Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Mark M. Neis"'
Publikováno v:
JDDG: Journal der Deutschen Dermatologischen Gesellschaft. 14:843-846
Autor:
Hans F. Merk, Mark M. Neis
Publikováno v:
Cutaneous and Ocular Toxicology. 31:117-123
Stings by insects can precipitate many signs and symptoms of dermatological and ocular diseases. Of particular importance is the anaphylaxis after Hymenoptera stings. Selection of the appropriate venom for immunotherapy requires a precise diagnosis,
Autor:
Jens M. Baron, Jörg Mey, Hans F. Merk, Ruth Heise, Sylvia Joussen, Hagen Ott, David R. Bickers, Mosaad Megahed, Mark M. Neis, T. Wiederholt, Yvonne Marquardt, Peter Kurschat
Publikováno v:
Journal of Investigative Dermatology. 126:2473-2480
Cellular levels of all-trans retinoic acid (RA) are meticulously regulated utilizing an array of systems to balance uptake, biosynthesis, catabolism, and efflux transport. Metabolic transformation of all-trans RA to 4-hydroxylated RA appears to be pr
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 319:1162-1171
Human epidermal keratinocytes express subsets of cytochromes P450 (P450) (CYP gene products) that are strongly up-regulated, not regulated, or down-regulated by differentiation-specific factors. We investigated how drug exposure affects epidermal exp
Publikováno v:
Toxicology and Applied Pharmacology. 213:135-144
Epoxyeicosatrienoic acids produced by mouse CYP2B19 have been implicated in mechanisms regulating epidermal cornification (Ladd, P.A., Du, L., Capdevila, J.H., Mernaugh, R., Keeney, D.S., 2003. Epoxyeicosatrienoic acids activate transglutaminases in
Autor:
Alexandra Dreuw, Gabriele Zwadlo-Klarwasser, Ruth Schiffer, Carsten Gartung, Mark M. Neis, Andreas Geier, Felipe Rodríguez, Hans F. Merk, Frank Lammert, Jens M. Baron, Daniela Höller, Frank K. Jugert
Publikováno v:
Journal of Investigative Dermatology. 120:285-291
Normal human epidermal keratinocytes have been shown to express a cell-type-specific pattern of extrahepatic cytochrome P450 enzymes and efflux transport proteins showing that these cells metabolize and excrete a variety of xenobiotics. Recently tran
Publikováno v:
Clinical & Experimental Allergy. 32:736-744
Background In vitro detection of drug sensitization is still limited. The lymphocyte transformation test, which determines drug-specific proliferation, is the only in vitro test for detecting drug sensitization at the cellular level irrespective of t
Autor:
Mark M. Neis
Publikováno v:
Skin Pharmacology and Physiology. 15:270-274
Autor:
Jens M. Baron, Hans F. Merk, Frank K. Jugert, Mark M. Neis, Silke Frankenberg, Daniela Höller, Ruth Schiffer
Publikováno v:
Journal of Investigative Dermatology. 116(4):541-548
Cytochrome P450 enzymes metabolize various endogenous and exogenous small molecular weight compounds. Transport-associated proteins, such as P-glycoprotein, multidrug resistance-associated protein and lung resistance protein are overexpressed in drug
Autor:
Randolf Brehler, Mark M. Neis, Ludger Klimek, Hans F. Merk, Alexander Kapp, Jochen Sieber, Regina Fölster-Holst
Publikováno v:
Expert opinion on drug safety. 11(1)
The usual build-up phase of days or weeks in allergen-specific immunotherapy entails inconveniences for individuals with symptoms only during the pollen season. Additionally, affected individuals often appear for treatment shortly before the expected