Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mark N Read"'
Autor:
Jorge Luis Galeano Niño, Sophie V Pageon, Szun S Tay, Feyza Colakoglu, Daryan Kempe, Jack Hywood, Jessica K Mazalo, James Cremasco, Matt A Govendir, Laura F Dagley, Kenneth Hsu, Simone Rizzetto, Jerzy Zieba, Gregory Rice, Victoria Prior, Geraldine M O'Neill, Richard J Williams, David R Nisbet, Belinda Kramer, Andrew I Webb, Fabio Luciani, Mark N Read, Maté Biro
Publikováno v:
eLife, Vol 9 (2020)
Cytotoxic T lymphocytes (CTLs) are thought to arrive at target sites either via random search or following signals by other leukocytes. Here, we reveal independent emergent behaviour in CTL populations attacking tumour masses. Primary murine CTLs coo
Externí odkaz:
https://doaj.org/article/d671480f3ae34c5f99f6cf4e7a7c2792
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 9, p e1005082 (2016)
The advent of two-photon microscopy now reveals unprecedented, detailed spatio-temporal data on cellular motility and interactions in vivo. Understanding cellular motility patterns is key to gaining insight into the development and possible manipulat
Externí odkaz:
https://doaj.org/article/08dd48a532c843b28d2f9c2d1989b8ab
Autor:
Juan P. Molina Ortiz, Dale D. McClure, Erin R. Shanahan, Fariba Dehghani, Andrew J. Holmes, Mark N. Read
Publikováno v:
Gut Microbes, Vol 13, Iss 1 (2021)
The gut microbiome has emerged as a contributing factor in non-communicable disease, rendering it a target of health-promoting interventions. Yet current understanding of the host-microbiome dynamic is insufficient to predict the variation in interve
Externí odkaz:
https://doaj.org/article/8546deaef2c0469bb5f3f78da27fef11
Autor:
Imogen Moran, Akira Nguyen, Weng Hua Khoo, Danyal Butt, Katherine Bourne, Clara Young, Jana R. Hermes, Maté Biro, Gary Gracie, Cindy S. Ma, C. Mee Ling Munier, Fabio Luciani, John Zaunders, Andrew Parker, Anthony D. Kelleher, Stuart G. Tangye, Peter I. Croucher, Robert Brink, Mark N. Read, Tri Giang Phan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Memory B cells need to be reactivated to produce high affinity antibody responses on subsequent antigen encounters. Here the authors show that memory B cells localise to lymph node subcapsular proliferative foci (SPF), which have distinct properties
Externí odkaz:
https://doaj.org/article/434c7143b0dc490799e9dd7d746d107f
Autor:
Givanna H. Putri, Jonathan Chung, Davis N. Edwards, Felix Marsh‐Wakefield, Irena Koprinska, Suat Dervish, Nicholas J. C. King, Thomas M. Ashhurst, Mark N. Read
Publikováno v:
Cytometry Part A. 103:54-70
Mapping the dynamics of immune cell populations over time or disease-course is key to understanding immunopathogenesis and devising putative interventions. We present TrackSOM, a novel method for delineating cellular populations and tracking their de
Autor:
Mark N. Read, Andrew J. Holmes
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Over the last 20 years, a sizeable body of research has linked the microbiome and host diet to a remarkable diversity of diseases. Yet, unifying principles of microbiome assembly or function, at levels required to rationally manipulate a specific ind
Externí odkaz:
https://doaj.org/article/d60ed7ff77db43c8a0ba3279e32ec6e7
Autor:
Felix Marsh‐Wakefield, Pierre Juillard, Thomas M Ashhurst, Annette Juillard, Diana Shinko, Givanna H Putri, Mark N Read, Helen M McGuire, Scott N Byrne, Simon Hawke, Georges E Grau
Publikováno v:
Immunology and cell biology. 100(6)
B cells play a major role in multiple sclerosis (MS), with many successful therapeutics capable of removing them from circulation. One such therapy, alemtuzumab, is thought to reset the immune system without the need for ongoing therapy in a proporti
Autor:
Givanna H. Putri, Jonathan Chung, Davis N. Edwards, Felix Marsh-Wakefield, Suat Dervish, Irena Koprinska, Nicholas J.C. King, Thomas M. Ashhurst, Mark N. Read
Mapping the dynamics of immune cell populations over time or disease-course is key to understanding immunopathogenesis and devising putative interventions. We present TrackSOM, an algorithm which delineates cellular populations and tracks their devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b54f3b1c805468f2e7d7b97af050e34b
https://doi.org/10.1101/2021.06.08.447468
https://doi.org/10.1101/2021.06.08.447468
Autor:
Noa, Lamm, Mark N, Read, Max, Nobis, David, Van Ly, Scott G, Page, V Pragathi, Masamsetti, Paul, Timpson, Maté, Biro, Anthony J, Cesare
Publikováno v:
Nature cell biology. 22(12)
Filamentous actin (F-actin) provides cells with mechanical support and promotes the mobility of intracellular structures. Although F-actin is traditionally considered to be cytoplasmic, here we reveal that nuclear F-actin participates in the replicat