Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mark M Mahoney"'
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172677 (2017)
Rodent organotypic hippocampal cultures spontaneously develop epileptiform activity after approximately 2 weeks in vitro and are increasingly used as a model of chronic post-traumatic epilepsy. However, organotypic cultures are maintained in an artif
Externí odkaz:
https://doaj.org/article/39be02068a53497abdd0a240baf69dfa
Autor:
Marija Usenovic, Yero Saponjian, Kevin J. Staley, Yevgeny Berdichevsky, Mark M. Mahoney, Corrin A. Pimentel, Alexandra M. Dryer, Corrina A. Lucini
Publikováno v:
The Journal of Neuroscience. 33:9056-9067
mTOR is activated in epilepsy, but the mechanisms of mTOR activation in post-traumatic epileptogenesis are unknown. It is also not clear whether mTOR inhibition has an anti-epileptogenic, or merely anticonvulsive effect. The rat hippocampal organotyp
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 2, p e0172677 (2017)
PLoS ONE, Vol 12, Iss 2, p e0172677 (2017)
Rodent organotypic hippocampal cultures spontaneously develop epileptiform activity after approximately 2 weeks in vitro and are increasingly used as a model of chronic post-traumatic epilepsy. However, organotypic cultures are maintained in an artif