Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mark Phong"'
Autor:
Beng Ti Ang, Carol Tang, Ivan Ng, Wai Hoe Ng, Greg Tucker-Kellogg, Oi Lian Kon, Siew Hong Leong, Swee Seong Wong, Mark Phong, Edwin Sandanaraj, Geraldene Rong-Hui Koh, Esther Hui-Ling Ting, Tan Boon Toh, Felicia Soo-Lee Ng
PDF file - 688K, Supplementary Fig. S1. NNI-8 GPCs display stemness expression and extensive self-renewal.Supplementary Fig. S2. NNI-8 orthotopic xenograft recapitulates patient tumor pathophysiology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::703b30891d9d2694cbe9d4c67ee4df2d
https://doi.org/10.1158/1078-0432.22443275.v1
https://doi.org/10.1158/1078-0432.22443275.v1
Autor:
Beng Ti Ang, Carol Tang, Ivan Ng, Wai Hoe Ng, Greg Tucker-Kellogg, Oi Lian Kon, Siew Hong Leong, Swee Seong Wong, Mark Phong, Edwin Sandanaraj, Geraldene Rong-Hui Koh, Esther Hui-Ling Ting, Tan Boon Toh, Felicia Soo-Lee Ng
Purpose: Patient-derived glioma-propagating cells (GPC) contain karyotypic and gene expression profiles that are found in the primary tumor. However, their clinical relevance is unclear. We ask whether GPCs contribute to disease progression and survi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a37b35ff8e93d27a56a4853cc92c65ad
https://doi.org/10.1158/1078-0432.c.6519749
https://doi.org/10.1158/1078-0432.c.6519749
Autor:
Yuk Kien Chong, Ivan Ng, Edwin Sandanaraj, Marie-Veronique Clement, Geraldene Rong-Hui Koh, Beng Ti Ang, Wai Hoe Ng, Shazib Pervaiz, Oi Lian Kon, Lynnette Koh, Greg Tucker-Kellogg, Tan Boon Toh, Carol Tang, Felicia Soo Lee Ng, Mark Phong
Publikováno v:
Antioxidants & Redox Signaling. 19:2261-2279
We explore the role of an elevated O2(-):H2O2 ratio as a prosurvival signal in glioma-propagating cells (GPCs). We hypothesize that depleting this ratio sensitizes GPCs to apoptotic triggers.We observed that an elevated O2(-):H2O2 ratio conferred enh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e1efa183768232826fa8ce2779206d
https://doi.org/10.1089/ars.2012.4999
https://doi.org/10.1089/ars.2012.4999
Autor:
Siew Hong Leong, Mark Phong, Felicia Soo Lee Ng, Ivan Ng, Swee Seong Wong, Carol Tang, Oi Lian Kon, Esther Hui-Ling Ting, Edwin Sandanaraj, Tan Boon Toh, Beng Ti Ang, Geraldene Rong-Hui Koh, Wai Hoe Ng, Greg Tucker-Kellogg
Publikováno v:
Clinical Cancer Research. 18:4122-4135
Purpose: Patient-derived glioma-propagating cells (GPC) contain karyotypic and gene expression profiles that are found in the primary tumor. However, their clinical relevance is unclear. We ask whether GPCs contribute to disease progression and survi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea8c0df2f5d5172df141fc8cc67e6f5b
https://doi.org/10.1158/1078-0432.ccr-11-3064
https://doi.org/10.1158/1078-0432.ccr-11-3064
Autor:
Beng Ti Ang, Charlene Shu Fen Foong, Yuk Kien Chong, Robert M. Campbell, Mark Phong, Greg Tucker-Kellogg, Tan Boon Toh, Felicia Soo Lee Ng, Carol Tang
Publikováno v:
Frontiers in bioscience (Scholar edition). 3(2)
Glioblastoma multiforme (GBM) represents the most devastating adult brain tumor. GBM follows a hierarchical development in oncogenesis, with a sub-population of cells - brain tumor stem cells (BTSCs), exhibiting tumor-initiating potential. BTSCs poss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c72381f70c7003029e7296900f78cf37
https://pubmed.ncbi.nlm.nih.gov/21196406
https://pubmed.ncbi.nlm.nih.gov/21196406
Publikováno v:
Molecular and cellular biology. 30(15)
p38 mitogen-activated protein kinase (MAPK) was originally identified as a 38-kDa protein that undergoes rapid tyrosine phosphorylation in response to stress (17). Significant progress has been made in the past decade to understand the p38 signal tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb8db6122d35bed871f20939e765f02
https://pubmed.ncbi.nlm.nih.gov/20516219
https://pubmed.ncbi.nlm.nih.gov/20516219
Autor:
Leslie Brail, Boris Lin, Susan Sutton, Michael Lahn, Mark Phong, Birong Liao, Donald Thornton, Shuyu Li
Publikováno v:
Biology Direct
Biology Direct, Vol 2, Iss 1, p 8 (2007)
Biology Direct, Vol 2, Iss 1, p 8 (2007)
Background Both mechanistic features and recent correlative findings suggest a potential role for protein kinase C-beta (PKC-β) in tumor pathogenesis, particularly in B-cell malignancies. To evaluate the role of this gene in lymphoid malignancies, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2576a71ae3c336ac0183f3de711a22d
https://pubmed.ncbi.nlm.nih.gov/17313671
https://pubmed.ncbi.nlm.nih.gov/17313671
Publikováno v:
Cancer Research. 70:4863-4863
NSD-1 (Nuclear receptor-binding SET domain protein 1) belongs to the epigenetic family of histone methyltransferases (HMTs), which are frequently found to be mutated in overgrowth syndromes. In cancer, NSD-1 is found as part of fusion proteins (e.g.,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::383603dd0162f5bc32c2191afb5a7459
https://doi.org/10.1158/1538-7445.am10-4863
https://doi.org/10.1158/1538-7445.am10-4863