Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Mark P, Del Borgo"'
Autor:
Yifang Li, Alex Hunter, Miqdad M. Wakeel, Guizhi Sun, Ricky W. K. Lau, Brad R. S. Broughton, Ivan E. Oyarce Pino, Zihao Deng, Tingfang Zhang, Padma Murthi, Mark P. Del Borgo, Robert E. Widdop, Jose M. Polo, Sharon D. Ricardo, Chrishan S. Samuel
Publikováno v:
Stem Cell Research & Therapy, Vol 15, Iss 1, Pp 1-27 (2024)
Abstract Background Kidney fibrosis is a hallmark of chronic kidney disease (CKD) and compromises the viability of transplanted human bone marrow-derived mesenchymal stromal cells (BM-MSCs). Hence, BM-MSCs were genetically-engineered to express the a
Externí odkaz:
https://doaj.org/article/d6c0ff1090e149c8a2dd546898ac8e05
Autor:
Meg L. McFetridge, Ketav Kulkarni, Volker Hilsenstein, Mark P. Del Borgo, Marie-Isabel Aguilar, Sharon D. Ricardo
Publikováno v:
Nanoscale. 15:1431-1440
Determining the porosity of hydrogels is an important component of material characterisation. While scanning electron microscopy (SEM) is a widely used method to study hydrogel nanoarchitecture, it is well-established that SEM sample preparation meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60fe1d249b3b36d223a39b3d17981704
https://doi.org/10.1039/d2nr04598b
https://doi.org/10.1039/d2nr04598b
Autor:
Nathan Habila, Ketav Kulkarni, Tzong-Hsien Lee, Zahraa S. Al-Garawi, Louise C. Serpell, Marie-Isabel Aguilar, Mark P. Del Borgo
Publikováno v:
Frontiers in Chemistry, Vol 8 (2020)
β3-peptides consisting exclusively of β3-amino acids adopt a variety of non-natural helical structures and can self-assemble into well-defined hierarchical structures by axial head-to-tail self-assembly resulting in fibrous materials of varying siz
Externí odkaz:
https://doaj.org/article/e9019ce2bed94be8a3e24be5011a512d
Autor:
Gabrielle M. Watson, Ketav Kulkarni, Rebecca Brandt, Mark P. Del Borgo, Marie-Isabel Aguilar, Jacqueline A. Wilce
Publikováno v:
ACS Omega, Vol 2, Iss 2, Pp 670-677 (2017)
Externí odkaz:
https://doaj.org/article/4a9b1b5ad0b14cc7b46ffdbeea4c0a11
Autor:
Sepideh Motamed, Mark P. Del Borgo, Kun Zhou, Ketav Kulkarni, Peter J. Crack, Tobias D. Merson, Marie-Isabel Aguilar, David I. Finkelstein, John S. Forsythe
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 7 (2019)
Neural stem cells, which are confined in localised niches are unable to repair large brain lesions because of an inability to migrate long distances and engraft. To overcome these problems, previous research has demonstrated the use of biomaterial im
Externí odkaz:
https://doaj.org/article/ab37ac9151e2435e8ddbe6b4e2b0be95
Publikováno v:
Frontiers in Chemistry, Vol 7 (2019)
Self-assembly is the spontaneous organization of small components into higher-order structures facilitated by the collective balance of non-covalent interactions. Peptide-based self-assembly systems exploit the ability of peptides to adopt distinct s
Externí odkaz:
https://doaj.org/article/54ee31f82d914d3884160941961c8f48
Autor:
Mark P. Del Borgo, Ketav Kulkarni, Mary A. Tonta, Jessie L. Ratcliffe, Rania Seoudi, Adam I. Mechler, Patrick Perlmutter, Helena C. Parkington, Marie-Isabel Aguilar
Publikováno v:
APL Bioengineering, Vol 2, Iss 2, Pp 026104-026104-9 (2018)
Peptides comprised entirely of β3-amino acids, commonly referred to as β-foldamers, have been shown to self-assemble into a range of materials. Previously, β-foldamers have been functionalised via various side chain chemistries to introduce functi
Externí odkaz:
https://doaj.org/article/97c395c00d9e475198bd22e7dd7d965f
Autor:
Rachel L. Minehan, Mark P. Del Borgo
Publikováno v:
Frontiers in Biomaterials Science. 1
Numerous promising drug leads are regularly abandoned due to having poor pharmacokinetic profiles. Biomaterials are often used as drug delivery systems to improve the pharmacokinetics of these otherwise promising drug candidates. Hydrogels are a subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33c885669b399085674169d6da377796
https://doi.org/10.3389/fbiom.2022.916985
https://doi.org/10.3389/fbiom.2022.916985
Autor:
Tim Crook, Eirinaios I. Vrettos, Antonis D. Tsiailanis, Marie-Isabel Aguilar, Thomas Mavromoustakos, Nelofer Syed, Georgios S. Markopoulos, Alexander Renziehausen, Mark P. Del Borgo, Robert E Widdop, Nisar Sayyad, Evangelos Kolettas, Andreas G. Tzakos, Sofia Kiriakidi, Baydaa Hirmiz
Publikováno v:
Free Radical Biology and Medicine. 160:391-402
Glioblastoma multiforme (GBM) is the most common and aggressive primary malignant brain tumor. Maximal surgical resection followed by radiotherapy and concomitant chemotherapy with temozolomide remains the first-line therapy, prolonging the survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c50eff5cb0b367d6a9d222896052e0f
https://doi.org/10.1016/j.freeradbiomed.2020.08.007
https://doi.org/10.1016/j.freeradbiomed.2020.08.007
Autor:
Helena C. Parkington, Tanesh D. Gamot, Susan E. Northfield, Simon Bowles, Robert E Widdop, Rachel L. Minehan, Harold A. Coleman, Richard A. Hughes, Qingqing Lin, Ketav Kulkarni, Marie-Isabel Aguilar, Denham Hopper, Mark P. Del Borgo
Publikováno v:
ACS applied materialsinterfaces. 13(49)
A synthetic strategy for conjugating small molecules and peptide-based therapeutics, via a cleavable ester bond, to a lipidated β3-tripeptide is presented. The drug-loaded β3-peptide was successfully co-assembled with a functionally inert lipidated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::133badf295170796b9ad8b226485980b
https://pubmed.ncbi.nlm.nih.gov/34756031
https://pubmed.ncbi.nlm.nih.gov/34756031