Zobrazeno 1 - 10
of 296
pro vyhledávání: '"Mark M. Goodman"'
Autor:
Ephraim E. Parent, Dhruv Patel, Jonathon A. Nye, Zhuo Li, Jeffrey J. Olson, David M. Schuster, Mark M. Goodman
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract Background Stereotactic radiosurgery (SRS) is often the primary treatment modality for patients with intracranial metastatic disease. Despite advances in magnetic resonance imaging, including use of perfusion and diffusion sequences and mole
Externí odkaz:
https://doaj.org/article/d7ff5e2e51cb449fa3d40041325c3f10
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
The serotonin 5-HT2C receptor (5-HT2CR) is abundantly expressed throughout the central nervous system, and involved in a variety of neuroendocrine and neurobehavioral processes. The development of a selective radioligand that will enable in vivo imag
Externí odkaz:
https://doaj.org/article/069f82e0d7c44debaea12f523363efe6
Autor:
Valerie Joers, Gunasingh Masilamoni, Doty Kempf, Alison R. Weiss, Travis M. Rotterman, Benjamin Murray, Gul Yalcin-Cakmakli, Ronald J. Voll, Mark M. Goodman, Leonard Howell, Jocelyne Bachevalier, Stefan J. Green, Ankur Naqib, Maliha Shaikh, Phillip A. Engen, Ali Keshavarzian, Christopher J. Barnum, Jonathon A. Nye, Yoland Smith, Malú G. Tansey
Publikováno v:
Neurobiology of Disease, Vol 144, Iss , Pp 105027- (2020)
Inflammation has been linked to the development of nonmotor symptoms in Parkinson's disease (PD), which greatly impact patients' quality of life and can often precede motor symptoms. Suitable animal models are critical for our understanding of the me
Externí odkaz:
https://doaj.org/article/43c19177d7114cb980da723d241e3f02
Autor:
Ephraim E. Parent, Marc Benayoun, Ijeoma Ibeanu, Jeffrey J. Olson, Constantinos G. Hadjipanayis, Daniel J. Brat, Vikram Adhikarla, Jonathon Nye, David M. Schuster, Mark M. Goodman
Publikováno v:
EJNMMI Research, Vol 8, Iss 1, Pp 1-11 (2018)
Abstract Background The ability to accurately and non-invasively distinguish high-grade glioma from low-grade glioma remains a challenge despite advances in molecular and magnetic resonance imaging. We investigated the ability of fluciclovine (18F) P
Externí odkaz:
https://doaj.org/article/4fd89adff58342b8944419ace6ce1fb3
Autor:
Thyagarajan Subramanian M.D., Dwaine F. Emerich, Roy A. E. Bakay, John M. Hoffman, Mark M. Goodman, Timothy M. Shoup, Gary W. Miller, Allan I. Levey, George W. Hubert, Scott Batchelor, Shelly R. Winn, Joel A. Saydoff, Ray L. Watts
Publikováno v:
Cell Transplantation, Vol 6 (1997)
Intracranial implantation of polymer-encapsulated PC-12 cells has been shown to improve motor behavioral performance in animal models of Parkinson's disease. The purpose of this blinded study was to examine whether such improvement is associated with
Externí odkaz:
https://doaj.org/article/1c81fb28e8a641d18445c4b76ba7e66b
Autor:
Erwin G. Van Meir, K.C. Nicolaou, Mark M. Goodman, Ruiwen Zhang, Jeffrey J. Olson, Zhengjia Chen, Thomas Abbruscato, Zhibo Wang, Wei Wang, Purushotham R. Boreddy, Zhaobin Zhang, Jiyoung Mun, Rita G. de Noronha, Adnan A. Jabbar, Narra S. Devi, Stefan Kaluz, Shaoman Yin
PDF file, 285K, Supplementary Figure 1. Synthetic scheme and purity of KCN1 3,4-dimethoxy-N-(2,2-dimethyl-2H-chromen-6-yl)methyl-N-phenylbenzenesulfonamide. Supplementary Figure 2. KCN1 is chemically stable in cell culture medium under normoxic or hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a5604fa82bef743c03483a070486941
https://doi.org/10.1158/1078-0432.22451897.v1
https://doi.org/10.1158/1078-0432.22451897.v1
Autor:
Erwin G. Van Meir, K.C. Nicolaou, Mark M. Goodman, Ruiwen Zhang, Jeffrey J. Olson, Zhengjia Chen, Thomas Abbruscato, Zhibo Wang, Wei Wang, Purushotham R. Boreddy, Zhaobin Zhang, Jiyoung Mun, Rita G. de Noronha, Adnan A. Jabbar, Narra S. Devi, Stefan Kaluz, Shaoman Yin
Purpose: The hypoxia-inducible factor-1 (HIF-1) plays a critical role in tumor adaptation to hypoxia, and its elevated expression correlates with poor prognosis and treatment failure in patients with cancer. In this study, we determined whether 3,4-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb323e17c5a0b8e7a7bc068b430613e
https://doi.org/10.1158/1078-0432.c.6522323
https://doi.org/10.1158/1078-0432.c.6522323
Autor:
Erwin G. Van Meir, K.C. Nicolaou, Mark M. Goodman, Ruiwen Zhang, Jeffrey J. Olson, Zhengjia Chen, Thomas Abbruscato, Zhibo Wang, Wei Wang, Purushotham R. Boreddy, Zhaobin Zhang, Jiyoung Mun, Rita G. de Noronha, Adnan A. Jabbar, Narra S. Devi, Stefan Kaluz, Shaoman Yin
PDF file, 106K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e87de02930b9a303fe64ab33cfcc548
https://doi.org/10.1158/1078-0432.22451900
https://doi.org/10.1158/1078-0432.22451900
Autor:
Erwin G. Van Meir, K.C. Nicolaou, Mark M. Goodman, Ruiwen Zhang, Jeffrey J. Olson, Zhengjia Chen, Thomas Abbruscato, Zhibo Wang, Wei Wang, Purushotham R. Boreddy, Zhaobin Zhang, Jiyoung Mun, Rita G. de Noronha, Adnan A. Jabbar, Narra S. Devi, Stefan Kaluz, Shaoman Yin
PDF file, 591K, Supplementary Figure 4. KCN1 inhibits the growth of pre-established human glioblastoma s.c. xenografts. Supplementary Figure 5. Effect of KCN1 treatment on mice weight. Supplementary Figure 6. Chronic systemic KCN1 administration show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3746120f1e5c5a2e32f51772ecf87422
https://doi.org/10.1158/1078-0432.22451894.v1
https://doi.org/10.1158/1078-0432.22451894.v1
Autor:
Erwin G. Van Meir, K.C. Nicolaou, Mark M. Goodman, Ruiwen Zhang, Jeffrey J. Olson, Zhengjia Chen, Thomas Abbruscato, Zhibo Wang, Wei Wang, Purushotham R. Boreddy, Zhaobin Zhang, Jiyoung Mun, Rita G. de Noronha, Adnan A. Jabbar, Narra S. Devi, Stefan Kaluz, Shaoman Yin
PDF file, 88K.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f8fd2d26142ed98929ae33bafcd3659
https://doi.org/10.1158/1078-0432.22451891.v1
https://doi.org/10.1158/1078-0432.22451891.v1