Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Mark P. Watterson"'
1
Mannuronolactone acetonide: easy access to C-3 OH and C-5 OH of mannose
Autor: Thomas Martin Krulle, Juan C. Estévez, Mark P. Watterson, Angeles Martín, George W. J. Fleet
The synthesis of d -mannuronolactone acetonide 1 is described from alginic acid and provides an efficient route for the manipulation at C-5 of mannose. Reduction gives a new acetonide of mannose, 1,2-O- isopropylidene-β- d -mannofuranose which, on f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920a9eef442f4f16b480795f186e530f
https://ora.ox.ac.uk/objects/uuid:c4e724e8-08ec-4290-a933-85c9a0bba1e7
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2
Synthesis of all diastereomeric methyl 2,5-anhydro-3-deoxy-hexonates: precursors to C-2-deoxynucleosides and THF-templated gamma- and delta-amino acids
Autor: Alison A. Edwards, John A. Leach, Martin D. Smith, Mark P. Watterson, George W. J. Fleet, Osamu Ichihara
Publikováno v: Tetrahedron Letters
Efficient syntheses of all diastereomers of methyl 2,5-anhydro-3-deoxy-hexonate from mannono- or gulono-lactones provide precursors for C-nucleosides of 2-deoxyribose and for THF-templated γ- and δ-amino acids. © 2003 Elsevier Ltd. All rights rese
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df13cffcde567b5c1955f1352b2783fd
https://doi.org/10.1016/s0040-4039(03)01416-3
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3
Isopropyl 2,5-anhydro-6-azido-3,6-dideoxy-D-xylo-hexonate
Autor: David J. Watkin, Alison A. Edwards, George E. Tranter, George W. J. Fleet, Mark P. Watterson
Determination of the crystal structure of the title isopropyl azido ester, C9H15N3O4, confirmed its relative stereochemistry and validated further work on the use of a derived sugar amino acid (SAA) as a peptidomimetic.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8aa741a08eab968ca194342f3e83e77d
https://ora.ox.ac.uk/objects/uuid:9ad66ba0-7c8b-47c6-b07f-730a0c232e3b
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4
Templated scaffolds of cis- and trans-tetrahydrofuran gamma-amino acids: gamma-azido-beta-hydroxy-tetrahydrofuran-2-carboxylates from pentono-delta-lactones
Autor: George W. J. Fleet, Alistair Stewart, Mark P. Watterson, Raquel Gonzalez, Shuji Hachisu, Gangadharar J. Sanjayan
Short syntheses of enantiomeric templated scaffolds of cis- and trans-tetrahydrofuran γ-amino acids from pentono-δ-lactones derived from arabinose and ribose are reported; an unexpectedly efficient synthesis of a templated tetrahydrofuran β-amino
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86c270526a45f7c0949af0234ffbe30d
https://ora.ox.ac.uk/objects/uuid:08f7ea8c-51f5-4c01-a6ee-1555974a94ba
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7
cis- and trans-3-Azido-oxetane-2-carboxylate scaffolds: hexamers of oxetane cis-β-amino acids
Autor: Mark P. Watterson, Michael R. Probert, George W. J. Fleet, Donald Angus, Claude Taillefumier, Timothy D. W. Claridge, David J. Watkin, Sarah F. Barker, Natasha L. Hungerford
Publikováno v: Tetrahedron Letters. 42:4247-4250
Efficient synthesis of both cis- and trans-3-azido-oxetane-2-carboxylates relies upon efficient nucleophilic displacements of 3-O-triflates of oxetanes by trifluoroacetate and azide. Such structures are scaffolds for incorporation of oxetane-β-amino
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21d10b7f442ca2505772567be44b3041
https://doi.org/10.1016/s0040-4039(01)00660-8
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