Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Mark Pezzano"'
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83024 (2013)
Thymic microenvironments are essential for the proper development and selection of T cells critical for a functional and self-tolerant adaptive immune response. While significant turnover occurs, it is unclear whether populations of adult stem cells
Externí odkaz:
https://doaj.org/article/ee1124e72b5249a19e877d5010a1aed2
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9062 (2010)
Thymic epithelial cell (TEC) microenvironments are essential for the recruitment of T cell precursors from the bone marrow, as well as the subsequent expansion and selection of thymocytes resulting in a mature self-tolerant T cell repertoire. The mol
Externí odkaz:
https://doaj.org/article/0a7a10b5575a4e8c98b505736dcd53ad
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8675 (2010)
A complete understanding of negative selection has been elusive due to the rapid apoptosis and clearance of thymocytes in vivo. We report a TCR transgenic model in which expression of the TCR during differentiation occurs only after V(D)J-like recomb
Externí odkaz:
https://doaj.org/article/24ea7fcdeded467db479f5656282a528
Autor:
Jae E. Lee, Emma Fernández-Repollet, Shafiq A. Kahn, Andrew Dent, Latrice Rollins, Noreen Mokuau, M. Edwina Barnett, Jaydutt V. Vadgama, Tabia Henry Akintobi, Maria F. Lima, Vincent C. Bond, Daniel F. Sarpong, Marla J. Berry, Keith C. Norris, Mark Pezzano, Paul B. Tchounwou, Carlos A. Luciano, Elizabeth Ofili, Richard Yanagihara, Angela Sy, Deepak Kumar, Mohamad Malouhi, Clayton Yates, Marcia Cruz-Correa, Adebayo Oyekan, Jerris R. Hedges, Brenda Y. Hernandez, Muna Abdelrahim, Richard J. Noel, Karam F.A. Soliman, Traci Hayes, Pamela L. Bullard, Solomon T. Garner, George Perry, Sandra P. Chang, Bruce Shiramizu, Almelida R. Baker, Robert A. Kirken
Publikováno v:
Ethnicity & Disease. 29:135-144
The Research Centers in Minority Institutions (RCMI) program was established by the US Congress to support the development of biomedical research infrastructure at minority-serving institutions granting doctoral degrees in the health professions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06d19f1171e44b6a1ae5fd889c7f1d7
https://doi.org/10.18865/ed.29.s1.135
https://doi.org/10.18865/ed.29.s1.135
Autor:
Nawshin Zara Jamil, Varan J. Singh, Mohammed Hoque, Neelab Meer, Mark Pezzano, Shami Chakrabarti
In paradox to critical functions for T-cell selection and self-tolerance, the thymus undergoes profound age-associated atrophy and loss of T-cell function, which are further enhanced by cancer therapies. Identification of thymic epithelial progenitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3b04bb1bf2168503f2a27942a426aee2
https://doi.org/10.1101/2020.09.29.319426
https://doi.org/10.1101/2020.09.29.319426
Autor:
Hector A. Fermin, Mark Pezzano, Masako Osada, Emi Ito, Roland H. Friedel, Tadmiri Venkatesh, Edwin Vazquez-Cintron
Publikováno v:
Clinical and Developmental Immunology
Clinical and Developmental Immunology, Vol 13, Iss 2-4, Pp 299-319 (2006)
Clinical and Developmental Immunology, Vol 13, Iss 2-4, Pp 299-319 (2006)
Wnt signaling has been reported to regulate thymocyte proliferation and selection at several stages during T cell ontogeny, as well as the expression ofFoxN1in thymic epithelial cells (TECs). Kremen1 (Krm1) is a negative regulator of the canonical Wn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf3c94542420d44a63be485a6e79d757
http://europepmc.org/articles/PMC2270768
http://europepmc.org/articles/PMC2270768
Publikováno v:
ResearcherID
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3149484b6ea857c6add587d24ea19813
https://doi.org/10.1096/fasebj.28.1_supplement.lb546
https://doi.org/10.1096/fasebj.28.1_supplement.lb546
Publikováno v:
Microbiology and Molecular Biology Reviews. 65:390-403
SUMMARYSince their discovery in 1980, thymic nurse cells (TNCs) have been controversial. Questions pertaining to the existence of the TNC as a “unit” cell with thymocytes completely enclosed within its cytoplasm were the focus of initial debates.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c46b91a374d6d4b4f5e32f071dd10f
https://doi.org/10.1128/mmbr.65.3.390-403.2001
https://doi.org/10.1128/mmbr.65.3.390-403.2001
Autor:
Jerry C. Guyden, William Boto, K. J. Park, J. Riley, S.-K. Lee, G. A. Pestano, Mark Pezzano, Michael Samms, A. S. Hasan
Publikováno v:
Archives of Virology. 145:2087-2103
The results of the study presented in this report show that clones of env derived from genetically divergent HIV-1 field isolates fall into two major subsets based on the predicted secondary structure of the V3 region in gp120. One subset exemplified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2394d199ebae213f422a151d5ba42105
https://doi.org/10.1007/s007050070041
https://doi.org/10.1007/s007050070041
Autor:
Jun Yang, Adebowale Adeyemi, William Boto, Karen D. King, Jerry C. Guyden, Deborah Philp, Mark Pezzano, Birdette Gardiner, Michael Samms
Publikováno v:
Cellular Immunology. 185:123-133
A thymic epithelial cell line (tsTNC-1) that maintains the ability to selectively bind and internalize immature alpha beta TCRloCD4+CD8+ thymocytes in vitro was used in the development of a monoclonal antibody that is specific to the cell surface of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06769b7a630f0e49b752f65b6bad320b
https://doi.org/10.1006/cimm.1998.1279
https://doi.org/10.1006/cimm.1998.1279