Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mark O. Kitchen"'
Autor:
Pensee Wu, William E. Farrell, Kim E. Haworth, Richard D. Emes, Mark O. Kitchen, John R. Glossop, Fahmy W. Hanna, Anthony A. Fryer
Publikováno v:
Epigenetics, Vol 13, Iss 2, Pp 122-128 (2018)
Several recent reports have described associations between gestational diabetes (GDM) and changes to the epigenomic landscape where the DNA samples were derived from either cord or placental sources. We employed genome-wide 450K array analysis to det
Externí odkaz:
https://doaj.org/article/e67709eef8914d9cb025ab6610835e8a
Publikováno v:
Frontiers in Surgery, Vol 9 (2022)
IntroductionNon-muscle-invasive bladder cancer (NMIBC) is a common and heterogeneous disease; many patients develop recurrent or progress to muscle-invasive disease. Intravesical drug therapy is a pillar in the current management of NMIBC; notwithsta
Externí odkaz:
https://doaj.org/article/d067ec214d1c46ac894c92ebf516ab3b
Publikováno v:
Future Oncology. 18:105-115
Supplies of intravesical Bacillus Calmette-Guérin (BCG), the first-line treatment for most intermediate- and high-risk non-muscle-invasive bladder cancers (NMIBC), have proven unreliable over the past decade. This review considers the evolution of B
Publikováno v:
Journal of Endoluminal Endourology. 4:e1-e7
BackgroundDespite National Institute for Clinical Excellence (NICE) guidelines suggesting the use of urine cytology (UC) for the diagnosis of bladder cancer, its use is variable. Reasons for this include sub-optimal sensitivity, financial cost, avail
Autor:
Sharbathana Nageswaren, Sneha Rathod, Anurag Golash, Jennifer Nowers, Caroline Lipski, Shahjahan Aslam, Mark O. Kitchen
Publikováno v:
Journal of Endoluminal Endourology. 4:e7-e12
Background: Historic evidence suggests up to 16% (approximately) of non-visible haematuria (NVH) referrals result in Urological cancer diagnosis. The majority are bladder cancers, for which flexible cystoscopy is regarded the “gold standard” diag
Autor:
Mark O Kitchen, Richard T Bryan, Kim E Haworth, Richard D Emes, Christopher Luscombe, Lyndon Gommersall, K K Cheng, Maurice P Zeegers, Nicholas D James, Adam J Devall, Anthony A Fryer, William E Farrell
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137003 (2015)
Inappropriate DNA methylation is frequently associated with human tumour development, and in specific cases, is associated with clinical outcomes. Previous reports of DNA methylation in low/intermediate grade non-muscle invasive bladder cancer (NMIBC
Externí odkaz:
https://doaj.org/article/a3cf01557fcd480eb56ec7eac1474195
Aims. Polycystic ovarian syndrome (PCOS) is a common endocrine disorder characterised by ovarian morphological, systemic biochemical, and menstrual changes. Women with PCOS are at significantly increased risk of raised fasting glucose, impaired gluco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49c0cbd257fb324999d1aa19cbd9b0ed
https://doi.org/10.21203/rs.3.rs-637359/v1
https://doi.org/10.21203/rs.3.rs-637359/v1
Autor:
Nir Eynon, Sarah Voisin, Claire E. Stewart, Daniil V. Popov, Piotr P. Gorski, R. Sultanov, I. Dos-Remedios, Philipp Baumert, Daniel J. Owens, Ildus I. Ahmetov, Adam P. Sharples, Ekaterina Semenova, Andrey K. Larin, Edward V. Generozov, Robert A. Seaborne, Robert M. Erskine, Oleg V. Borisov, Alexander D. Brown, Mark O. Kitchen, Mohd Firdaus Maasar, Daniel C. Turner, Barry Drust
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-19 (2020)
Scientific Reports
Scientific Reports
Skeletal muscle tissue demonstrates global hypermethylation with age. However, methylome changes across the time-course of differentiation in aged human muscle derived cells, and larger coverage arrays in aged muscle tissue have not been undertaken.
Autor:
William E. Farrell, Richard D. Emes, Pensee Wu, John R Glossop, Anthony A. Fryer, Fahmy W F Hanna, Kim E. Haworth, Mark O. Kitchen
Publikováno v:
Epigenetics. 13:122-128
Several recent reports have described associations between gestational diabetes (GDM) and changes to the epigenomic landscape where the DNA samples were derived from either cord or placental sources. We employed genome-wide 450Karray analysis to dete
Autor:
Maurice P. Zeegers, Richard T. Bryan, Nicholas D. James, Anthony A. Fryer, John R Glossop, Richard D. Emes, Kar Keung Cheng, Christopher Luscombe, Charles A. Mein, Adam J. Devall, William E. Farrell, Lyndon Gommersall, Mark O. Kitchen
Publikováno v:
Epigenetics, 11(3), 237-246. Landes Bioscience
High-grade non-muscle invasive bladder cancer (HG-NMIBC) is a clinically unpredictable disease with greater risks of recurrence and progression relative to their low-intermediate-grade counterparts. The molecular events, including those affecting the