Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Mark Perelis"'
Autor:
Biliana Marcheva, Benjamin J Weidemann, Akihiko Taguchi, Mark Perelis, Kathryn Moynihan Ramsey, Marsha V Newman, Yumiko Kobayashi, Chiaki Omura, Jocelyn E Manning Fox, Haopeng Lin, Patrick E Macdonald, Joseph Bass
Publikováno v:
eLife, Vol 11 (2022)
The mammalian circadian clock drives daily oscillations in physiology and behavior through an autoregulatory transcription feedback loop present in central and peripheral cells. Ablation of the core clock within the endocrine pancreas of adult animal
Externí odkaz:
https://doaj.org/article/4ba877e38361469da7c8d4a16351a710
Autor:
Tim Nicholson-Shaw, Yasmeen Ajaj, Mark Perelis, Amit Fulzele, Gene W. Yeo, Eric J. Bennett, Jens Lykke-Andersen
SummaryThe Ribosome-associated Quality Control (RQC) pathway serves to resolve ribosomes stalled during the translation process and degrade the associated mRNA and nascent polypeptide. Here we identify the 2’,3’ cyclic phosphatase Angel1 as a rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84f16ae857698221e79ee0563105aca4
https://doi.org/10.1101/2022.04.28.489582
https://doi.org/10.1101/2022.04.28.489582
Autor:
Akihiko Taguchi, Biliana Marcheva, Gene W. Yeo, Emily C. Wheeler, Patrick E. MacDonald, Chiaki Omura, Marsha V. Newman, Yumiko Kobayashi, Eugene Wyatt, Mark Perelis, Archana Shankar, Jocelyn E. Manning Fox, Elizabeth M. McNally, Hee Kyung Hong, Benjamin J. Weidemann, Haopeng Lin, Kathryn Moynihan Ramsey, Joseph Bass
Publikováno v:
Genes Dev
The circadian clock is encoded by a negative transcriptional feedback loop that coordinates physiology and behavior through molecular programs that remain incompletely understood. Here, we reveal rhythmic genome-wide alternative splicing (AS) of pre-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b4eb5d12e23aa7ee90970e13a53dc3e
https://doi.org/10.1101/gad.338178.120
https://doi.org/10.1101/gad.338178.120
Autor:
Akihiko Taguchi, Benjamin J Weidemann, Biliana Marcheva, Mark Perelis, Kathryn Moynihan Ramsey, Marsha V Newman, Yumiko Kobayashi, Chiaki Omura, Jocelyn E Manning Fox, Haopeng Lin, Patrick E Macdonald, Joseph Bass
Publikováno v:
eLife. 11
The mammalian circadian clock drives daily oscillations in physiology and behavior through an autoregulatory transcription feedback loop present in central and peripheral cells. Ablation of the core clock within the endocrine pancreas of adult animal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d30b13fae1eaa175938486eef4728238
https://doi.org/10.7554/elife.75132
https://doi.org/10.7554/elife.75132
Autor:
Akihiko Taguchi, Benjamin J Weidemann, Biliana Marcheva, Mark Perelis, Kathryn Moynihan Ramsey, Marsha V Newman, Yumiko Kobayashi, Chiaki Omura, Jocelyn E Manning Fox, Haopeng Lin, Patrick E Macdonald, Joseph Bass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7aec5310739666020ed9c6ccb1d225f
https://doi.org/10.7554/elife.75132.sa2
https://doi.org/10.7554/elife.75132.sa2
Autor:
Rosellina M. Mancina, Kavitha Sasidharan, Anna Lindblom, Ying Wei, Ester Ciociola, Oveis Jamialahmadi, Piero Pingitore, Anne-Christine Andréasson, Giovanni Pellegrini, Guido Baselli, Ville Männistö, Jussi Pihlajamäki, Vesa Kärjä, Stefania Grimaudo, Ilaria Marini, Marco Maggioni, Barbara Becattini, Federica Tavaglione, Carly Dix, Marie Castaldo, Stephanie Klein, Mark Perelis, Francois Pattou, Dorothée Thuillier, Violeta Raverdy, Paola Dongiovanni, Anna Ludovica Fracanzani, Felix Stickel, Jochen Hampe, Stephan Buch, Panu K. Luukkonen, Daniele Prati, Hannele Yki-Järvinen, Salvatore Petta, Chao Xing, Clemens Schafmayer, Elmar Aigner, Christian Datz, Richard G. Lee, Luca Valenti, Daniel Lindén, Stefano Romeo
Publikováno v:
Nature Metabolism
Fatty liver disease (FLD) is a growing health issue with burdening unmet clinical needs. FLD has a genetic component but, despite the common variants already identified, there is still a missing heritability component. Using a candidate gene approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a0b9e69fd26eeaf0a14faf2dcce3a2b
http://hdl.handle.net/10447/533875
http://hdl.handle.net/10447/533875
Autor:
Patrick E. MacDonald, Marsha V. Newman, Akihiko Taguchi, Biliana Marcheva, Chiaki Omura, Haopeng Lin, Mark Perelis, Jocelyn E. Manning Fox, Kathryn Moynihan Ramsey, Benjamin J. Weidemann, Yumiko Kobayashi, Joseph Bass
SummaryThe mammalian circadian clock drives daily oscillations in physiology and behavior through an autoregulatory transcription feedback loop present in central and peripheral cells. Ablation of the core clock within the endocrine pancreas of adult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db1cb98dbd6462ab87532bb4ae21773d
https://doi.org/10.1101/2021.11.05.467499
https://doi.org/10.1101/2021.11.05.467499
Autor:
Biliana Marcheva, Mark Perelis, Benjamin J. Weidemann, Akihiko Taguchi, Haopeng Lin, Chiaki Omura, Yumiko Kobayashi, Marsha V. Newman, Eugene J. Wyatt, Elizabeth M. McNally, Jocelyn E. Manning Fox, Heekyung Hong, Archana Shankar, Emily C. Wheeler, Kathryn Moynihan Ramsey, Patrick E. MacDonald, Gene W. Yeo, Joseph Bass
Publikováno v:
Genes Dev
The circadian clock is encoded by a negative transcriptional feedback loop that coordinates physiology and behavior through molecular programs that remain incompletely understood. Here, we reveal rhythmic genome-wide alternative splicing (AS) of pre-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebc86b4fe0f524395c227fb3eec6da4
https://pubmed.ncbi.nlm.nih.gov/32616519
https://pubmed.ncbi.nlm.nih.gov/32616519
Autor:
Roland Stein, Mark Perelis, Joseph Bass, Holly A. Cyphert, Shuangli Guo, Yu-Ping Yang, Jin Hua Liu, Mark A. Magnuson, Christopher V.E. Wright, Jason M. Spaeth, Min Guo, Manisha Gupte
Publikováno v:
Diabetes. 66:2830-2839
The transcription factor encoded by the Pdx1 gene is a critical transcriptional regulator, as it has fundamental actions in the formation of all pancreatic cell types, islet β-cell development, and adult islet β-cell function. Transgenic- and cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3afce2331e066e43c4d6b2d0ba9b2dcb
https://doi.org/10.2337/db16-1516
https://doi.org/10.2337/db16-1516
Publikováno v:
SSRN Electronic Journal.
In plants, Cryptochromes are photoreceptors that negatively regulate CRL4Cop1 (Cul4-RING ubiquitin ligase and its substrate receptor Cop1). In mammals, Cryptochromes are core components of the circadian clock and repressors of the glucocorticoid rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12c710040fff53ef8888f977c94f3908
https://doi.org/10.2139/ssrn.3334427
https://doi.org/10.2139/ssrn.3334427