Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Mark Meloche"'
Publikováno v:
International Journal of Endocrinology, Vol 2012 (2012)
Islet cell transplantation offers a potential cure for type 1 diabetes, but it is challenged by insufficient donor tissue and side effects of current immunosuppressive drugs. Therefore, alternative sources of insulin-producing cells and isletfriendly
Externí odkaz:
https://doaj.org/article/00b667b493bb4db7b7d57316e53182d0
Autor:
Xiaojie Wang, Jianqiang Hao, Daniel L. Metzger, Ziliang Ao, Mark Meloche, C. Bruce Verchere, Lieping Chen, Dawei Ou, Alice Mui, Garth L. Warnock
Publikováno v:
Journal of Transplantation, Vol 2011 (2011)
Type 1 diabetes (T1D) is a chronic autoimmune disease and characterized by absolute insulin deficiency. β-cell replacement by islet cell transplantation has been established as a feasible treatment option for T1D. The two main obstacles after islet
Externí odkaz:
https://doaj.org/article/a65e6589fd094c0ab878c5d910be7c30
Publikováno v:
Journal of Transplantation, Vol 2011 (2011)
Islet cell transplantation is currently the only feasible long-term treatment option for patients with type 1 diabetes. However, the majority of transplanted islets experience damage and apoptosis during the isolation process, a blood-mediated inflam
Externí odkaz:
https://doaj.org/article/0c564eb16631439eb2a89757c97e1658
Autor:
Ali Asadi, Yoo Jin Park, Mark Meloche, Lucy Marzban, Garth L. Warnock, Timothy J. Kieffer, Ziliang Ao, Nooshin Safikhan
Publikováno v:
Diabetes, Obesity and Metabolism. 19:682-694
Aims Islet amyloid, formed by aggregation of human islet amyloid polypeptide (hIAPP), contributes to β-cell failure in type 2 diabetes, cultured and transplanted islets. We previously showed that biosynthetic hIAPP aggregates induce β-cell Fas upre
Autor:
Garth L. Warnock, Adam Meneghetti, Chris Zroback, Mark Meloche, Chieh Jack Chiu, Geoffrey Chow, Ormond N.M. Panton
Publikováno v:
The American Journal of Surgery. 211:933-937
Background Bile duct injury remains a worrisome complication of laparoscopic cholecystectomy. Indocyanine Green (ICG) fluorescent cholangiography (FC) is a new approach that facilitates real-time intraoperative identification of biliary anatomy. This
Autor:
Stephen G.F. Ho, David M. Liu, Avnesh S. Thakor, Mark Meloche, Bippan S. Sangha, Garth L. Warnock
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 100:1230-1233
Context: Traumatic pancreatic injury with pancreatic duct disruption is surgically managed with at least a partial pancreatectomy, often leading to poor blood glucose control and the subsequent development of diabetes mellitus. Autologous β-islet ce
Autor:
Michelle Fung, David M. Thompson, Ziliang Ao, Breay W. Paty, Claire Harris, Suet On Tong, Graydon S. Meneilly, Sharon E. Kozak, Mohammed Al Mehthel, Blake Fensom, Mark Meloche, Garth L. Warnock, Stephen K. N. Ho, Joma Kondi, Paul Keown, Iain S. Begg, Mary Trinh, Dan Worsley, R. Jean Shapiro
Publikováno v:
Transplantation. 91:373-378
Background The effect of islet cell transplantation (ICT) on the progression of diabetic microvascular complications is not well understood. Methods We have conducted a prospective, crossover, cohort study comparing ICT with intensive medical therapy
Autor:
Khalid Al Ghofaili, R. Jean Shapiro, Mary Trinh, Dan Worsley, Blake Fensom, Garth L. Warnock, Ziliang Ao, Robert M. Kozak, Lorraine Blackburn, Mark Meloche, Suet On Tong, Graydon S. Meneilly, Sharon E. Kozak, Michelle Fung, David M. Thompson, Stephen K. N. Ho, Paul Keown
Publikováno v:
Transplantation. 84:17-22
Background. The effect of islet cell transplantation (ICT) on renal function in type 1 diabetes is uncertain and some recent studies report a significant decline in estimated glomerular filtration rate (GFR) and worsening of albuminuria. Methods. We
Autor:
James D. Johnson, David Thompson, R. Jean Shapiro, Paul Keown, Michelle Fung, Mark Meloche, Ziliang Ao, Breay W. Paty, Graydon S. Meneilly, Garth Warnock, Stephen G.F. Ho, Bruce Vechere
Publikováno v:
Therapeutic Delivery Solutions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::707a7d018b40d3149948e6f9fb704ec9
https://doi.org/10.1002/9781118903681.ch7
https://doi.org/10.1002/9781118903681.ch7
Autor:
Richard K. Simons, Garth L. Warnock, David Ross Brown, Sean Dean, Charles H. Scudamore, Naisan Garraway, Mark Meloche, Andrzej K. Buczkowski
Publikováno v:
Journal of Trauma: Injury, Infection & Critical Care. 67:E187-E189