Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Mark Laws"'
Autor:
Aqeel Imran, Muhammad Tariq Shehzad, Syed Jawad Ali Shah, Taha al Adhami, Mark Laws, Khondaker Miraz Rahman, Rima D. Alharthy, Imtiaz Ali Khan, Zahid Shafiq, Jamshed Iqbal
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract The role of aldose reductase (ALR2) in causing diabetic complications is well-studied, with overactivity of ALR2 in the hyperglycemic state leading to an accumulation of intracellular sorbitol, depletion of cytoplasmic NADPH and oxidative st
Externí odkaz:
https://doaj.org/article/0106aa7ebb294d669ddf88890a2c56a9
Autor:
Anne Ammerdorffer, Mark Laws, Arinze Awiligwe, Florence Erb, Wallada Im-Amornphong, A. Metin Gülmezoglu, Lester Chinery, Briana Lucido, Manjulaa Narasimhan
Publikováno v:
Health Research Policy and Systems, Vol 19, Iss S1, Pp 1-9 (2021)
Abstract The World Health Organization 2019 WHO consolidated guideline on self-care interventions for health: sexual and reproductive health and rights includes recommendations on self-administration of injectable contraception, over-the-counter (OTC
Externí odkaz:
https://doaj.org/article/808d26eea5324cdaa0b9bb130b202df2
Autor:
Mark Laws, Charlotte Hind, Andrea Favaron, Shirin Jamshidi, Bonnie Evans, Melanie Clifford, J. Mark Sutton, Khondaker Miraz Rahman
Publikováno v:
ACS Omega, Vol 5, Iss 21, Pp 11923-11934 (2020)
Externí odkaz:
https://doaj.org/article/dc7c8a3e0fbd4617842d4d7aec27052c
Autor:
Pietro Picconi, Rose Jeeves, Christopher William Moon, Shirin Jamshidi, Kazi S. Nahar, Mark Laws, Joanna Bacon, Khondaker Miraz Rahman
Publikováno v:
ACS Omega, Vol 4, Iss 25, Pp 20873-20881 (2019)
Externí odkaz:
https://doaj.org/article/9de31c2768a84d30bc41b6d170ca0285
Publikováno v:
Molecules, Vol 26, Iss 10, p 2943 (2021)
Antibody–drug conjugates (ADCs) are a family of targeted therapeutic agents for the treatment of cancer. ADC development is a rapidly expanding field of research, with over 80 ADCs currently in clinical development and eleven ADCs (nine containing
Externí odkaz:
https://doaj.org/article/7da426bbdf6847f5858cb9c22bd39f84
Autor:
Aqeel Imran, Muhammad Tariq Shehzad, Syed Jawad Ali Shah, Mark Laws, Taha al-Adhami, Khondaker Miraz Rahman, Imtiaz Ali Khan, Zahid Shafiq, Jamshed Iqbal
Publikováno v:
ACS Omega. 7:26425-26436
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cd3a7686539d79bcbda8977291bf1d6
https://doi.org/10.1021/acsomega.2c02326
https://doi.org/10.1021/acsomega.2c02326
Publikováno v:
Drug Discovery Today. 27:354-361
In antibody–drug conjugates (ADCs), monoclonal antibodies (mAbs) act as carriers for a cytotoxic payload providing the therapy with targeted action against cells expressing a target cell surface antigen. An appropriate choice of mAb is crucial to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0fb4f01fb4dc65ff26fbe926aadd0ca
https://doi.org/10.1016/j.drudis.2021.09.015
https://doi.org/10.1016/j.drudis.2021.09.015
Autor:
Khondaker M. Rahman, Andrea Favaron, Shirin Jamshidi, Melanie Clifford, Mark Laws, Charlotte K. Hind, J. Mark Sutton, Bonnie Evans
Publikováno v:
Laws, M, Hind, C K, Favoran, A, Jamshidi, S, Evans, B, Clifford, M, Mark Sutton, J & Rahman, M 2020, ' N1-Benzofused Modification of Fluoroquinolones Reduces Activity Against Gram-Negative Bacteria ', ACS Omega, vol. 5, no. 21, acsomega.9b03910, pp. 11923–11934 . https://doi.org/10.1021/acsomega.9b03910
ACS Omega, Vol 5, Iss 21, Pp 11923-11934 (2020)
ACS Omega
ACS Omega, Vol 5, Iss 21, Pp 11923-11934 (2020)
ACS Omega
The fluoroquinolone class of antibiotics has a well-established structure-activity relationship (SAR) and a long history in the clinic, but the effect of electron-rich benzofused substituents at the N1 position remains poorly explored. Because groups
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdaa060096282972ab456f1b9b8a5e4d
https://doi.org/10.1021/acsomega.9b03910
https://doi.org/10.1021/acsomega.9b03910
Autor:
Anne Ammerdorffer, Mark Laws, Manjulaa Narasimhan, Briana Lucido, Agnes Kijo, Lale Say, Arinze Awiligwe, Lester Chinery, A Metin Gülmezoglu
Publikováno v:
Bulletin of the World Health Organization. 100(8)
Self-care interventions include over-the-counter contraceptives, which enable individuals to make informed, autonomous decisions about fertility management. As there is a substantial unmet need for contraception in many countries, increasing access b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c5716e30bf0852a8d278890f84ec62e
https://pubmed.ncbi.nlm.nih.gov/35923274
https://pubmed.ncbi.nlm.nih.gov/35923274
Autor:
Joanna Bacon, Christopher William Moon, Khondaker M. Rahman, Rose E. Jeeves, Shirin Jamshidi, Pietro Picconi, Mark Laws, Kazi S. Nahar
Publikováno v:
ACS Omega, Vol 4, Iss 25, Pp 20873-20881 (2019)
The development of new antitubercular agents for the treatment of infections caused by multidrug-resistant (MDR) Mycobacterium tuberculosis is an urgent priority. Pyrrolobenzodiazepines (PBDs) are a promising class of antibacterial agents that were i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d690a6dd6b9fc98a68145f91ee3a957
https://doi.org/10.1021/acsomega.9b00834
https://doi.org/10.1021/acsomega.9b00834