Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mark Kin Fai Ma"'
Autor:
Eunice Yuen Ting Lau, Jessica Lo, Bowie Yik Ling Cheng, Mark Kin Fai Ma, Joyce Man Fong Lee, Johnson Kai Yu Ng, Stella Chai, Chi Ho Lin, Suk Ying Tsang, Stephanie Ma, Irene Oi Lin Ng, Terence Kin Wah Lee
Publikováno v:
Cell Reports, Vol 15, Iss 6, Pp 1175-1189 (2016)
Like normal stem cells, tumor-initiating cells (T-ICs) are regulated extrinsically within the tumor microenvironment. Because HCC develops primarily in the context of cirrhosis, in which there is an enrichment of activated fibroblasts, we hypothesize
Externí odkaz:
https://doaj.org/article/3cdc6d5ccfb249248e8b45a87e42a838
Autor:
Irene Oi-Lin Ng, Lily Kwan Wai Cheng, Mark Kin Fai Ma, Terence Kin Wah Lee, Eunice Yuen Ting Lau, Doris Hoi Wing Leung, Regina Cheuk-Lam Lo, Stephanie Ma, John A. Copland, Nicole Pui Yu Ho, Jin Ding, Jessica Lo, Chi Ho Lin
Publikováno v:
Journal of hepatology. 67(5)
Background & Aims We investigated the functional role and clinical significance of stearoyl-CoA desaturase-1 ( SCD1 ) mediated endoplasmic reticulum (ER) stress in regulating liver tumor-initiating cells (T-ICs) and sorafenib resistance, with the aim
Autor:
Irene Oi-Lin Ng, Bowie Yik Ling Cheng, Patrick Ling, Eunice Yuen Ting Lau, Regina Cheuk-Lam Lo, Rachel Hiu Ha Ching, Mark Kin Fai Ma, Terence Kin Wah Lee, Joyce Man-Fong Lee
Publikováno v:
Oncotarget
Hepatocellular carcinoma (HCC) is frequently complicated by the occurrence of intrahepatic and extrahepatic metastases, leading to poor prognosis. To improve the prognosis for HCC patients, there is an urgent need to understand the molecular mechanis
Autor:
Irene Oi-Lin Ng, Vincent Chi Ho Cheung, Francis Tak Yuk So, Jessica Lo, Rachel Hiu Ha Ching, Mark Kin Fai Ma, Ping Lu, Bowie Yik Ling Cheng, Eunice Yuen Ting Lau, Vera S. F. Chan, Terence Kin Wah Lee
Publikováno v:
Liver international : official journal of the International Association for the Study of the Liver. 36(5)
Background & Aims Hepatocellular carcinoma (HCC) is often associated with metastasis and recurrence leading to a poor prognosis. Therefore, development of novel treatment regimens is urgently needed to improve the survival of HCC patients. In this st
Autor:
Mark Kin Fai Ma, Jessica Lo, Irene Oi-Lin Ng, Rachel Hiu Ha Ching, Eunice Yuen Ting Lau, Bowie Yik Ling Cheng, Terence Kin Wah Lee
Publikováno v:
Hepatology (Baltimore, Md.). 62(2)
Sorafenib is a new standard treatment for patients with advanced hepatocellular carcinoma (HCC). However, the survival benefit of this treatment is modest, partly owing to drug resistance. Recent evidence has demonstrated the existence of tumor-initi
Autor:
Stephanie Ma, Joyce Man-Fong Lee, Stella Chai, Chi Ho Lin, Terence Kin Wah Lee, Suk Ying Tsang, Irene Oi-Lin Ng, Eunice Yuen Ting Lau, Mark Kin Fai Ma, Jessica Lo, Johnson Kai Yu Ng, Bowie Yik Ling Cheng
Publikováno v:
Cell Reports, Vol 15, Iss 6, Pp 1175-1189 (2016)
SummaryLike normal stem cells, tumor-initiating cells (T-ICs) are regulated extrinsically within the tumor microenvironment. Because HCC develops primarily in the context of cirrhosis, in which there is an enrichment of activated fibroblasts, we hypo