Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Mark L. Thompson"'
Autor:
Matthew R, Bennett, Mark L, Thompson, Sarah A, Shepherd, Mark S, Dunstan, Abigail J, Herbert, Duncan R M, Smith, Victoria A, Cronin, Binuraj R K, Menon, Colin, Levy, Jason, Micklefield
Publikováno v:
Angewandte Chemie (International Ed. in English)
Benzylisoquinoline alkaloids (BIAs) are a structurally diverse family of plant secondary metabolites, which have been exploited to develop analgesics, antibiotics, antitumor agents, and other therapeutic agents. Biosynthesis of BIAs proceeds via a co
Autor:
C. V. Karthikeyan, Mark L. Thompson, Colin Levy, Binuraj R. K. Menon, David Leys, Matthew Q. Styles, Sarah A. Shepherd, Anna-Winona Struck, Jonathan Latham, Jason Micklefield
Publikováno v:
Shepherd, S, Chinnan Velmurugan, K, Latham, J, Struck, A-W, Thompson, M, Menon, B, Styles, M, Levy, C, Leys, D & Micklefield, J 2015, ' Extending the Biocatalytic Scope of Regiocomplementary Flavin-Dependent Halogenase Enzymes ', Chemical Science, vol. 6, pp. 3454-3460 . https://doi.org/10.1039/C5SC00913H
Flavin-dependent halogenases are potentially valuable biocatalysts for the regioselective halogenation of aromatic compounds. These enzymes, utilising benign inorganic halides, offer potential advantages over traditional non-enzymatic halogenation ch
Autor:
Mark L. Thompson
This book is an account of the ships that have borne the name'Queen of the Lakes,'an honorary title indicating that, at the time of its launching, a ship is the longest on the Great Lakes. In one of the most comprehensive books ever written on the ma
Autor:
Mark L. Thompson
Steamboats and Sailors of the Great Lakestraces the evolution of the Great Lakes shipping industry over the last three centuries. The Great Lakes shipping industry can trace its lineage to 1679 with the launching on Lake Erie of the Griffon, a sixty-
Autor:
Mark L. Thompson, Ioannis V. Pavlidis, Uwe T. Bornscheuer, Markus Gall, Marlen Schmidt, Alberto Nobili
Publikováno v:
FEBS Journal. 280:3084-3093
Two libraries of simultaneous double mutations in the active site region of an esterase from Bacillus stearothermophilus were constructed to improve the enantioselectivity in the hydrolysis of tetrahydrofuran-3-yl acetate. As screening of large mutan
Publikováno v:
ChemBioChem. 13:2642-2655
S-adenosyl methionine (SAM) is a universal biological cofactor that is found in all branches of life where it plays a critical role in the transfer of methyl groups to various biomolecules, including DNA, proteins and small-molecule secondary metabol
Autor:
Brian J. C. Law, Mark L. Thompson, Sarah A. Shepherd, Jason Micklefield, David Leys, Colin Levy, Matthew R. Bennett
Publikováno v:
Law, B, Bennett, M, Thompson, M, Levy, C, Shepherd, S, Leys, D & Micklefield, J 2016, ' Effects of Active-Site Modification and Quaternary Structure on the Regioselectivity of Catechol-O-Methyltransferase. ', Angewandte Chemie (International ed. in English), vol. 55, pp. 2683–2687 . https://doi.org/10.1002/anie.201508287
Angewandte Chemie (International Ed. in English)
Angewandte Chemie (International Ed. in English)
Catechol‐O‐methyltransferase (COMT), an important therapeutic target in the treatment of Parkinson's disease, is also being developed for biocatalytic processes, including vanillin production, although lack of regioselectivity has precluded its m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cf92073cfbfa88d0da6342ae144f60b
https://doi.org/10.1002/anie.201508287
https://doi.org/10.1002/anie.201508287
Publikováno v:
Journal of Basic Microbiology. 53:509-517
Expression of phenol oxidases (PO) in bacteria is often observed during physiological and morphological changes; in the nitrogen-fixing strain Azotobacter chroococcum SBUG 1484, it is accompanied by the formation of encysted cells and melanin. Herein
Autor:
Mark L. Thompson, Kristian Geitner, Marlen Schmidt, Uwe T. Bornscheuer, Lea Talmann, Maria Kadow, Stefan Saß, Dominique Böttcher
Publikováno v:
Tetrahedron. 68:7575-7580
An assay for the spectrophotometric determination of Baeyer–Villiger monooxygenase (BVMO) activity is described. Baeyer–Villiger oxidation of p-nitroacetophenone generates the corresponding acetate and subsequent hydrolysis of this ester by an es
Autor:
Ben Meijrink, David Schmid, F. Özde Ütkür, René Ullrich, Oreste Ghisalba, Annina Riepp, Jan-Metske van der Laan, Richard Kerkman, Gideon Grogan, Andreas Schmid, Christoph Brandenbusch, Matthias Kittelmann, Jürgen Kühnöl, Stephan Luetz, Jonathan Collins, Andreas Fredenhagen, Matthias Kinne, Anton Kuhn, Bruno Bühler, Martin Hofrichter, Gabriele Sadowski, Mark L. Thompson, Marzena Poraj-Kobielska, David Mangan, Marco A. van den Berg, Antonio Osorio-Lozada, Marcus Hans, Wibo B. van Scheppingen, Thomas S. Moody, Lukas Oberer
Publikováno v:
Practical Methods for Biocatalysis and Biotransformations 2