Výsledky vyhledávání - "Mark R, Haussler"

Akademický článek

Vitamin D Receptor Mediates a Myriad of Biological Actions Dependent on Its 1,25‐Dihydroxyvitamin D Ligand: Distinct Regulatory Themes Revealed by Induction of Klotho and Fibroblast Growth Factor‐23

Autor: Mark R Haussler, Sarah Livingston, Zhela L Sabir, Carol A Haussler, Peter W Jurutka

Publikováno v: JBMR Plus, Vol 5, Iss 1, Pp n/a-n/a (2021)

ABSTRACT The hormonal vitamin D metabolite, 1,25‐dihydroxyvitamin D [1,25(OH)2D], produced in kidney, acts in numerous end organs via the nuclear vitamin D receptor (VDR) to trigger molecular events that orchestrate bone mineral homeostasis. VDR is

Externí odkaz: https://doaj.org/article/c7425342a9a941979042901e2ad20917

Zobrazit plný text záznamu

Akademický článek

Pomegranate derivative urolithin A enhances vitamin D receptor signaling to amplify serotonin-related gene induction by 1,25-dihydroxyvitamin D

Autor: Sarah Livingston, Sanchita Mallick, Daniel A. Lucas, Marya S. Sabir, Zhela L. Sabir, Hespera Purdin, Sree Nidamanuri, Carol A. Haussler, Mark R. Haussler, Peter W. Jurutka

Publikováno v: Biochemistry and Biophysics Reports, Vol 24, Iss , Pp 100825- (2020)

Mediated by the nuclear vitamin D receptor (VDR), the hormonally active vitamin D metabolite, 1,25-dihydroxyvitamin D3 (1,25D), is known to regulate expression of genes impacting calcium and phosphorus metabolism, the immune system, and behavior. Uro

Externí odkaz: https://doaj.org/article/97eedda4d71a409f88143dc9029b252a

Zobrazit plný text záznamu

Akademický článek

Optimal vitamin D spurs serotonin: 1,25-dihydroxyvitamin D represses serotonin reuptake transport (SERT) and degradation (MAO-A) gene expression in cultured rat serotonergic neuronal cell lines

Autor: Marya S. Sabir, Mark R. Haussler, Sanchita Mallick, Ichiro Kaneko, Daniel A. Lucas, Carol A. Haussler, G. Kerr Whitfield, Peter W. Jurutka

Publikováno v: Genes & Nutrition, Vol 13, Iss 1, Pp 1-11 (2018)

Abstract Background Diminished brain levels of two neurohormones, 5-hydroxytryptamine (5-HT; serotonin) and 1,25-dihydroxyvitamin D3 (1,25D; active vitamin D metabolite), are proposed to play a role in the atypical social behaviors associated with ps

Externí odkaz: https://doaj.org/article/e504b2f50ce6418ba2ba5000d168baf8

Zobrazit plný text záznamu

Autor: Peter W. Jurutka, Zhela L. Sabir, Carol A. Haussler, Mark R. Haussler, Sarah Livingston

Publikováno v: JBMR Plus, Vol 5, Iss 1, Pp n/a-n/a (2021)
JBMR Plus

The hormonal vitamin D metabolite, 1,25‐dihydroxyvitamin D [1,25(OH)2D], produced in kidney, acts in numerous end organs via the nuclear vitamin D receptor (VDR) to trigger molecular events that orchestrate bone mineral homeostasis. VDR is a ligand

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb9f546650404b70b1444fe8475c3b72
https://doaj.org/article/c7425342a9a941979042901e2ad20917

Zobrazit plný text záznamu

Pomegranate derivative urolithin A enhances vitamin D receptor signaling to amplify serotonin-related gene induction by 1,25-dihydroxyvitamin D

Autor: Mark R. Haussler, Sree Nidamanuri, Carol A. Haussler, Sanchita Mallick, Zhela L. Sabir, Hespera Purdin, Daniel A. Lucas, Peter W. Jurutka, Sarah Livingston, Marya S. Sabir

Publikováno v: Biochemistry and Biophysics Reports, Vol 24, Iss, Pp 100825-(2020)
Biochemistry and Biophysics Reports

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95fcd1fe84364bfd7d2d1191307b4c7c
https://pubmed.ncbi.nlm.nih.gov/33088927

Zobrazit plný text záznamu

SIRT1 enzymatically potentiates 1,25-dihydroxyvitamin D3 signaling via vitamin D receptor deacetylation

Autor: G. Kerr Whitfield, Zainab Khan, Elizabeth T. Jacobs, Sanchita Mallick, Marya S. Sabir, Christopher M. Dussik, Angelika Dampf Stone, Chengcheng Hu, Michael C. Heck, Michael A. Galligan, Shane F. Batie, Mark R. Haussler, Peter W. Jurutka

Publikováno v: The Journal of Steroid Biochemistry and Molecular Biology. 172:117-129

The hormonal metabolite of vitamin D, 1,25-dihydroxyvitamin D3 (1,25D), binds to the vitamin D receptor (VDR) and promotes heterodimerization of VDR with a retinoid-X-receptor (RXR) to genomically regulate diverse cellular processes. Herein, it is re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e0f272924a4e181aff1b826e22bebfbb
https://doi.org/10.1016/j.jsbmb.2017.06.010

Zobrazit plný text záznamu

Association between Circulating Vitamin D Metabolites and Fecal Bile Acid Concentrations

Autor: David S. Alberts, Elizabeth T. Jacobs, Denise J. Roe, Lindsay N. Kohler, Mark R. Haussler, Peter W. Jurutka, Peter Lance, Maria Elena Martinez

Publikováno v: Cancer Prevention Research. 9:589-597

Although hydrophobic bile acids have been demonstrated to exhibit cytotoxic and carcinogenic effects in the colorectum, ursodeoxycholic acid (UDCA) has been investigated as a potential chemopreventive agent. Vitamin D has been shown to play a role in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b38874091af5b4d5ba60296098bec696
https://doi.org/10.1158/1940-6207.capr-16-0033

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání