Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Mark P. Bowes"'
Autor:
Joshua A. Zeichner, Mark P. Bowes
Publikováno v:
Psoriasis Forum. :2-7
Vitamin D receptor modulators have been used extensively for years in the treatment of psoriasis. These agents have demonstrated comparable efficacy to mid-potency corticosteroids and have a good safety profile. Vitamin D receptor modulators are usef
Publikováno v:
Brain Research. 883:178-183
Continuous intracerebroventricular or intrathecal infusions of neurotrophic factors have been reported to prevent neuronal degeneration, stimulate axonal sprouting and ameliorate behavioral deficits in various models of CNS injury and aging. In the p
Publikováno v:
Experimental Neurology. 141:40-46
Hemorrhagic transformation (HT) is a poorly understood yet frequent complication of stroke. A transient increase in blood pressure (BP) occurs immediately after experimental embolization in rabbits and we evaluated the relationship between this acute
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 16:967-972
Glutamate (Glu) neurotoxicity is an important element of a number of neurological disorders including central nervous system (CNS) ischemia. We evaluated the effects of the novel AMPA Glu antagonist LY293558 on functional neurological outcome in two
Publikováno v:
Stroke. 25:2253-2257
Hemodilution using modified hemoglobin solutions may reduce ischemic central nervous system injury. Purified diaspirin cross-linked hemoglobin (DCLHb) is a cell-free hemoglobin that is intramolecularly cross-linked between the two alpha subunits, res
Publikováno v:
Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 8(6)
Background: With the implementation of thrombolysis, a large number of distinct pharmacological agents are now under consideration for the treatment of acute ischemic stroke, with disappoiting early results. Because the processes that ultimately lead
Publikováno v:
Experimental neurology. 150(1)
We examined the relationship between acute hypertension following cerebral embolization and subsequent hemorrhagic transformation (HT) in a rabbit embolic stroke model. We have shown previously that the likelihood and severity of hemorrhage were sign
Publikováno v:
Neurology. 45(4)
We evaluated the ability of monoclonal antibodies directed against leukocyte adhesion molecules (intercellular adhesion molecule-1 [ICAM-1], CD18) to enhance the efficacy of thrombolysis in a rabbit cerebral embolism stroke model. Both tissue-type pl
Publikováno v:
Experimental neurology. 129(1)
Although found as a precursor of Alzheimer amyloid, substantial evidence suggests that β/A4 protein precursor (APP) is involved in regulation of neuronal growth and survival. Recently, we have obtained evidence that the trophic properties of APP are
Publikováno v:
Experimental neurology. 119(2)
We evaluated the effect of antibodies directed against a leukocyte adhesion molecule (ICAM-1) in an embolic model of stroke followed by thrombolysis with tissue plasminogen activator (tPA). To test whether reperfusion injury after ischemia was relate