Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Mark L. Stahl"'
Autor:
M. James Turner, Lee D. Jennings, Ann Aulabaugh, Derek Cecil Cole, E.S. Manas, Mohani N. Sukhdeo, Steve Jacobsen, Joseph Raymond Stock, Laura Lin, James Strand, Junjun Wu, Mark L. Stahl, John W. Ellingboe, Guixan Jin, and Ping Zhou, Kristi Fan, Boyd L. Harrison, Rajiv Chopra, Kristine Svenson, Frank E. Lovering, Yun Hu, Erik Wagner, Jeffrey Scott Condon, Rebecca Cowling, Michael S. Malamas, Jonathan A. Bard
Publikováno v:
Journal of Medicinal Chemistry. 49:6158-6161
BACE1 is an aspartyl protease responsible for cleaving amyloid precursor protein to liberate Abeta, which aggregates leading to plaque deposits implicated in Alzheimer's disease. We have identified small-molecule acylguanidine inhibitors of BACE1. Cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd4ec479fdb92bb1e29c0bef451eeb32
https://doi.org/10.1021/jm0607451
https://doi.org/10.1021/jm0607451
