Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Mark McCole"'
Autor:
Geoff S. Higgins, Ruth E. Macpherson, Francesca M. Buffa, Daniel Bulte, Adrian L. Harris, W. Gillies McKenna, Fergus V. Gleeson, James P.B. O’Connor, Jane Holmes, Cathy Qi, Helen Flight, Paula L. Croal, Petra Ferencz, Leticia Campo, Lisa K. Folkes, Remko Prevo, Gonzalo Rodriguez-Berriguete, Marcus Green, Joshua A. Bull, Philip S. Macklin, Benjamin H.L. Harris, Dawn O’Reilly, Jagat Chauhan, Eugene Teoh, Kwun-Ye Chu, Jennifer L. Derham, Mark McCole, Dionisios Stavroulias, Francesco Di Chiara, Elizabeth Belcher, Daniel R. McGowan, Michael Skwarski
Supplementary Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dfeeee5036e9bf1bbf90f8c52150f61
https://doi.org/10.1158/1078-0432.22482990
https://doi.org/10.1158/1078-0432.22482990
Autor:
Geoff S. Higgins, Ruth E. Macpherson, Francesca M. Buffa, Daniel Bulte, Adrian L. Harris, W. Gillies McKenna, Fergus V. Gleeson, James P.B. O’Connor, Jane Holmes, Cathy Qi, Helen Flight, Paula L. Croal, Petra Ferencz, Leticia Campo, Lisa K. Folkes, Remko Prevo, Gonzalo Rodriguez-Berriguete, Marcus Green, Joshua A. Bull, Philip S. Macklin, Benjamin H.L. Harris, Dawn O’Reilly, Jagat Chauhan, Eugene Teoh, Kwun-Ye Chu, Jennifer L. Derham, Mark McCole, Dionisios Stavroulias, Francesco Di Chiara, Elizabeth Belcher, Daniel R. McGowan, Michael Skwarski
Purpose:Tumor hypoxia fuels an aggressive tumor phenotype and confers resistance to anticancer treatments. We conducted a clinical trial to determine whether the antimalarial drug atovaquone, a known mitochondrial inhibitor, reduces hypoxia in non–
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee0906251ef98712c4b6555ffa3022c
https://doi.org/10.1158/1078-0432.c.6531051
https://doi.org/10.1158/1078-0432.c.6531051
Autor:
Geoff S. Higgins, Ruth E. Macpherson, Francesca M. Buffa, Daniel Bulte, Adrian L. Harris, W. Gillies McKenna, Fergus V. Gleeson, James P.B. O’Connor, Jane Holmes, Cathy Qi, Helen Flight, Paula L. Croal, Petra Ferencz, Leticia Campo, Lisa K. Folkes, Remko Prevo, Gonzalo Rodriguez-Berriguete, Marcus Green, Joshua A. Bull, Philip S. Macklin, Benjamin H.L. Harris, Dawn O’Reilly, Jagat Chauhan, Eugene Teoh, Kwun-Ye Chu, Jennifer L. Derham, Mark McCole, Dionisios Stavroulias, Francesco Di Chiara, Elizabeth Belcher, Daniel R. McGowan, Michael Skwarski
Supplementary Figures and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e4f1eca65390f075ca2307e369d9ff0
https://doi.org/10.1158/1078-0432.22482996.v1
https://doi.org/10.1158/1078-0432.22482996.v1
Publikováno v:
Cancer Prevention Through Early Detection ISBN: 9783031179785
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::137923c34560bd1d56185d25b20804c2
https://doi.org/10.1007/978-3-031-17979-2_12
https://doi.org/10.1007/978-3-031-17979-2_12
Autor:
Stephen Damato, Mark McCole, S Smyth, M Alazzam, H Jiang, H Soleymani Majd, Catherine Johnson, S Wood, C Pappa
Publikováno v:
E-Posters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::828f7b554e02ded96ae61ec43d7f8fe2
https://doi.org/10.1136/ijgc-2021-igcs.150
https://doi.org/10.1136/ijgc-2021-igcs.150
Autor:
Mark McCole, Eihab O Bedawi, Najib M. Rahman, Fergus V. Gleeson, Gareth D Turner, Thomas Moore
Publikováno v:
Thorax
A 45-year-old Caucasian woman was referred for investigation of recurrent chest infections. She had been treated over the previous 9 months for recurrent symptoms characterised by intermittent episodes of dyspnoea, cough productive of green sputum an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56390809f9b8049c370799bbd2906722
https://doi.org/10.1136/thoraxjnl-2020-216168
https://doi.org/10.1136/thoraxjnl-2020-216168
Autor:
Andy Beale, Gabriel Sc Yiin, Mark McCole, Henrietta Helliwell, Gopinath Ramadurai, Badrinathan Chandrasekaran, Aishwarya Desai
Publikováno v:
Clinical Medicine. 20:597-599
We describe a rare case of a 69-year-old woman presenting with sudden onset right-sided weakness, sensory disturbance and dysarthria due to a left-middle cerebral artery territory stroke. The patient was successfully thrombolysed, but shortly develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49cbde59e6b5e1499044aeefd2d70f5e
https://doi.org/10.7861/clinmed.2020-0763
https://doi.org/10.7861/clinmed.2020-0763
Autor:
C Qi, Dionisios Stavroulias, J L Derham, Michael Skwarski, E Belcher, Joshua A. Bull, P Ferencz, Chu K-Y., Fergus V. Gleeson, Daniel P. Bulte, Paula L. Croal, Francesca M. Buffa, Adrian L. Harris, O’Connor Jpb., Marcus Green, Harris Bhl., H Flight, Leticia Campo, D O’Reilly, J Chauhan, Jane Holmes, Mark McCole, Geoff S. Higgins, Gonzalo Rodriguez-Berriguete, F Di Chiara, W G McKenna, Eugene Teoh, Lisa K. Folkes, Ruth MacPherson, Daniel R. McGowan, Philip S. Macklin, Remko Prevo
Publikováno v:
Clin Cancer Res
Purpose: Tumor hypoxia fuels an aggressive tumor phenotype and confers resistance to anticancer treatments. We conducted a clinical trial to determine whether the antimalarial drug atovaquone, a known mitochondrial inhibitor, reduces hypoxia in non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aacc9a0024cedfd7332836a2f33e4c90
https://pubmed.ncbi.nlm.nih.gov/33597271
https://pubmed.ncbi.nlm.nih.gov/33597271
Autor:
Yanchun Peng, Daniel Ebner, Tao Dong, Nikolaos I. Kanellakis, Vineeth George, Robert J. Hallifax, Mark McCole, Eihab O Bedawi, Stephanie B Hatch, Xuan Yao, Rachelle Asciak, Rachel M. Mercer, Melissa Dobson, Ioannis Psallidas, Clare Verrill, Megat Abd Hamid, Simon J. McGowan, Najib M. Rahman, Stephanie Jones, Georgios T. Stathopoulos, Elena Seraia
Publikováno v:
Thorax 75, 1004-1008 (2020)
Thorax
Thorax
Malignant pleural mesothelioma (MPM) is an aggressive cancer, associated with poor prognosis. We assessed the feasibility of patient-derived cell cultures to serve as an ex vivo model of MPM. Patient-derived MPM cell cultures (n=16) exhibited stemnes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c15d69705fab5d9a679f3b478e6b9124
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=60380
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=60380
Autor:
Yanchun Peng, Simon J. McGowan, Rachel M. Mercer, Fabien Maldonado, Timothy S. Blackwell, Georgios T. Stathopoulos, Xuan Yao, Najib M. Rahman, Nikolaos I. Kanellakis, L Psallidas, Daniel Ebner, Mark McCole, Rachelle Asciak, Tao Dong, Robert J. Hallifax, Taylor P. Sherrill
Publikováno v:
Pleural and mediastinal malignancies.
Background: Malignant pleural mesothelioma (MPM) is an incurable and aggressive malignancy, which is typically presented with malignant pleural effusion (MPE), bearing severely comprised quality of life and short survival. Since management of MPE rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a32eefaaf15bc7fa8121889d34f8ab6a
https://doi.org/10.1183/13993003.congress-2019.oa3798
https://doi.org/10.1183/13993003.congress-2019.oa3798