Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Mark Plumb"'
Autor:
Mark Plumb, Peter Bain
Essential Tremor is the most common movement disorder in the world, and affects between 4 and 40 people per 1000 of the population amongst all ethnic groups. Characterised by shaking hands, this disorder can affect the head, voice and legs, and is of
Autor:
Mark Plumb, Abigail Zanker, Christopher J. Talbot, Mays Jawad, Simon Fitch, Clare Cole, George Giotopoulos
Publikováno v:
Mammalian Genome. 19:190-198
Differences in the number of functionally and/or phenotypically defined bone marrow cells in inbred mouse strains have been exploited to map quantitative trait loci (QTL) that determine the variation in cell frequency. To extend this approach to the
Autor:
R. P. Symonds, K Foweraker, Irene M Peat, M Griffin, Mark Plumb, George Giotopoulos, Ahmed Osman
Publikováno v:
British Journal of Cancer
The relationship between late normal tissue radiation injury phenotypes in 167 breast cancer patients treated with radiotherapy and: (i) radiotherapy dose (boost); (ii) an early acute radiation reaction and (iii) genetic background was examined. Pati
Publikováno v:
International Journal of Radiation Biology. 82:383-391
To investigate the influence of genetic and epigenetic factors on allelic loss on chromosomes 2 and 4 in mouse radiation-induced acute myeloid leukaemia (r-AML).r-AML that arose in (CBA/HxC57BL/6)F1xCBA/H and F1xC57BL/6 mice were screened for transcr
Autor:
Mark Plumb
Publikováno v:
International Journal of Radiation Biology. 79:367-370
Autor:
Yuri E. Dubrova, Mark Plumb
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 499:143-150
The analysis of the effects of ionising radiation on germline mutations is limited by the number of offspring that need to be analysed following exposure to a dose, which is relevant to risk assessment in humans. We have developed a new experimental
Publikováno v:
Blood. 98:1549-1554
The CBA/H mouse model of radiation-induced acute myeloid leukemia (AML) was re-examined using molecular approaches. In addition to the typical promyelocytic AMLs, 34% were reclassified as early pre-B lympho-myeloid leukemias (L-ML) based on leukemic
Publikováno v:
International Journal of Radiation Biology. 77:21-29
To determine whether there is a relationship between the genetics underlying the susceptibility to radiation-induced leukaemia in CBA/H (acute myeloid leukaemia, AML) and C57BL/6 (thymic lymphoma, TL) mice, and the genetics underlying the sensitivity
Autor:
Emma Boulton, Andrew G. Smith, Yuri E. Dubrova, Mark Plumb, Ruth C. Barber, Alec J. Jeffreys, Carolina E. Cesar
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 457:79-91
To test the hypothesis that mouse germline expanded simple tandem repeat (ESTR) mutations are associated with recombination events during spermatogenesis, crossover frequencies were compared with germline mutation rates at ESTR loci in male mice acut