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pro vyhledávání: '"Mark Killick"'
Publikováno v:
Retrovirology, Vol 16, Iss 1, Pp 1-12 (2019)
Retrovirology
Retrovirology
The existing repertoire of HIV-1 patient derived broadly neutralising antibodies (bNAbs) that target the HIV-1 envelope glycoprotein (Env) present numerous and exciting opportunities for immune-based therapeutic and preventative strategies against HI
Publikováno v:
AIDS Research and Human Retroviruses. 30:1001-1005
The tight bottleneck during HIV-1 transmission generally results in only a single virus variant being transmitted. Investigation of the HIV-1 envelope glycoprotein (Env) can identify vulnerabilities of transmitting viruses that can be targeted by vac
Autor:
Nichole Cerutti, Maria A. Papathanasopoulos, Alexio Capovilla, Vinesh Jugnarain, Mark Killick
Publikováno v:
Journal of Biological Chemistry. 289:10455-10465
Human CD4 is a membrane-bound glycoprotein expressed on the surface of certain leukocytes, where it plays a key role in the activation of immunostimulatory T cells and acts as the primary receptor for human immunodeficiency virus (HIV) glycoprotein (
Publikováno v:
Biochimica et biophysica acta. 1860(9)
Background CD4 is a glycoprotein expressed on the surfaces of certain immune cells. On lymphocytes, an important function of CD4 is to co-engage Major Histocompatibility Complex (MHC) molecules with the T Cell Receptor (TCR), a process that is essent
Autor:
Mark Killick, Barry V. Mendelow, Wendy Stevens, Maria A. Papathanasopoulos, Alexio Capovilla, Nichole Cerutti, Makobetsa Khati, Grant Bredell Napier
Publikováno v:
Journal of Biological Chemistry. 285:25743-25752
HIV-1 enters cells via interaction between the trimeric envelope (Env) glycoprotein gp120/gp41 and the host cell surface receptor molecule CD4. The requirement of CD4 for viral entry has rationalized the development of recombinant CD4-based proteins
Autor:
Mark Killick, Michelle L. Grant, Alexio Capovilla, Nichole Cerutti, Maria A. Papathanasopoulos
Publikováno v:
Vaccine. 33(46)
The ability to induce a broadly neutralizing antibody (bNAb) response following vaccination is regarded as a crucial aspect in developing an effective vaccine against human immunodeficiency virus type 1 (HIV-1). The bNAbs target the HIV-1 envelope gl
Autor:
Mark Killick
Publikováno v:
British Journalism Review. 13:91-94
Publikováno v:
Retrovirology
Retrovirology, Vol 9, Iss Suppl 2, p P21 (2012)
Retrovirology, Vol 9, Iss Suppl 2, p P21 (2012)
Background The ability to induce a broadly neutralizing antibody (bNAb) response following vaccination is regarded as a crucial aspect in developing an effective HIV-1 vaccine. This study describes the design and construction of a subtype C founder v
Autor:
Mark Killick
Publikováno v:
Sunday Business (United Kingdom). 09/17/2000.