Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mark Mizrahi"'
Autor:
David Margel, Mark Mizrahi, Gili Regev-Shoshani, Mary Ko, Maya Moshe, Rachel Ozalvo, Liat Shavit-Grievink, Jack Baniel, Daniel Kedar, Ofer Yossepowitch, David Lifshitz, Andrei Nadu, David Greenberg, Yossef Av-Gay
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174443 (2017)
Catheter-Associated Hospital-Acquired Infections (HAI's) are caused by biofilm-forming bacteria. Using a novel approach, we generated anti-infective barrier on catheters by charging them with Nitric Oxide (NO), a naturally-produced gas molecule. NO i
Externí odkaz:
https://doaj.org/article/7c96d609d220443bb7a5ecf96bc77ad3
Autor:
Boris M. Baranovski, Omer Nisim, Ronen Schuster, Nofar Bahar, Eli C. Lewis, Galit Shahaf, Noa Kalay, Pablo Cal, Eran Schenker, Eyal Ozeri, David E. Ochayon, Mark Mizrahi, Pnina Strauss
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics
Lifelong weekly infusions of human α1-antitrypsin (hAAT) are currently administered as augmentation therapy for patients with genetic AAT deficiency (AATD). Several recent clinical trials attempt to extend hAAT therapy to conditions outside AATD, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b04d8a1471437b9fe905b744d4cf9592
https://doi.org/10.1124/jpet.116.236067
https://doi.org/10.1124/jpet.116.236067
Autor:
Lior Carmon, Aviv Goldbart, Ronit Lubetzky, Ronen Spiegel, Inbal Golan-Tripto, Galit Levnat-Levanon, Moran Lavie, Amit Nachum, Giora Pillar, Ori Efrati, Mark Mizrahi
Publikováno v:
Paediatric respiratory infection and immun..
Acute viral bronchiolitis is the most common lower respiratory infection in early infancy and a leading cause of infant hospitalization. The treatment of bronchiolitis is largely supportive. Inhaled nitric oxide (NO) has pulmonary vasodilatory proper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6ad004c16f428e3986d90678b2551ab
https://doi.org/10.1183/13993003.congress-2018.pa4642
https://doi.org/10.1183/13993003.congress-2018.pa4642
Publikováno v:
Open Forum Infectious Diseases. 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f755bc32a1dffa6e0a2768957011181
https://doi.org/10.1093/ofid/ofw172.256
https://doi.org/10.1093/ofid/ofw172.256
Publikováno v:
Molecular Medicine. 17:1000-1011
Antiinflammatory clinical-grade, plasma-derived human α-1 antitrypsin (hAAT) protects islets from allorejection as well as from autoimmune destruction. hAAT also interferes with disease progression in experimental autoimmune encephalomyelitis (EAE)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc2a60e4666059348a87eff4e259a706
https://doi.org/10.2119/molmed.2011.00145
https://doi.org/10.2119/molmed.2011.00145
Autor:
Joanne L. Wright, Nathaniel DeFelice, Charles A. Dinarello, Leland Shapiro, Mark Mizrahi, Eli C. Lewis, Michel B. Toledano, Andrew Churg
Publikováno v:
Proceedings of the National Academy of Sciences. 105:16236-16241
Human pancreatic islet transplantation offers diabetic patients tight glucose control but has low graft survival rates. The immunosuppressive drugs that are administered to graft recipients lack the antiinflammatory benefits of corticosteroids becaus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbed34988c1e270accd0401c6f8fd34b
https://doi.org/10.1073/pnas.0807627105
https://doi.org/10.1073/pnas.0807627105
Autor:
Boris M. Baranovski, Nofar Bahar, Ido Brami, Ronen Schuster, Noa Kalay, David E. Ochayon, Mark Mizrahi, Gabriella S. Freixo-Lima, Ofer Guttman, Ziv Kaner, Eli C. Lewis
Summary One would assume that the anti-inflammatory activity of α1-anti-trypsin (AAT) is the result of inhibiting neutrophil enzymes. However, AAT exhibits tolerogenic activities that are difficult to explain by serine-protease inhibition or by redu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c704d4f3287b82b376773f5cce44aea3
https://europepmc.org/articles/PMC4298394/
https://europepmc.org/articles/PMC4298394/
Autor:
Mark Mizrahi, Jack Baniel, David Greenberg, Mary Ko, Daniel Kedar, Rachel Ozalvo, Gili Regev-Shoshani, Maya Moshe, Liat Shavit-Grievink, Ofer Yossepowitch, Andrei Nadu, David A. Lifshitz, Yossef Av-Gay, David Margel
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0174443 (2017)
PLoS ONE
PLoS ONE
Background Catheter-Associated Hospital-Acquired Infections (HAI's) are caused by biofilm-forming bacteria. Using a novel approach, we generated anti-infective barrier on catheters by charging them with Nitric Oxide (NO), a naturally-produced gas mol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1542b8882f0db567db61216e82564dd3
https://doi.org/10.1371/journal.pone.0174443
https://doi.org/10.1371/journal.pone.0174443
Autor:
Boris M. Baranovski, Eli C. Lewis, Mark Mizrahi, Nofar Bahar, David E. Ochayon, Galit Shahaf, Ziv Kaner
Publikováno v:
The Journal of infectious diseases. 211(9)
Background Severe bacterial infection can cause sepsis, multiple organ dysfunction syndrome (MODS), and death. Human α1-antitrypsin (hAAT) is an antiinflammatory, immune-modulating, and tissue-protective circulating serine-protease inhibitor, with l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::412e1212677c1899ec262fbd2e54c63c
https://pubmed.ncbi.nlm.nih.gov/25389308
https://pubmed.ncbi.nlm.nih.gov/25389308
Publikováno v:
Frontiers in Immunology, Vol 4 (2013)
Frontiers in Immunology
Frontiers in Immunology
The extracellular form of the abundant heat-shock protein, gp96, is involved in human autoimmune pathologies. In patients with type 1 diabetes, circulating gp96 is found to be elevated, and is bound to the acute-phase protein, α1-antitrypsin (AAT).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4221ec8a0ef10d62cd297f13bd53327c
http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00320/full
http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00320/full