Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Mark L. Johnson"'
Osteocyte Wnt/β-catenin pathway activation upon mechanical loading is altered in ovariectomized mice
Autor:
Erica Jackson, Nuria Lara-Castillo, Mohammed P. Akhter, Mark Dallas, JoAnna M. Scott, Thiagarajan Ganesh, Mark L. Johnson
Publikováno v:
Bone Reports, Vol 15, Iss , Pp 101129- (2021)
Estrogen levels decline in both sexes with age, but more dramatically in females. Activation of the Wnt/β-catenin signaling pathway is central to the regulation of bone mass accrual and maintenance and in response to mechanical loading. Using the ov
Externí odkaz:
https://doaj.org/article/2a032dfe8d8b4b2d88b9ef33de850cf2
Autor:
Hammad Mumtaz, Mark Dallas, Mark Begonia, Nuria Lara-Castillo, JoAnna M. Scott, Mark L. Johnson, Thiagarajan Ganesh
Publikováno v:
Bone Reports, Vol 12, Iss , Pp 100266- (2020)
Aging is known to reduce bone quality and bone strength. We sought to determine how aging affects the biomechanical and architectural properties of various long bones, and if sex influences age related differences/changes. While researchers have exte
Externí odkaz:
https://doaj.org/article/62869c1cbc7244288b4aa9b2c84c0c6f
Autor:
Sravan K. Kola, Mark T. Begonia, LeAnn M. Tiede-Lewis, Loretta E. Laughrey, Sarah L. Dallas, Mark L. Johnson, Thiagarajan Ganesh
Publikováno v:
Bone Reports, Vol 12, Iss , Pp 100277- (2020)
Osteocytes are thought to be the primary mechanosensory cells within bone, regulating both osteoclasts and osteoblasts to control load induced changes in bone resorption and formation. Osteocytes initiate intracellular responses including activating
Externí odkaz:
https://doaj.org/article/6804220407664fdbae8e16a44d4b539e
Autor:
Amber Rath Stern, Xiaomei Yao, Yong Wang, Amanuel Berhe, Mark Dallas, Mark L. Johnson, Wei Yao, Donald B. Kimmel, Nancy E. Lane
Publikováno v:
Bone Reports, Vol 8, Iss , Pp 115-124 (2018)
Though osteoporosis is a significant cause of disability worldwide, treatment with pharmacologic agents decreases risk of fragility fracture. Though these treatments act through the bone remodeling system to improve bone mass, it is unclear if they a
Externí odkaz:
https://doaj.org/article/3cd125d351134d8ba2f45f54ab52ed6f
Autor:
Tarak Srivastava, Daniel P. Heruth, R. Scott Duncan, Mohammad H. Rezaiekhaligh, Robert E. Garola, Lakshmi Priya, Jianping Zhou, Varun C. Boinpelly, Jan Novak, Mohammed Farhan Ali, Trupti Joshi, Uri S. Alon, Yuexu Jiang, Ellen T. McCarthy, Virginia J. Savin, Ram Sharma, Mark L. Johnson, Mukut Sharma
Publikováno v:
Cells, Vol 10, Iss 5, p 1253 (2021)
Increased fluid flow shear stress (FFSS) in solitary kidney alters podocyte function in vivo. FFSS-treated cultured podocytes show upregulated AKT-GSK3β-β-catenin signaling. The present study was undertaken to confirm (i) the activation of β-caten
Externí odkaz:
https://doaj.org/article/139480b8633946dea02847cfd6a4c0e9
Autor:
Yukiko, Kitase, Julian A, Vallejo, Sarah L, Dallas, Yixia, Xie, Mark, Dallas, LeAnn, Tiede-Lewis, David, Moore, Anthony, Meljanac, Corrine, Kumar, Carrie, Zhao, Jennifer, Rosser, Marco, Brotto, Mark L, Johnson, Ziyue, Liu, Michael J, Wacker, Lynda, Bonewald
Publikováno v:
Aging. 15:308-352
Frailty is the hallmark of aging that can be delayed with exercise. The present studies were initiated based on the hypothesis that long-term voluntary wheel running (VWR) in female mice from 12 to 18 or 22 months of age would have beneficial effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2712f002b1c8546d97866f7ccf100f0
https://doi.org/10.18632/aging.204390
https://doi.org/10.18632/aging.204390
Autor:
Mark L. Johnson, Jay Schulkin
A dialogue between contemporary neuroscience and John Dewey's seminal philosophical work Experience and Nature, exploring how the bodily roots of human meaning, selfhood, and values provide wisdom for living. The intersection of cognitive science and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b92eb78864749ba5f13a71eef0212f0b
https://doi.org/10.7551/mitpress/14840.001.0001
https://doi.org/10.7551/mitpress/14840.001.0001
Autor:
Tarak Srivastava, Robert E. Garola, Jianping Zhou, Varun C. Boinpelly, Lakshmi Priya, Mohammed Farhan Ali, Mohammad H. Rezaiekhaligh, Daniel P. Heruth, Jan Novak, Uri S. Alon, Trupti Joshi, Yuexu Jiang, Ellen T. McCarthy, Virginia J. Savin, Mark L. Johnson, Ram Sharma, Mukut Sharma
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 36(10)
Increased fluid-flow shear stress (FFSS) contributes to hyperfiltration-induced podocyte and glomerular injury resulting in progression of chronic kidney disease (CKD). We reported that increased FFSS in vitro and in vivo upregulates PGE2 receptor EP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b19ca974830c3a0fa17e955d4051ce
https://pubmed.ncbi.nlm.nih.gov/36125047
https://pubmed.ncbi.nlm.nih.gov/36125047
Autor:
Nuria Lara-Castillo, JoAnna M. Scott, Hammad Mumtaz, Thiagarajan Ganesh, Mark L. Johnson, Mark T. Begonia, Mark Dallas
Publikováno v:
Aging (Albany NY)
We examined the changes in mechanical strain response of male and female mouse tibia and ulna, using axial compression tests, to assess age-related changes in tibiae and ulnae by a non-contact strain measurement technique called the digital image cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a017f45db6d1715d33cf6667265dfb4d
https://doi.org/10.18632/aging.202350
https://doi.org/10.18632/aging.202350
Osteocyte Wnt/β-catenin pathway activation upon mechanical loading is altered in ovariectomized mice
Autor:
Mark L. Johnson, Nuria Lara-Castillo, Thiagarajan Ganesh, JoAnna M. Scott, Erica Jackson, Mark Dallas, Mohammed P. Akhter
Publikováno v:
Bone Reports
Bone Reports, Vol 15, Iss, Pp 101129-(2021)
Bone Reports, Vol 15, Iss, Pp 101129-(2021)
Estrogen levels decline in both sexes with age, but more dramatically in females. Activation of the Wnt/β-catenin signaling pathway is central to the regulation of bone mass accrual and maintenance and in response to mechanical loading. Using the ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0981c9c9cb705aafa734377f239f7b
http://europepmc.org/articles/PMC8455641
http://europepmc.org/articles/PMC8455641