Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Mark O. Aksoy"'
Autor:
Steven G. Kelsen, Alan S. Braverman, Mark O. Aksoy, Jacob A. Hayman, Puja S. Patel, Charu Rajput, Huaqing Zhao, Susan G. Fisher, Michael R. Ruggieri Sr., Nina T. Gentile
Publikováno v:
JCI Insight, Vol 7, Iss 4 (2022)
BACKGROUND Most individuals with prior COVID-19 disease manifest long-term protective immune responses against reinfection. Accordingly, we tested the hypothesis that humoral immune and reactogenicity responses to a SARS-CoV-2 mRNA vaccine differ in
Externí odkaz:
https://doaj.org/article/07f6174d13a24b0394d2e727f609c373
Autor:
Mark O. Aksoy, Victor Kim, William D. Cornwell, Thomas J. Rogers, Beata Kosmider, Karim Bahmed, Carlos Barrero, Salim Merali, Neena Shetty, Steven G. Kelsen
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-8 (2017)
Abstract Background Identification of biomarkers of cigarette smoke –induced lung damage and early COPD is an area of intense interest. Glucose regulated protein of 78 kD (i.e., GRP78), a multi-functional protein which mediates cell responses to ox
Externí odkaz:
https://doaj.org/article/9661c7fac6544bb69122ed0b711aaa9a
Autor:
Steven G. Kelsen, Alan S. Braverman, Mark O. Aksoy, Jacob A. Hayman, Puja S. Patel, Charu Rajput, Huaqing Zhao, Susan G. Fisher, Michael R. Ruggieri, Nina T. Gentile
Publikováno v:
JCI insight. 7(4)
BACKGROUNDMost individuals with prior COVID-19 disease manifest long-term protective immune responses against reinfection. Accordingly, we tested the hypothesis that humoral immune and reactogenicity responses to a SARS-CoV-2 mRNA vaccine differ in i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3133114e6a5b89b336a5f98f8030fba
https://pubmed.ncbi.nlm.nih.gov/35019861
https://pubmed.ncbi.nlm.nih.gov/35019861
Autor:
Ellen M. Unterwald, Dhanendra Tomar, Elise M. Messier, Muniswamy Madesh, Mark O. Aksoy, Robert J. Mason, Gerard J. Criner, John W. Elrod, Toby K. Eisenstein, Karim Bahmed, Loukmane Karim, Hannah Simborio, Chih-Ru Lin, Steven G. Kelsen, Beata Kosmider
Publikováno v:
Am J Physiol Lung Cell Mol Physiol
The alveolus participates in gas exchange, which can be impaired by environmental factors and toxins. There is an increase in using electronic cigarettes (e-cigarettes); however, their effect on human primary alveolar epithelial cells is unknown. Hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25e94d95d0d9ab48650913f4ae96624
https://doi.org/10.1152/ajplung.00567.2018
https://doi.org/10.1152/ajplung.00567.2018
Autor:
Steven G. Kelsen, Alan S. Braverman, Mark O. Aksoy, Jacob A. Hayman, Puja Patel, Charu Rajput, Huaqing Zhao, Susan G. Fisher, Michael R. Ruggieri, Nina T. Gentile
BackgroundCurrent recommendations in the United States are that subjects with a previous history of COVID-19 disease receive the full 2 dose mRNA vaccine regimen. We tested the hypothesis that humoral immune responses and reactogenicity to a SARS-CoV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e29a66fa47affc0b2fb64d5b7d2e1683
https://doi.org/10.1101/2021.03.18.21253845
https://doi.org/10.1101/2021.03.18.21253845
Autor:
Yolanda Lopez, Mark O. Aksoy, Karthik Mallilankaraman, Salim Merali, Oscar Perez-Leal, Muniswamy Madesh, Steven G. Kelsen, Rong Ji, Gerard J. Criner, Carlos A. Barrero, Camilo Moncada
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 188:673-683
Shifts in the gene expression of nuclear protein in chronic obstructive pulmonary disease (COPD), a progressive disease that is characterized by extensive lung inflammation and apoptosis, are common; however, the extent of the elevation of the core h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50fbdf932430d500369a6f7ff91aca93
https://doi.org/10.1164/rccm.201302-0342oc
https://doi.org/10.1164/rccm.201302-0342oc
Publikováno v:
COPD: Journal of Chronic Obstructive Pulmonary Disease. 5:5-11
The CXC chemokines, IP-10/CXCL10 and IL-8/CXCL8, play a role in obstructive lung disease by attracting Th1/Tc1 lymphocytes and neutrophils, respectively. Inhaled corticosteroids (ICS) and long acting beta 2-agonists (LABA) are widely used. However, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32fe99b211386a9a52c1256ffc521a79
https://doi.org/10.1080/15412550701817573
https://doi.org/10.1080/15412550701817573
Publikováno v:
Journal of Allergy and Clinical Immunology. 109:491-497
Activation of the beta(2)-adrenergic receptor (beta(2)AR) system expressed by human airway epithelial cells elicits a variety of cyclic adenosine monophosphate (cAMP)-dependent processes that help determine airway caliber and the intensity of airway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b2fe93218512431f397d00d2c56f7b
https://doi.org/10.1067/mai.2002.122154
https://doi.org/10.1067/mai.2002.122154
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 281:L1271-L1278
Interleukin (IL)-1β increases β2-adrenergic receptor (β2-AR) mRNA and density by protein kinase C (PKC)-dependent mechanisms in human airway epithelial cells. The present study examined the role of several nuclear transcription factors in the PKC-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e54601e0cbfd7d5b7dda20f7b6d58a
https://doi.org/10.1152/ajplung.2001.281.5.l1271
https://doi.org/10.1152/ajplung.2001.281.5.l1271
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 280:L675-L679
Protein kinase C (PKC)-activated signal transduction pathways regulate cell growth and differentiation in many cell types. We have observed that interleukin (IL)-1β upregulates β2-adrenergic receptor (β2-AR) density and β2-AR mRNA in human airway
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7812546ebd485ef55e321779d1181569
https://doi.org/10.1152/ajplung.2001.280.4.l675
https://doi.org/10.1152/ajplung.2001.280.4.l675