Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Mark P Hodson"'
Autor:
Marcia A Munoz, Emma K Fletcher, Oliver P Skinner, Julie Jurczyluk, Esther Kristianto, Mark P Hodson, Shuting Sun, Frank H Ebetino, David R Croucher, Philip M Hansbro, Jacqueline R Center, Michael J Rogers
Publikováno v:
eLife, Vol 10 (2021)
Bisphosphonates drugs target the skeleton and are used globally for the treatment of common bone disorders. Nitrogen-containing bisphosphonates act by inhibiting the mevalonate pathway in bone-resorbing osteoclasts but, surprisingly, also appear to r
Externí odkaz:
https://doaj.org/article/efd2366c282f45e0a4b6b5d87db2968d
Autor:
Mareike Bongers, Jordi Perez-Gil, Mark P Hodson, Lars Schrübbers, Tune Wulff, Morten OA Sommer, Lars K Nielsen, Claudia E Vickers
Publikováno v:
eLife, Vol 9 (2020)
Volatile isoprenoids produced by plants are emitted in vast quantities into the atmosphere, with substantial effects on global carbon cycling. Yet, the molecular mechanisms regulating the balance between volatile and non-volatile isoprenoid productio
Externí odkaz:
https://doaj.org/article/3da291e036554f8f9d8e3953b74937f2
Autor:
Utpal Bose, Thanapong Kruangkum, Tianfang Wang, Min Zhao, Tomer Ventura, Shahida Akter Mitu, Mark P Hodson, Paul N Shaw, Prasert Sobhon, Scott F Cummins
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0177064 (2017)
In decapod crustaceans, the antennal gland (AnG) is a major primary source of externally secreted biomolecules, and some may act as pheromones that play a major role in aquatic animal communication. In aquatic crustaceans, sex pheromones regulate rep
Externí odkaz:
https://doaj.org/article/e5764254c7cd444792604691a69379d9
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0147956 (2016)
Carica papaya leaf decoction, an Australian Aboriginal remedy, has been used widely for its healing capabilities against cancer, with numerous anecdotal reports. In this study we investigated its in vitro cytotoxicity on human squamous cell carcinoma
Externí odkaz:
https://doaj.org/article/befb417ee58e482dab455649dc0d663d
Autor:
Utpal Bose, Amitha K Hewavitharana, Miranda E Vidgen, Yi Kai Ng, P Nicholas Shaw, John A Fuerst, Mark P Hodson
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91488 (2014)
Patterns of inter-species secondary metabolite production by bacteria can provide valuable information relating to species ecology and evolution. The complex nature of this chemical diversity has previously been probed via directed analyses of a smal
Externí odkaz:
https://doaj.org/article/40a649f149ca4e2b85e421251d5f658a
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 275, Iss , Pp 116240- (2024)
Modelling approaches to estimate the bioaccumulation of organic chemicals by earthworms are important for improving the realism in risk assessment of chemicals. However, the applicability of existing models is uncertain, partly due to the lack of ind
Externí odkaz:
https://doaj.org/article/fa759e268b304016aeb8777d89008635
Autor:
Stefanie Dietmair, Mark P Hodson, Lake-Ee Quek, Nicholas E Timmins, Peter Gray, Lars K Nielsen
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43394 (2012)
Hek293 cells are the predominant hosts for transient expression of recombinant proteins and are used for stable expression of proteins where post-translational modifications performed by CHO cells are inadequate. Nevertheless, there is little informa
Externí odkaz:
https://doaj.org/article/808fa1a3dcfc44d5a643488fa3d2400b
Autor:
Matthias Keller, David P Enot, Mark P Hodson, Emeka I Igwe, Hans-Peter Deigner, Justin Dean, Hayde Bolouri, Henrik Hagberg, Carina Mallard
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29503 (2011)
Prenatal inflammation is considered an important factor contributing to preterm birth and neonatal mortality and morbidity. The impact of prenatal inflammation on fetal bioenergetic status and the correlation of specific metabolites to inflammatory-i
Externí odkaz:
https://doaj.org/article/d8320831c60a4b47ac46b7ca9022ed2a
Autor:
Marcia A. Munoz, Oliver P. Skinner, Etienne Masle-Farquhar, Julie Jurczyluk, Ya Xiao, Emma K. Fletcher, Esther Kristianto, Mark P. Hodson, Seán I. O’Donoghue, Sandeep Kaur, Robert Brink, David G. Zahra, Elissa K. Deenick, Kristen A. Perry, Avril A.B. Robertson, Sam Mehr, Pravin Hissaria, Catharina M. Mulders-Manders, Anna Simon, Michael J. Rogers
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 19 (2022)
Mevalonate kinase deficiency (MKD) is characterized by recurrent fevers and flares of systemic inflammation, caused by biallelic loss-of-function mutations in MVK. The underlying disease mechanisms and triggers of inflammatory flares are poorly under
Externí odkaz:
https://doaj.org/article/21b5b88799f3482d9c5c720c2d6c2ea8
Publikováno v:
PRX Quantum, Vol 3, Iss 4, p 040339 (2022)
The trading of fidelity for scale enables approximate classical simulators such as matrix product states (MPSs) to run quantum circuits beyond exact methods. A control parameter, the so-called bond dimension χ for MPSs, governs the allocated computa
Externí odkaz:
https://doaj.org/article/68d53106a5714eef8bab348712f031c6