Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Mark P Burns"'
Publikováno v:
PLoS ONE, Vol 18, Iss 7, p e0288363 (2023)
The pathophysiological changes that occur after traumatic brain injury (TBI) can lead to the development of post-traumatic epilepsy, a life-long complication of brain trauma. The etiology of post-traumatic epilepsy remains unknown, but TBI brains exh
Externí odkaz:
https://doaj.org/article/2babeeac2c6c442d8292e7729c372ad7
Autor:
Ji Soo Lee, Yeunkum Lee, Emily A André, Kea Joo Lee, Thien Nguyen, Yang Feng, Nuo Jia, Brent T Harris, Mark P Burns, Daniel T S Pak
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0219691 (2019)
Alzheimer disease (AD) is a neurodegenerative disorder characterized by pathological hallmarks of neurofibrillary tangles and amyloid plaques. The plaques are formed by aggregation and accumulation of amyloid β (Aβ), a cleavage fragment of amyloid
Externí odkaz:
https://doaj.org/article/b0d48a1faca6491aa3a94774c3fdeacf
Autor:
Wendy Noble, Mark P Burns
Publikováno v:
Frontiers in Psychiatry, Vol 1 (2010)
Externí odkaz:
https://doaj.org/article/18f72a9e6f0e42e68f3b6fd3a0a898ef
Autor:
Abdulkader Yassin-Kassab, Nathaniel Wang, Jackson Foley, Tracy Murray Stewart, Mark R. Burns, Robert A. Casero, Jr., R. Alex Harbison, Umamaheswar Duvvuri
Publikováno v:
Oral Oncology Reports, Vol 8, Iss , Pp 100123- (2023)
Background: Surgery and/or platinum-based chemoradiation remain standard of care for patients with head and neck squamous cell carcinoma (HNSCC). While these therapies are effective in a subset of patients, a substantial proportion experience recurre
Externí odkaz:
https://doaj.org/article/fa4cd743a30947f3b9126ba27820f186
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
Glucose is an essential cellular fuel for maintaining normal brain functions. Traumatic brain injury (TBI) decreases brain glucose utilization in both human and experimental animals during the acute or subacute phase of TBI. It remains unclear as to
Externí odkaz:
https://doaj.org/article/1936c6b5dd284e0bbd9c5e60741bf9d5
Autor:
Bevan S. Main, Sonia Villapol, Stephanie S. Sloley, David J. Barton, Maia Parsadanian, Chinyere Agbaegbu, Kathryn Stefos, Mondona S. McCann, Patricia M. Washington, Olga C. Rodriguez, Mark P. Burns
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-18 (2018)
Abstract Background Traumatic Brain Injury (TBI) is a major cause of disability and mortality, to which there is currently no comprehensive treatment. Blood Brain Barrier (BBB) dysfunction is well documented in human TBI patients, yet the molecular m
Externí odkaz:
https://doaj.org/article/05c8f1b3873c40baafca5abfdfecf8ee
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The secondary injury cascade that is activated following traumatic brain injury (TBI) induces responses from multiple physiological systems, including the immune system. These responses are not limited to the area of brain injury; they can also alter
Externí odkaz:
https://doaj.org/article/3de4121a2a41466c815188edbbdb04bd
Publikováno v:
Frontiers in Neuroanatomy, Vol 11 (2018)
Chemokine (C-C motif) ligand 5 (CCL5) belongs to a group of chemokines that play a role in the peripheral immune system, mostly as chemoattractant molecules, and mediate tactile allodynia. In the central nervous system (CNS), CCL5 and its receptors h
Externí odkaz:
https://doaj.org/article/44cc500293bd4f4aa9505b2a14d05b67
Autor:
June Zhou, Mark P. Burns, Linda Huynh, Sonia Villapol, Daniel D. Taub, Juan M. Saavedra, Marc R. Blackman
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
Traumatic brain injury (TBI) causes transient increases and subsequent decreases in brain glucose utilization. The underlying molecular pathways are orchestrated processes and poorly understood. In the current study, we determined temporal changes in
Externí odkaz:
https://doaj.org/article/3c6ebc8e250248cabd9c8cee9d0726e5
Publikováno v:
Biosensors, Vol 4, Iss 1, Pp 76-89 (2014)
We have developed a label-free viscosity-based DNA detection system, using paramagnetic beads as an asynchronous magnetic bead rotation (AMBR) microviscometer. We have demonstrated experimentally that the bead rotation period is linearly proportional
Externí odkaz:
https://doaj.org/article/57b7b943972e4d9aa8fbc98e09761583