Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mark Mattingly"'
Autor:
Alexandria J Cockrell, Jeffrey J Lange, Christopher Wood, Mark Mattingly, Scott M McCroskey, William D Bradford, Juliana Conkright-Fincham, Lauren Weems, Monica S Guo, Jennifer L Gerton
Publikováno v:
PLoS Genetics, Vol 20, Iss 7, p e1011331 (2024)
Nucleolar morphology is a well-established indicator of ribosome biogenesis activity that has served as the foundation of many screens investigating ribosome production. Missing from this field of study is a broad-scale investigation of the regulatio
Externí odkaz:
https://doaj.org/article/1b5df90b2dd94b169054ebf987bcf056
Metabolite-Specific Echo Planar Imaging for Preclinical Studies with Hyperpolarized 13C-Pyruvate MRI
Autor:
Sule I. Sahin, Xiao Ji, Shubhangi Agarwal, Avantika Sinha, Ivina Mali, Jeremy W. Gordon, Mark Mattingly, Sukumar Subramaniam, John Kurhanewicz, Peder E. Z. Larson, Renuka Sriram
Publikováno v:
Tomography, Vol 9, Iss 2, Pp 736-749 (2023)
Metabolite-specific echo-planar imaging (EPI) sequences with spectral–spatial (spsp) excitation are commonly used in clinical hyperpolarized [1-13C]pyruvate studies because of their speed, efficiency, and flexibility. In contrast, preclinical syste
Externí odkaz:
https://doaj.org/article/763209506d174be688ddd0fa55f4861f
Autor:
Chris Oliver, Laura Groves, Blake D. Hansen, Masoud Salehi, Shaydah Kheradmand, Cheri S. Carrico, Patti Caudill, Mark Mattingly, Dale Dorsett, Stephenson Chea, Vijay Pratap Singh, Ian D. Krantz, Sylvia Huisman, Matthew A. Deardorff, Antonie D. Kline
Publikováno v:
American Journal of Medical Genetics Part A. 188:1005-1014
Cornelia de Lange syndrome (CdLS) is a spectrum disorder due to variants in genes of the cohesin protein complex. The following abstracts are from the Cornelia de Lange Syndrome Scientific and Educational Symposium held virtually in October 2020. Asp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fba88a08a5cca0354f8fa3e280291fb
https://doi.org/10.1002/ajmg.a.62591
https://doi.org/10.1002/ajmg.a.62591
Publikováno v:
Digitale Welt. 5:104-109
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03319bf76c128c548061bc4606286609
https://doi.org/10.1007/s42354-021-0346-4
https://doi.org/10.1007/s42354-021-0346-4
Autor:
Mark Mattingly, Chris Seidel, Sofía Muñoz, Yan Hao, Ying Zhang, Zhihui Wen, Laurence Florens, Frank Uhlmann, Jennifer L. Gerton
The ring-like cohesin complex plays an essential role in chromosome segregation, organization, and double-strand break repair through its ability to bring two DNA double helices together. Scc2 (NIPBL in humans) together with Scc4 functions as the loa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29a96fe4d4123a3ee1f10187a26b6cb
Autor:
Zhihui Wen, Frank Uhlmann, Yan Hao, Sofía Muñoz, Chris Seidel, Laurence Florens, Ying Zhang, Mark Mattingly, Jennifer L. Gerton
Publikováno v:
SSRN Electronic Journal.
The ring-like cohesin complex plays an essential role in chromosome segregation, organization, and double-strand break repair through its ability to bring two DNA double helices together. Scc2 (NIPBL in humans) together with Scc4 function as the load
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6a62c2116fea87d471ac8dda600f5f4
https://doi.org/10.2139/ssrn.3761884
https://doi.org/10.2139/ssrn.3761884
Publikováno v:
Current Genetics. 64:1197-1203
Successful proliferation and function of an organism relies on the equal segregation of its genetic material during cell division. Duplicate sister chromatids need to accurately segregate at mitosis. Precise segregation depends on a multicomplex prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9e04ac635f0e56f74560eec6a03a297
https://doi.org/10.1007/s00294-018-0841-9
https://doi.org/10.1007/s00294-018-0841-9
Autor:
Karthik Dhatchinamoorthy, Geetha S. Hewawasam, Chris Seidel, Mark Mattingly, Jennifer L. Gerton
Publikováno v:
Nucleic Acids Research
Correct localization of the centromeric histone variant CenH3/CENP-A/Cse4 is an important part of faithful chromosome segregation. Mislocalization of CenH3 could affect chromosome segregation, DNA replication and transcription. CENP-A is often overex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50989c3efe15674080c1c8af9eaa80c1
https://doi.org/10.1093/nar/gky169
https://doi.org/10.1093/nar/gky169
Autor:
Jennifer L. Gerton, Jerry L. Workman, Mark Mattingly, Swaminathan Venkatesh, Laurence Florens, Geetha S. Hewawasam, Ying Zhang
Publikováno v:
The Journal of Biological Chemistry
Background: Psh1 is an E3 ubiquitin ligase that controls CenH3/Cse4 levels through proteolysis in budding yeast. Results: Psh1 is phosphorylated in vivo by CK2, and its E3 ligase activity is promoted. Conclusion: Phosphorylation is crucial in Psh1-as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b8264abfb52c068eab69fc906e3e0d1
https://doi.org/10.1074/jbc.m114.580589
https://doi.org/10.1074/jbc.m114.580589
Publikováno v:
The Journal of Biological Chemistry
The Cse4 nucleosome at each budding yeast centromere must be faithfully assembled each cell cycle to specify the site of kinetochore assembly and microtubule attachment for chromosome segregation. Although Scm3 is required for the localization of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c3ba4d99a8406c6e3952cfd2d9f4845
https://doi.org/10.1074/jbc.m110.183640
https://doi.org/10.1074/jbc.m110.183640