Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mark Meisenbach"'
Publikováno v:
Organicbiomolecular chemistry. 19(11)
We herein report two complementary strategies employing organolithium chemistry for the synthesis of glyoxal derivatives. Micro-mixer technology allows for the generation of unstable organometallic intermediates and their instantaneous in-line quench
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f82a39944011f5ef73618adc6b2d3636
https://pubmed.ncbi.nlm.nih.gov/33646230
https://pubmed.ncbi.nlm.nih.gov/33646230
Autor:
Susanne Glowienke, Mark Meisenbach, Jerome Andre, Berthold Schenkel, Fabio Lima, Benjamin Martin, Alexander Marziale, Andreas Greb, Joerg Sedelmeier
Publikováno v:
Organic letters. 22(15)
An enabling continuous flow setup for handling of unstable organolithium intermediates and synthesis of heteroaryl sulfinates on a multigram scale is described. The developed continuous flow process allows for the synthesis and simple isolation of he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1a7fb08980529d112326e54f273a84
https://pubmed.ncbi.nlm.nih.gov/32705872
https://pubmed.ncbi.nlm.nih.gov/32705872
Publikováno v:
Organic Letters. 19:786-789
A simple and robust procedure for the synthesis and use of thermally unstable dichloromethyllithium in continuous flow mode is described. By utilizing residence times in the range of milliseconds for the generation and electrophilic quench of dichlor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b0074b518574229a49193cd9bf1c7b
https://doi.org/10.1021/acs.orglett.6b03753
https://doi.org/10.1021/acs.orglett.6b03753
Autor:
Mark Meisenbach, Lorenzo Piccioni, Joerg Sedelmeier, Berthold Schenkel, Andreas Hafner, Paolo Filipponi, Francesco Venturoni
Publikováno v:
Organic Process Research & Development. 20:1833-1837
A platform for conducting organolithium chemistry in continuous flow mode, covering the scales from medicinal chemistry to later phase process development, is described. The use of this flow setup, which mimics the concept of flash chemistry on scale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ca0d38155ae88cae734b6be78ea2d7d
https://doi.org/10.1021/acs.oprd.6b00281
https://doi.org/10.1021/acs.oprd.6b00281
Publikováno v:
Organic Letters. 18:3630-3633
The benefits and limitations of a simple continuous flow setup for handling and performing of organolithium chemistry on the multigram scale is described. The developed metalation platform embodies a valuable complement to existing methodologies, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::733f097b176a7a2364d6200daacbef8d
https://doi.org/10.1021/acs.orglett.6b01681
https://doi.org/10.1021/acs.orglett.6b01681
Publikováno v:
ChemInform. 47
The benefits and limitations of a simple continuous flow setup for handling and performing of organolithium chemistry on the multigram scale is described. The developed metalation platform embodies a valuable complement to existing methodologies, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::219803d32fcddacb73825295f6da521a
https://doi.org/10.1002/chin.201651188
https://doi.org/10.1002/chin.201651188
Publikováno v:
Organic Process Research & Development. 7:553-558
The solid-phase synthesis of 4-(2-amino-6-phenylpyrimidin-4-yl)benzamide, a compound obtained through combinatorial chemistry and parallel synthesis, can be scaled up directly on solid support in excellent yields and high purity. By applying highly l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3371345b8bf3ad4559d85bb66819b756
https://doi.org/10.1021/op034032t
https://doi.org/10.1021/op034032t
Autor:
René Thürmer, W. Schmitt-Sody, Raed A. Al-Qawasmeh, U. Korff, Hartmut Echner, Mark Meisenbach, Angelika Weiler, Wolfgang Voelter
Publikováno v:
Rapid Communications in Mass Spectrometry. 12:398-402
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f7c7ae79d6f79a34e5bf09d54634334
https://doi.org/10.1002/(sici)1097-0231(19980415)12:7<398::aid-rcm171>3.0.co
https://doi.org/10.1002/(sici)1097-0231(19980415)12:7<398::aid-rcm171>3.0.co
Publikováno v:
Liebigs Annalen. 1997:1871-1876
A new strategy for the construction of the O-glycoside bond in the nephritogenoside unit using the phenylsulfenyl method is reported. The readily accessible phenylsulfinyl glycoside proved to be an excellent glycosyl donor, leading to high yields and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8588c97de9282ca6d122e5d7dad68783
https://doi.org/10.1002/jlac.199719970910
https://doi.org/10.1002/jlac.199719970910
Publikováno v:
Liebigs Annalen. 1995:689-695
A New Synthetic Strategy for the Synthesis of Chiral Polysubstituted Tetrahydrofurans Annulated to Pyranoses An efficient strategy for the regio- and stereoselective synthesis of the chiral tetrahydrofurans 2, 3, 5, 6, 10–16, fused to the pyranose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dbca52ee449b5b091df5cdb481853cd
https://doi.org/10.1002/jlac.199519950498
https://doi.org/10.1002/jlac.199519950498