Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Mark O, Cunningham"'
Autor:
Anderson Brito da Silva, Jane Pennifold, Ben Henley, Koustav Chatterjee, David Bateman, Roger W. Whittaker, Abhijit Joshi, Hrishikesh Kumar, Claire Nicholson, Mark R. Baker, Stuart D. Greenhill, Richard Walsh, Stefano Seri, Roland S. G. Jones, Gavin L. Woodhall, Mark O. Cunningham
Publikováno v:
Epilepsia Open, Vol 7, Iss 3, Pp 488-495 (2022)
Abstract Focal cortical dysplasia (FCD) is one of the most common malformations causing refractory epilepsy. Dysregulation of glutamatergic systems plays a critical role in the hyperexcitability of dysplastic neurons in FCD lesions. The pharmacoresis
Externí odkaz:
https://doaj.org/article/4f75c11420504a2b92f84ffdac58cc0c
Autor:
Giovanna O. Nogueira, Patricia P. Garcez, Cedric Bardy, Mark O. Cunningham, Adriano Sebollela
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Externí odkaz:
https://doaj.org/article/fa05b6bffe7f4ce086333a62b5c8f484
Autor:
Michael Spedding, Claude Sebban, Thérèse M. Jay, Cyril Rocher, Brigitte Tesolin-Decros, Paul Chazot, Esther Schenker, Gabor Szénási, György I. Lévay, Katalin Megyeri, Jozsef Barkóczy, Laszlo G. Hársing, Ian Thomson, Mark O. Cunningham, Miles A. Whittington, Lori-An Etherington, Jeremy J. Lambert, Ferenc A. Antoni, Istvan Gacsályi
Publikováno v:
Cells, Vol 11, Iss 7, p 1181 (2022)
Dysfunction in the hippocampus-prefrontal cortex (H-PFC) circuit is a critical determinant of schizophrenia. Screening of pyridazinone-risperidone hybrids on this circuit revealed EGIS 11150 (S 36549). EGIS 11150 induced theta rhythm in hippocampal s
Externí odkaz:
https://doaj.org/article/a9ff5b5911fe463bbd0919d101083673
Autor:
Ingrid Ehrmann, Matthew R. Gazzara, Vittoria Pagliarini, Caroline Dalgliesh, Mahsa Kheirollahi-Chadegani, Yaobo Xu, Eleonora Cesari, Marina Danilenko, Marie Maclennan, Kate Lowdon, Tanja Vogel, Piia Keskivali-Bond, Sara Wells, Heather Cater, Philippe Fort, Mauro Santibanez-Koref, Silvia Middei, Claudio Sette, Gavin J. Clowry, Yoseph Barash, Mark O. Cunningham, David J. Elliott
Publikováno v:
Cell Reports, Vol 17, Iss 12, Pp 3269-3280 (2016)
The brain is made up of trillions of synaptic connections that together form neural networks needed for normal brain function and behavior. SLM2 is a member of a conserved family of RNA binding proteins, including Sam68 and SLM1, that control splicin
Externí odkaz:
https://doaj.org/article/f0ae21a2845440f5b5bb4825a77a395e
Publikováno v:
Reviews in the Neurosciences.
Grid cells, in entorhinal cortex (EC) and related structures, signal animal location relative to hexagonal tilings of 2D space. A number of modeling papers have addressed the question of how grid firing behaviors emerge using (for example) ideas borr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3f8249953270eda798ba1e7476f017
https://doi.org/10.1515/revneuro-2022-0107
https://doi.org/10.1515/revneuro-2022-0107
Autor:
Gareth Morris, Elena Langa, Conor Fearon, Karen Conboy, Kelvin Lau E‐How, Amaya Sanz‐Rodriguez, Donncha F. O'Brien, Kieron Sweeney, Austin Lacey, Norman Delanty, Alan Beausang, Francesca M. Brett, Jane B. Cryan, Mark O. Cunningham, David C. Henshall
Publikováno v:
Epilepsia. 63
IntroductionAn emerging pre-clinical approach for the treatment of pharmacoresistant epilepsy is targeting the microRNA (miRNA) system. MiRNAs are short noncoding RNAs that suppress gene expression at the post-transcriptional level. Targeting miRNAs,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0199c7bc5128c26000a254256b4e3176
https://doi.org/10.1111/epi.17317
https://doi.org/10.1111/epi.17317
Autor:
Giovanna O, Nogueira, Patricia P, Garcez, Cedric, Bardy, Mark O, Cunningham, Adriano, Sebollela
Publikováno v:
Frontiers in neuroscience. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::470c7ba4c3e42e658554b397b843dca1
https://pubmed.ncbi.nlm.nih.gov/35281505
https://pubmed.ncbi.nlm.nih.gov/35281505
Autor:
Claire Nicholson, Hrishikesh Kumar, Gavin L. Woodhall, Richard A. Walsh, Roger W. Whittaker, Stuart D. Greenhill, Abhijit Joshi, Mark O. Cunningham, Anderson Brito da Silva, Jane Pennifold, Ben Henley, Koustav Chatterjee, David Bateman, Mark R. Baker, Stefano Seri, Roland S.G. Jones
Publikováno v:
Epilepsia open. 7(3)
Focal cortical dysplasia (FCD) is one of the most common malformations causing refractory epilepsy. Dysregulation of glutamatergic systems plays a critical role in the hyperexcitability of dysplastic neurons in FCD lesions. The pharmacoresistant natu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc8481ea5175d14149b08bb80cf38cd1
https://pubmed.ncbi.nlm.nih.gov/34653311
https://pubmed.ncbi.nlm.nih.gov/34653311
Autor:
Elizabeth Tilley, Caroline M. Voss, Douglass M. Turnbull, Nichola Z. Lax, Zoe Powell, Mark O. Cunningham, Blanca I. Aldana, Sophie Nichols, Ceri H. Davies, Alistair Jenkins, Shuna Whyte, Felix Chan, Claire Nicholson, Helle S. Waagepetersen
Publikováno v:
Brain. 142:391-411
Approximately one-quarter of patients with mitochondrial disease experience epilepsy. Their epilepsy is often severe and resistant towards conventional antiepileptic drugs. Despite the severity of this epilepsy, there are currently no animal models a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c142aaee585b28d68c12ad95346f158f
https://doi.org/10.1093/brain/awy320
https://doi.org/10.1093/brain/awy320
Autor:
Hugh J Delaney, Louise Riggs-Miller, Anouchka Lewis, Delphine Boche, Steven G. Fagan, Ana Belen Lopez-Rodriguez, Mark O. Cunningham, Carol L. Murray, Daire Healy, Arshed Nazmi, Colm Cunningham, Philip Scarry, Niamh de Barra, Michael Rooney, Edel Hennessy, Erika Stewart
Publikováno v:
Alzheimers Dement
Neuroinflammation contributes to Alzheimer's disease (AD) progression. Secondary inflammatory insults trigger delirium and can accelerate cognitive decline. Individual cellular contributors to this vulnerability require elucidation. Using APP/PS1 mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7134059854adc513b3f18cf478d187be
https://pubmed.ncbi.nlm.nih.gov/34080771
https://pubmed.ncbi.nlm.nih.gov/34080771