f73e0a6f7fbf5e50b4d34512ffbb700
https://doi.org/10.1146/annurev-cellbio-120420-022914
https://doi.org/10.1146/annurev-cellbio-120420-022914
Autor:
Mark R. MacRae, Dhenesh Puvanendran, Max A. B. Haase, Nicolas Coudray, Ljuvica Kolich, Cherry Lam, Minkyung Baek, Gira Bhabha, Damian C. Ekiert
Publikováno v:
Journal of Biological Chemistry. 299:104744
The outer membrane (OM) of Gram-negative bacteria is an asymmetric bilayer that protects the cell from various external stressors, such as antibiotics. The Mla transport system is implicated in theMaintenance of outer membraneLipidAsymmetry and is th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d91c7415367e2edb58cdc65f26563d
https://doi.org/10.1016/j.jbc.2023.104744
https://doi.org/10.1016/j.jbc.2023.104744
Autor:
Mariyah N. Saiduddin, Gira Bhabha, Georgia L. Isom, Damian C. Ekiert, Mark R. MacRae, Nicolas Coudray
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
In double-membraned bacteria, phospholipids must be transported across the cell envelope to maintain the outer membrane barrier, which plays a key role in antibiotic resistance and pathogen virulence. The Mla system has been implicated in phospholipi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98f7952e3aef03a3a7cad569f8a7491f
https://elifesciences.org/articles/62518
https://elifesciences.org/articles/62518
Autor:
Damian C. Ekiert, Mark R. MacRae, Sabrina I Giacometti, Ya-Ting Chang, Nicolas Coudray, Ljuvica Kolich, Georgia L. Isom, Gira Bhabha, Evelyn M Teran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24d25cb806d55d74d02ae0efb7666569
https://doi.org/10.7554/elife.60030.sa2
https://doi.org/10.7554/elife.60030.sa2
Autor:
Ya-Ting Chang, Georgia L. Isom, Mark R. MacRae, Gira Bhabha, Damian C. Ekiert, Sabrina I Giacometti, Evelyn M Teran, Nicolas Coudray, Ljuvica Kolich
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
ABC transporters facilitate the movement of a diverse array of molecules across cellular membranes, using power from ATP hydrolysis. While the overall mechanism of the transport cycle has been characterized in detail for several important members of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019f1fe70e23e8c38b7647bb03e4e156
Autor:
Nicolas Coudray, Mark R. MacRae, Gira Bhabha, Rachel L. Redler, Damian C. Ekiert, Georgia L. Isom
Publikováno v:
Microscopy and Microanalysis. 27:1422-1422
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a2a658b71b8f6f875b40e5c8999cc4c
https://doi.org/10.1017/s1431927621005262
https://doi.org/10.1017/s1431927621005262
Autor:
Mark R. MacRae, Gira Bhabha, Damian C. Ekiert, Nicolas Coudray, Collin T. McManus, Georgia L. Isom
Publikováno v:
SSRN Electronic Journal.
Gram-negative bacteria are surrounded by an outer membrane composed of phospholipids and lipopolysaccharide (LPS), which acts as a barrier to the environment and contributes to antibiotic resistance. While mechanisms of LPS transport have been well c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56d4011afbc473148a53efef80c274f5
https://doi.org/10.2139/ssrn.3469836
https://doi.org/10.2139/ssrn.3469836