Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mark M. Wurfel, MD, PhD"'
Autor:
Vikramjit Mukherjee, MD, FRCP, Radu Postelnicu, MD, Chelsie Parker, MS, Patrick S. Rivers, PhD, George L. Anesi, MD, MSCE, MBE, Adair Andrews, RN, MATD, Erin Ables, MA, Eric D. Morrell, MD, MA, David M. Brett-Major, MD, MPH, M. Jana Broadhurst, MD, PhD, J. Perren Cobb, MD, Amy Irwin, DNP, RN, Christopher J. Kratochvil, MD, Kelsey Krolikowski, BA, Vishakha K. Kumar, MD, MBA, Douglas P. Landsittel, PhD, Richard A. Lee, MD, Janice M. Liebler, MD, Leopoldo N. Segal, MD, Jonathan E. Sevransky, MD, MHS, Avantika Srivastava, MS, Timothy M. Uyeki, MD, MPH, Mark M. Wurfel, MD, PhD, David Wyles, MD, Laura E. Evans, MD, MSc, Karen Lutrick, PhD, Pavan K. Bhatraju, MD, MSc, on behalf of the Severe Acute Respiratory Infection-Preparedness (SARI-PREP) Study Group
Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1122 (2024)
IMPORTANCE:. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has evolved through multiple phases in the United States, with significant differences in patient centered outcomes with improvements in hospital strain, medical c
Externí odkaz:
https://doaj.org/article/40d4a8c263284e60ad1b0d3e293f20b0
Autor:
Michael L. Granda, MD, MS, Frances Tian, MD, Leila R. Zelnick, PhD, Pavan K. Bhatraju, MD, MSc, Julia Hallowell, BS, Mark M. Wurfel, MD, PhD, Andrew Hoofnagle, MD, PhD, Eric Morrell, MD, Bryan Kestenbaum, MD, MS
Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1109 (2024)
IMPORTANCE:. COVID-19 may injure the kidney tubules via activation of inflammatory host responses and/or direct viral infiltration. Most studies of kidney injury in COVID-19 lacked contemporaneous controls or measured kidney biomarkers at a single ti
Externí odkaz:
https://doaj.org/article/fde3c87edc9344138e1b112383fd8ba4
Autor:
Pavan K. Bhatraju, MD, MSc, Eric D. Morrell, MD, Ian B. Stanaway, PhD, Neha A. Sathe, MD, MSc, Avantika Srivastava, MS, Radu Postelnicu, MD, Richard Green, BS, Adair Andrews, BSN, Martin Gonzalez, BS, Christopher J. Kratochvil, MD, Vishakha K. Kumar, BS, Tien-Ying Hsiang, PhD, Michael Gale, Jr, PhD, George L. Anesi, MD, David Wyles, MD, M. Jana Broadhurst, MD, PhD, David Brett-Major, MD, MPH, Vikramjit Mukherjee, MD, Jonathan E. Sevransky, MD, Douglas Landsittel, PhD, Chi Hung, MD, William A. Altemeier, MD, Sina A. Gharib, MD, Timothy M. Uyeki, MD, MPH, J. Perren Cobb, MD, Janice M. Liebler, MD, David R. Crosslin, PhD, Gail P. Jarvik, MD, Leopoldo N. Segal, MD, Laura Evans, MD, Carmen Mikacenic, MD, Mark M. Wurfel, MD, PhD
Publikováno v:
Critical Care Explorations, Vol 5, Iss 1, p e0827 (2023)
IMPORTANCE:. Vascular dysfunction and capillary leak are common in critically ill COVID-19 patients, but identification of endothelial pathways involved in COVID-19 pathogenesis has been limited. Angiopoietin-like 4 (ANGPTL4) is a protein secreted in
Externí odkaz:
https://doaj.org/article/de84ce123a564b7b9fa872a7b541c824
Autor:
F. Linzee Mabrey, MD, Pavan K. Bhatraju, MD, MSc, Eric D. Morrell, MD, Leila R. Zelnick, PhD, Neha A. Sathe, MD, Nicholas G. O’Connor, BS, Carmen Mikacenic, MD, Thomas R. Martin, MD, W. Conrad Liles, MD, PhD, Mark M. Wurfel, MD, PhD
Publikováno v:
Critical Care Explorations, Vol 4, Iss 12, p e0813 (2022)
OBJECTIVES:. To identify and characterize clinical decline after completion of dexamethasone in severe COVID-19 and determine whether interleukin (IL)-6 and other inflammatory biomarkers predict the occurrence of clinical decline. DESIGN:. Prospectiv
Externí odkaz:
https://doaj.org/article/702f096281464ae990290eca015e72e5
Autor:
F. Linzee Mabrey, MD, Leila R. Zelnick, PhD, Eric D. Morrell, MD, Nicholas G. O’Connor, BS, Andrew Hart, BA, Mark M. Wurfel, MD, PhD, W. Conrad Liles, MD, PhD, Pavan K. Bhatraju, MD, MSc
Publikováno v:
Critical Care Explorations, Vol 4, Iss 9, p e0754 (2022)
OBJECTIVES:. To determine whether the early serologic response in COVID-19 critical illness is associated with hospital mortality. To evaluate if time-to-seroconversion differs by receipt of dexamethasone therapy. DESIGN:. Patients were prospectively
Externí odkaz:
https://doaj.org/article/045d78be8b9646edaf410f124a463afc
Autor:
F. Linzee Mabrey, MD, Eric D. Morrell, MD, Pavan K. Bhatraju, MD, MSc, Neha A. Sathe, MD, Sana S. Sakr, PhD, Sharon K. Sahi, BS, T. Eoin West, MD, MPH, Carmen Mikacenic, MD, Mark M. Wurfel, MD, PhD
Publikováno v:
Critical Care Explorations, Vol 3, Iss 12, p e0591 (2021)
IMPORTANCE:. In bacterial sepsis, CD14 and its N-terminal fragment (soluble CD14 subtype, “Presepsin”) have been characterized as markers of innate immune responses and emerging evidence has linked both to coronavirus disease 2019 pathophysiology
Externí odkaz:
https://doaj.org/article/851515288e184cbe82f3d9a0e3ba8074