Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Mark M. Metzstein"'
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007146 (2018)
During sprouting angiogenesis in the vertebrate vascular system, and primary branching in the Drosophila tracheal system, specialized tip cells direct branch outgrowth and network formation. When tip cells lumenize, they form subcellular (seamless) t
Externí odkaz:
https://doaj.org/article/4fab9ef00b764468bc967ed3684e3017
Publikováno v:
eLife, Vol 5 (2016)
The nonsense-mediated mRNA decay (NMD) pathway functions to degrade both abnormal and wild-type mRNAs. NMD is essential for viability in most organisms, but the molecular basis for this requirement is unknown. Here we show that a single, conserved NM
Externí odkaz:
https://doaj.org/article/de95513addb34961acdcb4af11e3f7f3
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45649 (2012)
The cellular and molecular cues involved in creating branched tubular networks that transport liquids or gases throughout an organism are not well understood. To identify factors required in branching and lumen formation of Drosophila tracheal termin
Externí odkaz:
https://doaj.org/article/5ea8221815984d4096784bb6a48718e2
Autor:
Dominique Foerster, Kimberley A. Frizzell, Stefan Luschnig, Mark M. Metzstein, Jonathan O. Nelson
Publikováno v:
Genetics. 209:1073-1084
The nonsense-mediated messenger RNA (mRNA) decay (NMD) pathway is a cellular quality control and post-transcriptional gene regulatory mechanism and is essential for viability in most multicellular organisms . A complex of proteins has been identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::227bb7398a97378db91fdb69abcf89f1
https://doi.org/10.1534/genetics.118.301140
https://doi.org/10.1534/genetics.118.301140
Autor:
Mark M Metzstein, Mark A Krasnow
Publikováno v:
PLoS Genetics, Vol 2, Iss 12, p e180 (2006)
Nonsense-mediated mRNA decay (NMD) is a cellular surveillance mechanism that degrades transcripts containing premature translation termination codons, and it also influences expression of certain wild-type transcripts. Although the biochemical mechan
Externí odkaz:
https://doaj.org/article/5a1f68779f5c4b50bf10877287cb1bfe
Autor:
Jonathan O, Nelson, Dominique, Förster, Kimberly A, Frizzell, Stefan, Luschnig, Mark M, Metzstein
Publikováno v:
Genetics. 209(4)
The nonsense-mediated messenger RNA (mRNA) decay (NMD) pathway is a cellular quality control and post-transcriptional gene regulatory mechanism and is essential for viability in most multicellular organisms . A complex of proteins has been identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3e0194819dde36f2286abc038119cc4e
https://pubmed.ncbi.nlm.nih.gov/29903866
https://pubmed.ncbi.nlm.nih.gov/29903866
Autor:
Mark M. Metzstein, Jonathan O. Nelson
Publikováno v:
mRNA Decay ISBN: 9781493975396
Transcriptome analysis provides a snapshot of cellular gene expression and is used to determine how cells and organisms respond to genetic or environmental changes. Identifying the transcripts whose expression levels are regulated directly by the man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28da642ea177794e316f03419bfcd615
https://doi.org/10.1007/978-1-4939-7540-2_15
https://doi.org/10.1007/978-1-4939-7540-2_15
Autor:
Jonathan O, Nelson, Mark M, Metzstein
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1720
Transcriptome analysis provides a snapshot of cellular gene expression and is used to determine how cells and organisms respond to genetic or environmental changes. Identifying the transcripts whose expression levels are regulated directly by the man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a1983430651094500194d51092107fcd
https://pubmed.ncbi.nlm.nih.gov/29236261
https://pubmed.ncbi.nlm.nih.gov/29236261
Autor:
Stefan Luschnig, Dominique Foerster, Jonathan O. Nelson, Mark M. Metzstein, Kimberley A. Frizzell
The nonsense-mediated mRNA decay (NMD) pathway is a cellular quality control and post-transcriptional gene regulatory mechanism and is essential for viability in most multicellular organisms. A complex of proteins has been identified to be required f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1726eb6fa2b9d4493b7ac557feb8651e
https://doi.org/10.1101/219725
https://doi.org/10.1101/219725
Publikováno v:
eLife, Vol 5 (2016)
The nonsense-mediated mRNA decay (NMD) pathway functions to degrade both abnormal and wild-type mRNAs. NMD is essential for viability in most organisms, but the molecular basis for this requirement is unknown. Here we show that a single, conserved NM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1752135375106bac0cee2ff19f06e1c4
https://doi.org/10.7554/elife.12876
https://doi.org/10.7554/elife.12876