Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mark K. Clements"'
Cloning and expression of bovine p47-phoxand p67-phox: comparison with the human and murine homologs
Autor:
Peggy L. Bunger, Angela R. Davis, Mark K. Clements, Katherine A. Gauss, Daniel W. Siemsen, Steve D. Swain, Mark T. Quinn
Publikováno v:
Journal of Leukocyte Biology. 67:63-72
Neutrophils play an essential role in bovine cellular host defense, and compromised leukocyte function has been linked to the development of respiratory and mucosal infections. During the host defense process, neutrophils migrate into infected tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c95ff28a02366af7c592054129e0a84
https://doi.org/10.1002/jlb.67.1.63
https://doi.org/10.1002/jlb.67.1.63
Publikováno v:
Cancer Chemotherapy and Pharmacology. 40:475-483
Purpose: To assess parameters that might determine resistance to the topoisomerase I inhibitor, camptothecin (CPT), the sensitivities of three established human breast cancer cell lines (ER−) and of normal bovine endothelial cells to CPT in the fre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3df66753f445f4a2b1c602fd977c70
https://doi.org/10.1007/s002800050690
https://doi.org/10.1007/s002800050690
Publikováno v:
Anti-Cancer Drugs. 7:851-857
We have reported earlier that camptothecin (CPT) incorporated into multilamelar liposomes of appropriate lipid composition displayed effective anti-tumor activity with minimal host toxicity in a nude mouse model xenographed with the human breast carc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce3ad209f5b3976dff151a89c8fd56ee
https://doi.org/10.1097/00001813-199611000-00006
https://doi.org/10.1097/00001813-199611000-00006
Publikováno v:
International journal of oncology. 17(5)
Previous research has shown synergistic growth inhibition between UCN-01 and camptothecin (CPT) in tumor cells with mutant p53 versus tumor cells with wild-type p53. To determine the possible role of p53 in this drug combination, we tested the hypoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60f54e3e89a5793d30b0529a16e5d1e
https://pubmed.ncbi.nlm.nih.gov/11029511
https://pubmed.ncbi.nlm.nih.gov/11029511
Publikováno v:
Veterinary immunology and immunopathology. 74(3-4)
GTPases of the Rho family play important roles in human leukocyte signal transduction pathways; however, little is known about the function of these proteins in bovine cells. In the present studies, we isolated molecular clones of bovine Rac1, Rac2,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e4a1f6650315d89c90f8c9b9fa28df3
https://pubmed.ncbi.nlm.nih.gov/10802295
https://pubmed.ncbi.nlm.nih.gov/10802295
Publikováno v:
Cancer chemotherapy and pharmacology. 45(3)
Purpose: To determine the ability of UCN-01 to abrogate the cell cycle arrest induced by camptothecin (CPT) in tumor cells that lack p53 function, and therefore enhance the cytotoxicity of CPT in these cells in relation to normal cells with wild-type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50be1f4e958c03d4898c26e635a5310f
https://pubmed.ncbi.nlm.nih.gov/10663644
https://pubmed.ncbi.nlm.nih.gov/10663644
Publikováno v:
Cancer chemotherapy and pharmacology. 44(5)
Purpose: To determine the inhibitory nature of sublethal doses of camptothecin (CPT) and topotecan (TPT) treatments on normal human endothelial cells in vitro, as well as the in vivo antiangiogenic activity as compared to another antiangiogenic compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e88e63a322461410b1aee10a74f7fc
https://pubmed.ncbi.nlm.nih.gov/10501915
https://pubmed.ncbi.nlm.nih.gov/10501915
Publikováno v:
Anti-cancer drugs. 6(3)
The purpose of this study was to determine whether the observed synergistic interaction between cisplatin and valinomycin (VM) in human ovarian carcinoma is the result of mitochondrial DNA (mtDNA) damage. A polymerase chain reaction (PCR)-based metho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be8b44098744b7194295d775449fc995
https://pubmed.ncbi.nlm.nih.gov/7670138
https://pubmed.ncbi.nlm.nih.gov/7670138