Zobrazeno 1 - 10
of 134
pro vyhledávání: '"Mark M. Kushnir"'
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 21, Iss , Pp 19-26 (2021)
Introduction: Diagnosis of pheochromocytoma and paraganglioma (PPGL) is aided by the measurement of metanephrine (MN) and normetanephrine (NMN). Research suggests that 3-methoxytyramine (3MT), a dopamine (DA) metabolite, may serve as a biomarker of m
Externí odkaz:
https://doaj.org/article/1eaa0ce312314b99991eb55f22599485
Autor:
Amol O. Bajaj, Mark M. Kushnir, Erik Kish-Trier, Rachel N. Law, Lauren M. Zuromski, Alejandro R. Molinelli, Gwendolyn A. McMillin, Kamisha L. Johnson-Davis
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Monitoring concentrations of thiopurine metabolites is used clinically to prevent adverse effects in patients on thiopurine drug therapy. We developed a LC–MS/MS method for the quantification of 6-thioguanine (6-TG) and 6-methylmercaptopurine (6-MM
Externí odkaz:
https://doaj.org/article/407776749862488c874a8022e8f47d7e
Publikováno v:
Journal of Proteome Research.
Autor:
Yingya Zhao, Yu‐Tang Gao, Xianglan Zhang, Alan L. Rockwood, Mark M. Kushnir, Qiuyin Cai, Jie Wu, Jiajun Shi, Qing Lan, Nathaniel Rothman, Yu Shyr, Xiao‐Ou Shu, Wei Zheng, Gong Yang
Publikováno v:
International Journal of Cancer. 151:699-707
Although reproductive factors have been repeatedly associated with lung cancer risk, no study to date has directly evaluated the relationship with endogenous sex hormones nor with aromatase activity in postmenopausal never-smoking women. A case-contr
Publikováno v:
Journal of proteome research.
Elevated serum alpha-fetoprotein (AFP) can be observed in liver cirrhosis and hepatocellular carcinoma (HCC). The glycosylation patterns of AFP have been shown to differentiate these conditions, with AFP glycoforms with core fucosylation (AFP-L3) ser
Publikováno v:
Journal of Mass Spectrometry and Advances in the Clinical Lab, Vol 21, Iss, Pp 19-26 (2021)
Journal of Mass Spectrometry and Advances in the Clinical Lab
Journal of Mass Spectrometry and Advances in the Clinical Lab
Graphical abstract
Highlights • 3-methoxytyramine (3MT) aids diagnosis of dopamine-producing tumors and metastases. • A sensitive and specific LC-MS/MS method was developed to measure 3MT in plasma. • 3MT was elevated in 46% of samples wit
Highlights • 3-methoxytyramine (3MT) aids diagnosis of dopamine-producing tumors and metastases. • A sensitive and specific LC-MS/MS method was developed to measure 3MT in plasma. • 3MT was elevated in 46% of samples wit
Autor:
Mark M, Kushnir, Alan L, Rockwood
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2546
N-terminal sequence of parathyroid hormone-related protein (PTHrP) has close homology to parathyroid hormone (PTH). In health, both PTH and PTHrP participate in calcium regulation and homeostasis, but some of the functions, such as regulation of bone
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2546
Measurement of methylmalonic acid (MMA) plays an important role in the diagnosis of vitamin B
Autor:
Yingya Zhao, Xiao-Ou Shu, Yu-Tang Gao, Mark M. Kushnir, Qiuyin Cai, Hui Cai, Qing Lan, Nathaniel Rothman, Wei Zheng, Gong Yang
Publikováno v:
Cancer Research. 83:6491-6491
Background: Exogenous sex hormone supplements had been associated with increased lung cancer mortality in a large clinical trial. No study to date has evaluated temporal trajectories of circulating sex hormones and aromatase activity and their associ
Autor:
Cora M. Best, Kenneth E. Thummel, Simon Hsu, Yvonne Lin, Leila R. Zelnick, Bryan Kestenbaum, Mark M. Kushnir, Ian H. de Boer, Andrew N. Hoofnagle
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 226:106206