Zobrazeno 1 - 10
of 155
pro vyhledávání: '"Mark M. Rasenick"'
Autor:
Jeffrey M. Schappi, Mark M. Rasenick
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The relationship between depression, its etiology and therapy, and the cAMP signaling system have been studies for decades. This review will focus on cAMP, G proteins and adenylyl cyclase and depression or antidepressant action. Both human and animal
Externí odkaz:
https://doaj.org/article/b28a380fdc304048ab998cc4881afe72
Autor:
Tuba Sural-Fehr, Harinder Singh, Ludovico Cantuti-Catelvetri, Hongling Zhu, Michael S. Marshall, Rima Rebiai, Martin J. Jastrzebski, Maria I. Givogri, Mark M. Rasenick, Ernesto R. Bongarzone
Publikováno v:
Disease Models & Mechanisms, Vol 12, Iss 5 (2019)
Glycosphingolipid (GSL) accumulation is implicated in the neuropathology of several lysosomal conditions, such as Krabbe disease, and may also contribute to neuronal and glial dysfunction in adult-onset conditions such as Parkinson's disease, Alzheim
Externí odkaz:
https://doaj.org/article/8f6c1199c62d42989015042c45f8082b
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Progress toward new antidepressant therapies has been relatively slow over the past few decades, with the result that individuals suffering from depression often struggle to find an effective treatment – a process often requiring months. Furthermor
Externí odkaz:
https://doaj.org/article/19d31b84a6854445947677730d21dd64
Autor:
Steven D. Targum, Jeffrey Schappi, Athanasia Koutsouris, Runa Bhaumik, Mark H. Rapaport, Natalie Rasgon, Mark M. Rasenick
Publikováno v:
Molecular Psychiatry. 27:1640-1646
Publikováno v:
Encyclopedia of Cell Biology ISBN: 9780128216248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e98a1c75491fd3ab7f294edbef1e1be7
https://doi.org/10.1016/b978-0-12-821618-7.00123-1
https://doi.org/10.1016/b978-0-12-821618-7.00123-1
Autor:
Jeffrey M, Schappi, Mark M, Rasenick
Publikováno v:
Frontiers in pharmacology. 13
The relationship between depression, its etiology and therapy, and the cAMP signaling system have been studies for decades. This review will focus on cAMP, G proteins and adenylyl cyclase and depression or antidepressant action. Both human and animal
Autor:
Mark M. Rasenick, Nicolas B. Senese
Publikováno v:
Molecular Pharmacology. 100:96-111
Termination of antidepressant therapy often has negative consequences. Although symptoms of antidepressant withdrawal are widely recognized, the molecular processes that underlie them are not well characterized. We show that certain aspects of Gαs s
Autor:
Steven D, Targum, Jeffrey, Schappi, Athanasia, Koutsouris, Runa, Bhaumik, Mark H, Rapaport, Natalie, Rasgon, Mark M, Rasenick
Publikováno v:
Molecular psychiatry. 27(3)
In contrast to healthy controls, the heterotrimeric G protein, Gsalpha (Gsα) is ensconced predominantly in lipid rafts in subjects with major depressive disorder (MDD) resulting in impaired stimulation of adenylyl cyclase. In this small proof-of-con
Publikováno v:
The FASEB Journal. 35
Neuronal complexity is attenuated in preclinical models of migraine and restored by HDAC6 inhibition
Autor:
Zachariah Bertels, Pavel A. Petukhov, Bhargava Karumudi, Wiktor D Witkowski, Alycia F Tipton, Mark M. Rasenick, Pal Shah, Zoie Sheets, Elizaveta Mangutov, Harinder Singh, Serapio M. Baca, Amynah A. Pradhan, Isaac Dripps, Valentina Petukhova, Mei Ao, Catherine Conway, Kendra Siegersma
Publikováno v:
eLife
eLife, Vol 10 (2021)
eLife, Vol 10 (2021)
Migraine is the sixth most prevalent disease worldwide but the mechanisms that underlie migraine chronicity are poorly understood. Cytoskeletal flexibility is fundamental to neuronal-plasticity and is dependent on dynamic microtubules. Histone-deacet