Výsledky vyhledávání - "Mark Kheng Chuan Tan"

Impact of selective immune-cell depletion on growth of Mycobacterium tuberculosis (Mtb) in a whole-blood bactericidal activity (WBA) assay

Autor: Nicholas I. Paton, Mark Kheng Chuan Tan, Rupangi Verma, Paul Edward Hutchinson, Benjamin Chaik Meng Yeo, Gail B Cross, Qingshu Lu

Publikováno v: PLoS ONE, Vol 14, Iss 5, p e0216616 (2019)
PLoS ONE

We investigated the contribution of host immune cells to bacterial killing in a whole-blood bactericidal activity (WBA) assay, an ex vivo model used to test efficacy of drugs against mycobacterium tuberculosis (Mtb). We performed WBA assays with immu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df070bb5ad27711652ce808758af9a6d
https://doi.org/10.1371/journal.pone.0216616

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Regiospecific solid-phase strategy to N7-substituted purines and its application to 8-azapurines and [I]-condensed purines

Autor: Yulin Lam, Mark Kheng Chuan Tan, Han Fu

Publikováno v: Journal of combinatorial chemistry. 9(5)

A highly regioselective and traceless solid-phase route to 1,7,8-trisubstituted purines has been developed. This methodology could be extended to the preparation of 8-azapurines and [i]-condensed purines. A representative set of 17 purines, azapurine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3d9e7194ca9a2e6e626fc7b4cd8df41
https://pubmed.ncbi.nlm.nih.gov/17688325

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Akademický článek

Regiospecific Solid-Phase Strategy to N7-Substituted Purines and Its Application to 8-Azapurines and i-Condensed Purines.

Autor: Han Fu¹, Mark Kheng Chuan Tan¹, Yulin Lam¹

Publikováno v: Journal of Combinatorial Chemistry. Sep2007, Vol. 9 Issue 5, p804-810. 7p.

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