Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Mark Leggas"'
Autor:
Amelia D. Dunn, Shivon A. Robinson, Chiso Nwokafor, Molly Estill, Julia Ferrante, Li Shen, Crystal O. Lemchi, Jordi Creus-Muncunill, Angie Ramirez, Juliet Mengaziol, Julia K. Brynildsen, Mark Leggas, Jamie Horn, Michelle E. Ehrlich, Julie A. Blendy
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
IntroductionInfants exposed to opioids in utero are at high risk of exhibiting Neonatal Opioid Withdrawal Syndrome (NOWS), a combination of somatic withdrawal symptoms including high pitched crying, sleeplessness, irritability, gastrointestinal distr
Externí odkaz:
https://doaj.org/article/5c02e79f5cd44978b1bd5dd7551f72ee
Publikováno v:
Electronic Journal of Differential Equations, Vol Conference, Iss 03, Pp 39-50 (2000)
Of concern are suspension flows. These combine directed and random motions and are typically modelled by parabolic partial differential equations. Sometimes they can be better modelled (in terms of fitting the data generated by certain blood flow exp
Externí odkaz:
https://doaj.org/article/973e6a6b5d894b258763eaebbc246370
Autor:
Lars M. Wagner, James I. Geller, Jeffrey A. Bacha, Mark Leggas, Dennis Brown, Sarath Kanekal, Neil Sankar
Publikováno v:
Cancer Research. 80:CT137-CT137
Background: Ewing's sarcoma (EWS) is the second most common malignant bone tumor affecting children, adolescents and young adults. Intravenous irinotecan hydrochloride (IRN-IV) is approved for the treatment of adult colorectal cancer. IRN-IV is also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa431065656a9bae48458bcf72f67ad0
https://doi.org/10.1158/1538-7445.am2020-ct137
https://doi.org/10.1158/1538-7445.am2020-ct137
Publikováno v:
Volume 1C, Symposia: Gas-Liquid Two-Phase Flows; Gas and Liquid-Solid Two-Phase Flows; Numerical Methods for Multiphase Flow; Turbulent Flows: Issues and Perspectives; Flow Applications in Aerospace; Fluid Power; Bio-Inspired Fluid Mechanics; Flow Manipulation and Active Control; Fundamental Issues and Perspectives in Fluid Mechanics; Transport Phenomena in Energy Conversion From Clean and Sustainable Resources; Transport Phenomena in Materials Processing and Manufacturing Processes.
Theory of molecular Taylor-Aris dispersion (TAD) is an accepted framework describing tracer dispersion in suspension flows and determining effective diffusion coefficients. Our group reported a pseudo-Lagrangian method to study dispersion in suspensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e26a025faac29ef4924af7ace350d66d
https://doi.org/10.1115/fedsm2017-69549
https://doi.org/10.1115/fedsm2017-69549
Autor:
Mark Leggas, Kari Chansky, Maurice Willis, Rachel E. Sanborn, Susanne M. Arnold, Michael A. Thompson, Joseph Grant F Rosales, Saiama N. Waqar, John T. Hamm, Maria Q. Baggstrom, John L. Villano, John Crowley
Publikováno v:
Journal of Clinical Oncology. 37:8513-8513
8513 Background: Relapsed small cell lung cancer (SCLC) is incurable with limited therapeutic options. This phase II study evaluated efficacy and tolerability of carfilzomib + irinotecan in SCLC pts who progressed after prior platinum-based therapy,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::160fbcbb0fdb4d10e39cde02ef33fc31
https://doi.org/10.1200/jco.2019.37.15_suppl.8513
https://doi.org/10.1200/jco.2019.37.15_suppl.8513
Autor:
Yao Wang, Wenchen Zhao, Kelli L. Boyd, Satish Cheepala, Mark Leggas, Raman Venkataramanan, Masashi Adachi, Jessica A. Morgan, Geoff Neale, Deepa Nachagari, John D. Schuetz
Publikováno v:
Journal of Biological Chemistry. 287:14456-14466
The physiological role of multidrug resistance protein 4 (Mrp4, Abcc4) in the testes is unknown. We found that Mrp4 is expressed primarily in mouse and human Leydig cells; however, there is no current evidence that Mrp4 regulates testosterone product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d6ad2cf33ad0634d1e94db45242d4d
https://doi.org/10.1074/jbc.m111.319681
https://doi.org/10.1074/jbc.m111.319681
Autor:
Heidi L. Weiss, Susanne M. Arnold, John L. Villano, Vivek M. Rangnekar, Mark Leggas, Peng Wang
Publikováno v:
Journal of Clinical Oncology. 36:e14555-e14555
e14555Background: Prostate apoptosis response-4 (Par-4, also called PAWR) is a tumor suppressor that induces apoptosis in diverse cancer cells but not in normal cells. The baseline levels of Par-4 ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a7891cde3634d826ee6f08e4fbb01ad
https://doi.org/10.1200/jco.2018.36.15_suppl.e14555
https://doi.org/10.1200/jco.2018.36.15_suppl.e14555
Autor:
Michael A. Brooks, Elizabeth Kvale, Goetz H. Kloecker, Thomas Baeker, John Rinehart, Stacey Slone, Muhammad Ali Zaydan, Brent J. Shelton, Mark Leggas, Allen Lim, Susanne M. Arnold, Jessica Croley, Harry Carloss, Jewraj G. Maheshwari
Publikováno v:
Cancer chemotherapy and pharmacology. 71(5)
Pre-clinical and early-phase clinical studies have demonstrated that dexamethasone (DEX) administration prior to chemotherapy reduces toxicity and enhances efficacy in the treatment of cancer. We undertook a randomized, phase II multi-institutional t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab4dfa8ce6d1be003d34464e7dea3d90
https://pubmed.ncbi.nlm.nih.gov/23475103
https://pubmed.ncbi.nlm.nih.gov/23475103
Autor:
John D. Schuetz, Masashi Adachi, Deepa Nachagari, Satish Cheepala, Mark Leggas, Yao Wang, Kelli L. Boyd, Jessica A. Morgan, Geoff Neale
Publikováno v:
The FASEB Journal. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9882567bb2840501dab034c9dc1aee8b
https://doi.org/10.1096/fasebj.26.1_supplement.1047.8
https://doi.org/10.1096/fasebj.26.1_supplement.1047.8
Autor:
Jiakun Zhang, Michael A. Dyer, Mary V. Relling, Nikia A. Laurie, Jonathan Gray, Merrill J. Egorin, Mark Leggas, Clinton F. Stewart
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 11(20)
Chemotherapy combined with laser therapy and cryotherapy has improved the ocular salvage rate for children with bilateral retinoblastoma. However, children with late-stage disease often experience recurrence shortly after treatment. To improve the vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7544e88c72dd25f2518a33bb1809e48
https://pubmed.ncbi.nlm.nih.gov/16243833
https://pubmed.ncbi.nlm.nih.gov/16243833