Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Mark P, Ward"'
Autor:
Jonathan P Segal, Mayur Garg, Miles P Sparrow, Gareth J Walker, Ashish Srinivasan, Peter De Cruz, Desmond Chee, Alex Boussioutas, Robert V Bryant, Georgina Hold, Gregory T Moore, Susan J Connor, Robert D Little, Mark G Ward, Jo McKenzie, Patrick Hilley, Robert B Gilmore, Manjeet Sandhu, Daniel Saitta, Elizabeth Chow, Lena Thin, Kate Lynch, Jane Andrews, Yoon K An, Emily K Wright
Publikováno v:
BMJ Open, Vol 14, Iss 7 (2024)
Introduction A substantial proportion of patients with inflammatory bowel disease (IBD) on intravenous infliximab require dose intensification. Accessing additional intravenous infliximab is labour-intensive and expensive, depending on insurance and
Externí odkaz:
https://doaj.org/article/c6f1e2d43a834509bfe7e3af4a9f737f
Autor:
Joanna Lazniewska, Ka Lok Li, Ian R. D. Johnson, Alexandra Sorvina, Jessica M. Logan, Carmela Martini, Courtney Moore, Ben S.-Y. Ung, Litsa Karageorgos, Shane M. Hickey, Sarita Prabhakaran, Jessica K. Heatlie, Robert D. Brooks, Chelsea Huzzell, Nicholas I. Warnock, Mark P. Ward, Bashir Mohammed, Prerna Tewari, Cara Martin, Sharon O’Toole, Laura Bogue Edgerton, Mark Bates, Paul Moretti, Stuart M. Pitson, Stavros Selemidis, Lisa M. Butler, John J. O’Leary, Douglas A. Brooks
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract Prostate cancer (PCa) development and progression relies on the programming of glucose and lipid metabolism, and this involves alterations in androgen receptor expression and signalling. Defining the molecular mechanism that underpins this m
Externí odkaz:
https://doaj.org/article/50253ef611194e4595e03d647adf9305
Autor:
Peter R Gibson, Miles P Sparrow, Fan Zhang, Georgina L Hold, Alex Boussioutas, Susan J Connor, Robert D Little, Thisun Jayawardana, Sabrina Koentgen, Mark G Ward
Publikováno v:
eGastroenterology, Vol 2, Iss 1 (2024)
The pathogenesis of inflammatory bowel disease (IBD) is complex and multifactorial. Undertreated disease has substantial individual and societal consequences. Current patient classification and subsequent positioning of IBD therapy are based on crude
Externí odkaz:
https://doaj.org/article/e7dbfb915d5640beb659756b18fe8572
Autor:
Tanya E. Kelly, Cathy L. Spillane, Mark P. Ward, Karsten Hokamp, Yanmei Huang, Prerna Tewari, Cara M. Martin, Lucy A. Norris, Bashir M. Mohamed, Mark Bates, Robert Brooks, Stavros Selemidis, Douglas A. Brooks, Waseem Kamran, Feras Abu Saadeh, Sharon A. O’Toole, John J. O’Leary
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: High-grade serous ovarian cancer (HGSOC) is the most prevalent and deadliest subtype of epithelial ovarian cancer (EOC), killing over 140,000 people annually. Morbidity and mortality are compounded by a lack of screening methods, and re
Externí odkaz:
https://doaj.org/article/33bd691aaea5495980163d42d2344d28
Autor:
Bashir M. Mohamed, Mark P. Ward, Mark Bates, Cathy D. Spillane, Tanya Kelly, Cara Martin, Michael Gallagher, Sheena Heffernan, Lucy Norris, John Kennedy, Feras Abu Saadeh, Noreen Gleeson, Doug A. Brooks, Robert D. Brooks, Stavros Selemidis, Sharon O’Toole, John J. O’Leary
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Circulating tumour cells (CTCs) are a critical intermediate step in the process of cancer metastasis. The reliability of CTC isolation/purification has limited both the potential to report on metastatic progression and the development of CTC
Externí odkaz:
https://doaj.org/article/8a0eceb23e854e889f86fef99c3b1ed3
Publikováno v:
Discrete Mathematics & Theoretical Computer Science, Vol vol. 25:2, Iss Combinatorics (2023)
The analysis of strings of $n$ random variables with geometric distribution has recently attracted renewed interest: Archibald et al. consider the number of distinct adjacent pairs in geometrically distributed words. They obtain the asymptotic ($n\ri
Externí odkaz:
https://doaj.org/article/8a6347e4fe1a4b369bd2ecfed0dcdcb5
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0279813 (2023)
PurposeThis study investigated the prevalence and risk factors of mental and general health symptoms among university students attending in-person and online classes during COVID-19. We also explored their experiences returning to in-person classes a
Externí odkaz:
https://doaj.org/article/1f3f466ea2b3436888a970afc518f58e
Autor:
Mark P. Ward, Laura E. Kane, Lucy A. Norris, Bashir M. Mohamed, Tanya Kelly, Mark Bates, Andres Clarke, Nathan Brady, Cara M. Martin, Robert D. Brooks, Doug A. Brooks, Stavros Selemidis, Sean Hanniffy, Eric P. Dixon, Sharon A. O’Toole, John J. O’Leary
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-17 (2021)
Abstract Cancer cells that transit from primary tumours into the circulatory system are known as circulating tumour cells (CTCs). These cancer cells have unique phenotypic and genotypic characteristics which allow them to survive within the circulati
Externí odkaz:
https://doaj.org/article/6c9b855579b040d7a4a07c53dfa5ef3f
Autor:
Lucy A. Norris, Mark P. Ward, Sharon A. O'Toole, Zibi Marchocki, Nadia Ibrahim, Ali S. Khashan, Feras Abu Saadeh, Noreen Gleeson
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 4, Iss 5, Pp 848-859 (2020)
Abstract Background Gynecologic cancers are associated with high rates of venous thromboembolism (VTE), which is exacerbated by pelvic surgery and chemotherapy. Objectives The aim of this study was to develop and validate a risk score for VTE in pati
Externí odkaz:
https://doaj.org/article/3a9fc531f18040c8b96a7f91eef5372e
Autor:
Cathy D. Spillane, Niamh M. Cooke, Mark P. Ward, Dermot Kenny, Gordon Blackshields, Tanya Kelly, Mark Bates, Yanmei Huang, Cara Martin, Sinead Skehan, Aoife Canney, Michael Gallagher, Paul Smyth, Nathan Brady, Andres Clarke, Bashir Mohamed, Lucy Norris, Doug A. Brooks, Robert D. Brooks, Jessica K. Heatlie, Stavros Selemidis, Sean Hanniffy, Eric Dixon, Orla Sheils, Sharon A. O'Toole, John J. O'Leary
Publikováno v:
Translational Oncology, Vol 14, Iss 12, Pp 101229- (2021)
Tumour metastasis accounts for over 90% of cancer related deaths. The platelet is a key blood component, which facilitates efficient metastasis. This study aimed to understand the molecular mechanisms involved in tumour-platelet cell interactions.The
Externí odkaz:
https://doaj.org/article/96006004b9d1476db6b67d42f80f41fd