Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Mark KuKuruga"'
Autor:
Robert J. Dorosky, Jeremy E. Schreier, Stephanie L. Lola, Rosa L. Sava, Michael P. Coryell, Adovi Akue, Mark KuKuruga, Paul E. Carlson, Sheila M. Dreher-Lesnick, Scott Stibitz
Publikováno v:
AMB Express, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Nanobodies are highly specific binding domains derived from naturally occurring single chain camelid antibodies. Live biotherapeutic products (LBPs) are biological products containing preparations of live organisms, such as Lactobacillus, th
Externí odkaz:
https://doaj.org/article/7cd372ca8a2e40b3a7ac94c9591b6358
Autor:
Andrew M Lewis, Gideon Foseh, Wei Tu, Keith Peden, Adovi Akue, Mark KuKuruga, Daniel Rotroff, Gladys Lewis, Ilya Mazo, Steven R Bauer
Publikováno v:
PLoS ONE, Vol 18, Iss 12, p e0293406 (2023)
The AGMK1-9T7 cell line has been used to study neoplasia in tissue culture. By passage in cell culture, these cells evolved to become tumorigenic and metastatic in immunodeficient mice at passage 40. Of the 20 x 106 kidney cells originally plated, le
Externí odkaz:
https://doaj.org/article/de997a3a85884fda8da535cf8cfeb3e0
Autor:
Parna Bhattacharya, Sreenivas Gannavaram, Nevien Ismail, Ankit Saxena, Pradeep K. Dagur, Adovi Akue, Mark KuKuruga, Hira L. Nakhasi
Publikováno v:
Pathogens, Vol 12, Iss 4, p 534 (2023)
No human vaccine is available for visceral leishmaniasis (VL). Live attenuated centrin gene-deleted L. donovani (LdCen−/−) parasite vaccine has been shown to induce robust innate immunity and provide protection in animal models. Toll-like recepto
Externí odkaz:
https://doaj.org/article/ce954f59d47649aeac64fc072e4e623b
Autor:
Miranda S Oakley, Joanna K Chorazeczewski, Maya Aleshnick, Vivek Anantharaman, Victoria Majam, Bhavna Chawla, Timothy G Myers, Qin Su, Winter A Okoth, Kazuyo Takeda, Adovi Akue, Mark KuKuruga, L Aravind, Sanjai Kumar
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0201043 (2018)
Macrophages express a wide array of invariant receptors that facilitate host defense and mediate pathogenesis during pathogen invasion. We report on a novel population of CD11bhighCD14+F4/80+ macrophages that express TCRβ. This population expands dr
Externí odkaz:
https://doaj.org/article/d11403876389432dbbf5a9e4209c03f2
Autor:
Zhao-Hua Zhou, Margaret M. Cortese, Jia-Long Fang, Robert Wood, Donna S. Hummell, Kimberly A. Risma, Allison E. Norton, Mark KuKuruga, Susan Kirshner, Ronald L. Rabin, Cyrus Agarabi, Mary A. Staat, Natasha Halasa, Russell E. Ware, Anna Stahl, Maureen McMahon, Peter Browning, Panagiotis Maniatis, Shanna Bolcen, Kathryn M. Edwards, John R. Su, Sai Dharmarajan, Richard Forshee, Karen R. Broder, Steven Anderson, Steven Kozlowski
BackgroundThe mechanism for anaphylaxis following mRNA COVID-19 vaccination has been widely debated; understanding this serious adverse event is important for future vaccines of similar design. A mechanism proposed is type I hypersensitivity (i.e., I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff339813a34daee1822c1fe92408594
https://doi.org/10.1101/2023.04.11.23288372
https://doi.org/10.1101/2023.04.11.23288372
Autor:
Winter A. Okoth, Mark KuKuruga, Joanna K. Chorazeczewski, Adovi Akue, Maya Aleshnick, Regina Kurapova, Victoria Majam, Sanjai Kumar, Miranda S. Oakley
Recent studies have demonstrated that a subpopulation of neutrophils express the TCRαβ combinatorial immunoreceptor in humans and mice. Here, we report that a Plasmodium berghei ANKA murine malaria infection induces expansion of TCRβ expressing CD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb4d5b81a5b2496cdee3bcac3294ab8
https://europepmc.org/articles/PMC6013678/
https://europepmc.org/articles/PMC6013678/
Autor:
Miranda S Oakley, Joanna Chorazeczewski, Victoria Majam, Bhavna Chawla, Maya Aleshnick, Kazuyo Takeda, Adovi Akue, Mark KuKuruga, Sanjai Kumar
Publikováno v:
The Journal of Immunology. 198:57.5-57.5
Macrophages, a component of the innate immune system, are equipped with a wide array of invariant receptors that facilitate the host defense against invading pathogens via phagocytosis and the release of inflammatory cytokines, and help maintain tiss
Autor:
Mark M. Zalupski, Awtar Krishan, Cheppail Ramachandran, David R. Lucas, James R. Ryan, Mark Kukuruga, Hiroshi Kunikane
Publikováno v:
Cytometry. 30:197-203
Twenty-two fresh surgical specimens of human sarcomas (soft tissue and bone) from 20 patients were analyzed by flow cytometry for the expression of drug resistance-related P-glycoprotein (P-gp) and cellular daunorubicin (DNR) accumulation with or wit
Publikováno v:
Blood. 88:472-478
Increasing evidence especially stemming from peripheral blood progenitor transplantation studies points to a possible biologic difference between mobilized blood and bone marrow progenitor cells. The objective of this study was to compare the in situ
Publikováno v:
Cytometry. 26:40-46
Up to 60% of patients with clinically localized prostate cancer will relapse despite potentially curative local treatment. Current staging tests have been limited in adequately identifying individual patients who are at a high risk for future relapse