Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Mark Philips"'
Autor:
David Liang, Liping Jiang, Sameer Ahmed Bhat, Sonia Missiroli, Mariasole Perrone, Angela Lauriola, Ritika Adhikari, Anish Gudur, Zahra Vasi, Ian Ahearn, Daniele Guardavaccaro, Carlotta Giorgi, Mark Philips, Shafi Kuchay
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111999- (2023)
Summary: Substrate degradation by the ubiquitin proteasome system (UPS) in specific membrane compartments remains elusive. Here, we show that the interplay of two lipid modifications and PDE6δ regulates compartmental substrate targeting via the SCFF
Externí odkaz:
https://doaj.org/article/d663d5a395244e3bab84b46f3f717660
Autor:
Wei-Ching Chen, Minh D. To, Peter M. K. Westcott, Reyno Delrosario, Il-Jin Kim, Mark Philips, Quan Tran, Saumya R. Bollam, Hani Goodarzi, Nora Bayani, Olga Mirzoeva, Allan Balmain
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Kras is frequently mutated in lung cancer and two isoforms are generated via alternative splicing. Here, the authors show that the two isoforms have divergent roles in cancer stem cells and the main tumour cell population, which are regulated by hypo
Externí odkaz:
https://doaj.org/article/a22b5d5de40945018011a5128be0357a
Agpat6—a novel lipid biosynthetic gene required for triacylglycerol production in mammary epithelium
Autor:
Anne P. Beigneux, Laurent Vergnes, Xin Qiao, Steven Quatela, Ryan Davis, Steven M. Watkins, Rosalind A. Coleman, Rosemary L. Walzem, Mark Philips, Karen Reue, Stephen G. Young
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 4, Pp 734-744 (2006)
In analyzing the sequence tags for mutant mouse embryonic stem (ES) cell lines in BayGenomics (a mouse gene-trapping resource), we identified a novel gene, 1-acylglycerol-3-phosphate O-acyltransferase (Agpat6), with sequence similarities to previousl
Externí odkaz:
https://doaj.org/article/f47c93497a0d44c39f6d0111b289aad1
Autor:
Kevin M. Haigis, David B. Solit, Mark Philips, Channing J. Der, James M. Bugni, Jessica Gierut, Gerald C. Chu, Adam J. Bass, Shouyong Peng, Efsevia Vakiani, Sérgia Velho, Yufang Wang
Supplementary Figure S3 PDF file 66K,Additional data related to the proliferative and apoptotic phenotypes of CRC cells expressing mutant Ras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1944ab43e95e00de6e3eb39c7c552d
https://doi.org/10.1158/2159-8290.22530590
https://doi.org/10.1158/2159-8290.22530590
Autor:
Kevin M. Haigis, David B. Solit, Mark Philips, Channing J. Der, James M. Bugni, Jessica Gierut, Gerald C. Chu, Adam J. Bass, Shouyong Peng, Efsevia Vakiani, Sérgia Velho, Yufang Wang
Supplementary Figure Legends PDF file 72K, Legends for Supplementary Figures 1-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c16078b4de56035cb8e2965a547dd63
https://doi.org/10.1158/2159-8290.22530599.v1
https://doi.org/10.1158/2159-8290.22530599.v1
Autor:
Kevin M. Haigis, David B. Solit, Mark Philips, Channing J. Der, James M. Bugni, Jessica Gierut, Gerald C. Chu, Adam J. Bass, Shouyong Peng, Efsevia Vakiani, Sérgia Velho, Yufang Wang
Supplementary Tables 1 and 2 PDF file 91K, Table 1 contains clinical and genotypic data from the patient cohort referred to in Fig. 6. Table 2 contains shRNA target sequences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90a292b3f3f7482d1d060ada9b3e8f5
https://doi.org/10.1158/2159-8290.22530575
https://doi.org/10.1158/2159-8290.22530575
Autor:
Mark Philips, Antonio García-España
KRAS, HRAS and NRAS oncogenes belong to a family of 40 highly homologous genes, which in turn are a subset of a superfamily of >160 genes encoding small GTPases. RAS oncoproteins consist of a globular G-domain (aa1-166) and a 22-23aa unstructured hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::133e0d674759e413ab95abb8ce1dfcb0
https://doi.org/10.21203/rs.3.rs-2485219/v1
https://doi.org/10.21203/rs.3.rs-2485219/v1
Autor:
Michael Evans, Mark Philips
Publikováno v:
State, Resistance and Change in South Africa ISBN: 9781003308362
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e676ca12df35ac4bb5f2ecfdb15172b8
https://doi.org/10.4324/9781003308362-5
https://doi.org/10.4324/9781003308362-5
Autor:
Gabrielle Gardiner, Kirsty Kitto, Simon Buckingham Shum, Moein Ghodrati, Julieanne Cutrupi, Mark Philips
Publikováno v:
Higher Education and the Future of Graduate Employability ISBN: 9781788972611
This book challenges the dominant ‘employability skills’ discourse by exploring socially connected and networked perspectives to learning and teaching in higher education.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::838de9930c9b15c3b17b8cbc02b34357
https://hdl.handle.net/10453/137484
https://hdl.handle.net/10453/137484
Publikováno v:
Transfusion. 59(1)