Zobrazeno 1 - 10
of 272
pro vyhledávání: '"Mark P Lewis"'
Publikováno v:
Journal of Tissue Engineering, Vol 14 (2023)
Extracellular vesicles (EVs) continue to gain interest across the scientific community for diagnostic and therapeutic applications. As EV applications diversify, it is essential that researchers are aware of challenges, in particular the compatibilit
Externí odkaz:
https://doaj.org/article/042f60092479461c8f4f48c34486381c
Publikováno v:
Journal of Tissue Engineering, Vol 11 (2020)
Herein, the cytotoxicity of a novel zwitterionic sulfobetaine hydrogel system with a nano-clay crosslinker has been investigated. We demonstrate that careful selection of the composition of the system (monomer to Laponite content) allows the material
Externí odkaz:
https://doaj.org/article/a6d7669b6d444879824e71a80c6963e8
Variant-proof high affinity ACE2 antagonist limits SARS-CoV-2 replication in upper and lower airways
Autor:
Matthew Gagne, Barbara J. Flynn, Christopher Cole Honeycutt, Dillon R. Flebbe, Shayne F. Andrew, Samantha J. Provost, Lauren McCormick, Alex Van Ry, Elizabeth McCarthy, John-Paul M. Todd, Saran Bao, I-Ting Teng, Shir Marciano, Yinon Rudich, Chunlin Li, Shilpi Jain, Bushra Wali, Laurent Pessaint, Alan Dodson, Anthony Cook, Mark G. Lewis, Hanne Andersen, Jiří Zahradník, Mehul S. Suthar, Martha C. Nason, Kathryn E. Foulds, Peter D. Kwong, Mario Roederer, Gideon Schreiber, Robert A. Seder, Daniel C. Douek
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract SARS-CoV-2 has the capacity to evolve mutations that escape vaccine- and infection-acquired immunity and antiviral drugs. A variant-agnostic therapeutic agent that protects against severe disease without putting selective pressure on the vir
Externí odkaz:
https://doaj.org/article/398a2dfd9ac6483f881f1a81f6f17840
Publikováno v:
Journal of Tissue Engineering, Vol 7 (2016)
Mechanical loading is recognized to play an important role in regulating the behaviors of cells in bone and surrounding tissues in vivo. Many in vitro studies have been conducted to determine the effects of mechanical loading on individual cell types
Externí odkaz:
https://doaj.org/article/6a2445d2761a4c6182abc95aa6c88280
Autor:
María Fernández‐Rhodes, Emma Buchan, Stephanie D. Gagnon, Jiani Qian, Lee Gethings, Rebecca Lees, Ben Peacock, Andrew J. Capel, Neil R. W. Martin, Pola Goldberg Oppenheimer, Mark P. Lewis, Owen G. Davies
Publikováno v:
Journal of Extracellular Biology, Vol 3, Iss 8, Pp n/a-n/a (2024)
Abstract Skeletal muscle (SM) acts as a secretory organ, capable of releasing myokines and extracellular vesicles (SM‐EVs) that impact myogenesis and homeostasis. While age‐related changes have been previously reported in murine SM‐EVs, no stud
Externí odkaz:
https://doaj.org/article/25f03d8b84794b319851e03ae9786910
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
IntroductionSuccessful vaccine promotion communication strategies require knowing how eligible recipients will respond to the opportunity to get vaccinated. Two main classes of recipients are myopic rationalists, those who receive a dose of vaccine o
Externí odkaz:
https://doaj.org/article/6a104ad50aef4253b29d7b35f6c17862
Autor:
Bradley J. Wilkes, Derek B. Archer, Anna L. Farmer, Carly Bass, Hannah Korah, David E. Vaillancourt, Mark H. Lewis
Publikováno v:
Molecular Autism, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Background Restricted repetitive behavior (RRB) is one of two behavioral domains required for the diagnosis of autism spectrum disorder (ASD). Neuroimaging is widely used to study brain alterations associated with ASD and the domain of socia
Externí odkaz:
https://doaj.org/article/ac5c0a1944614263acc36b28b25a0e7d
Autor:
Peter R. Thompson, Peter D. Harrington, Conor D. Mallory, Subhash R. Lele, Erin M. Bayne, Andrew E. Derocher, Mark A. Edwards, Mitch Campbell, Mark A. Lewis
Publikováno v:
Movement Ecology, Vol 12, Iss 1, Pp 1-18 (2024)
Abstract Background Animals of many different species, trophic levels, and life history strategies migrate, and the improvement of animal tracking technology allows ecologists to collect increasing amounts of detailed data on these movements. Underst
Externí odkaz:
https://doaj.org/article/abe92e9399d44ad9b6e9662484080752
Autor:
Bhawna Sharma, Elena Bekerman, Hoa Truong, Johnny Lee, Maria Gamez-Guerrero, Archana Boopathy, Rohit Mital, Katell Bidet Huang, Sarah Ahmadi-Erber, Raphaela Wimmer, Sophie Schulha, Henning Lauterbach, Klaus Orlinger, Silpa Suthram, Mark G. Lewis, Wade Blair, Tariro Makadzange, Romas Geleziunas, Jeffrey P. Murry, Sarah Schmidt
Publikováno v:
Vaccines, Vol 12, Iss 7, p 735 (2024)
Arenavirus-based vectors are being investigated as therapeutic vaccine candidates with the potential to elicit robust CD8 T-cell responses. We compared the immunogenicity of replicating (artPICV and artLCMV) and non-replicating (rPICV and rLCMV) aren
Externí odkaz:
https://doaj.org/article/12cd484f588c476caa2e1468f51b5006
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0307290 (2024)
Restricted, repetitive behaviors are common symptoms in neurodevelopmental disorders including autism spectrum disorder. Despite being associated with poor developmental outcomes, repetitive behaviors remain poorly understood and have limited treatme
Externí odkaz:
https://doaj.org/article/57fb720c9c934a838831442881280495