Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mark J. van der Woerd"'
Publikováno v:
Journal of the American Statistical Association. 114:39-47
Small-angle X-ray scattering (SAXS) is a technique that yields low-resolution structural information of biological macromolecules by exposing a large ensemble of molecules in solution to a powerful...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d761c975ed5cabd2ee65121300d247ec
https://doi.org/10.1080/01621459.2017.1408467
https://doi.org/10.1080/01621459.2017.1408467
Publikováno v:
J Synchrotron Radiat
Xylose isomerase (XI) is an industrially important metalloprotein studied for decades. Its reaction mechanism has been postulated to involve movement of the catalytic metal cofactor to several different conformations. Here, a dose-dependent approach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f06ff9865469f8810e76938d5dfd36b
https://ora.ox.ac.uk/objects/uuid:408c9beb-bf49-40a2-8afe-6ae343a69f07
https://ora.ox.ac.uk/objects/uuid:408c9beb-bf49-40a2-8afe-6ae343a69f07
Publikováno v:
Journal of Computational and Graphical Statistics. 25:225-245
Variational approximations provide fast, deterministic alternatives to Markov Chain Monte Carlo for Bayesian inference on the parameters of complex, hierarchical models. Variational approximations are often limited in practicality in the absence of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f969be54ce3d949419e0fa43e3fb744f
https://doi.org/10.1080/10618600.2014.983642
https://doi.org/10.1080/10618600.2014.983642
Publikováno v:
Bayesian Anal. 12, no. 1 (2017), 113-133
The general projected normal distribution is a simple and intuitive model for directional data in any dimension: a multivariate normal random vector divided by its length is the projection of that vector onto the surface of the unit hypersphere. Obse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f718fbe0a2af990f830f6026b5bf54ce
http://projecteuclid.org/euclid.ba/1453211962
http://projecteuclid.org/euclid.ba/1453211962
Autor:
Zhong Ren, Russell A. Judge, Dean A. A. Myles, Parthapratim Munshi, Edward H. Snell, Flora Meilleur, Mark J. van der Woerd
Publikováno v:
Acta Crystallographica Section D Biological Crystallography. 70:414-420
Ketol-isomerases catalyze the reversible isomerization between aldoses and ketoses. D-Xylose isomerase carries out the first reaction in the catabolism of D-xylose, but is also able to convert D-glucose to D-fructose. The first step of the reaction i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aadc584890ea8024df433eecb932cb0
https://doi.org/10.1107/s1399004713029684
https://doi.org/10.1107/s1399004713029684
Publikováno v:
Journal of Time Series Analysis. 33:704-717
Small-angle X-ray scattering (SAXS) is a technique for obtaining low-resolution structural information about biological macromolecules, by exposing a dilute solution to a high-intensity X-ray beam and capturing the resulting scattering pattern on a t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9cfb54bc803600ba57562cea115b67d
https://doi.org/10.1111/j.1467-9892.2011.00779.x
https://doi.org/10.1111/j.1467-9892.2011.00779.x
Autor:
Ha T. Pham, Ana Carreras-González, Devinder Kaur, David Albesa-Jové, Francis Schaeffer, Sonia Lopez-Fernandez, Patrick J. Brennan, Mary Jackson, Saioa Urresti, Petra Gest, Mark J. van der Woerd, Pedro M. Alzari, Marcelo E. Guerin
Publikováno v:
Journal of Biological Chemistry; Vol 287
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2012, 287 (29), pp.24649-24661. ⟨10.1074/jbc.M112.368191⟩
Journal of Biological Chemistry, 2012, 287 (29), pp.24649-24661. ⟨10.1074/jbc.M112.368191⟩
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2012, 287 (29), pp.24649-24661. ⟨10.1074/jbc.M112.368191⟩
Journal of Biological Chemistry, 2012, 287 (29), pp.24649-24661. ⟨10.1074/jbc.M112.368191⟩
International audience; Considerable progress has been made in recent years in our understanding of the structural basis of glycosyl transfer. Yet the nature and relevance of the conformational changes associated with substrate recognition and cataly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5869feb1e8dc8707b3ff9cf7c450c221
Publikováno v:
Nucleic Acids Research
MeCP2 is a highly abundant chromatin architectural protein with key roles in post-natal brain development in humans. Mutations in MeCP2 are associated with Rett syndrome, the main cause of mental retardation in girls. Structural information on the in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19e0ffc657ca3e274b75c1dfac295e60
https://doi.org/10.1093/nar/gkr005
https://doi.org/10.1093/nar/gkr005
Publikováno v:
Journal of Molecular Biology. 395:983-994
The enzyme poly(ADP-ribose) polymerase-1 (PARP-1) is a global monitor of chromatin structure and DNA damage repair. PARP-1 binds to nucleosomes and poly(ADP-ribosylates) histones and several chromatin-associated factors to expose specific DNA sequenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de445821f6e9b1d40d1a71a73b1618a0
https://doi.org/10.1016/j.jmb.2009.11.062
https://doi.org/10.1016/j.jmb.2009.11.062
Autor:
Mary Jackson, Pedro M. Alzari, David Giganti, Marcelo E. Guerin, Jana Korduláková, Mark J. van der Woerd, Francis Schaeffer, Alain Chaffotte, Petra Gest
Publikováno v:
Journal of Biological Chemistry. 284:21613-21625
Phosphatidyl-myo-inositol mannosyltransferase A (PimA) is an essential glycosyltransferase (GT) involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIMs), which are key components of the mycobacterial cell envelope. PimA is the para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92fc2f5d9fb45c6b69ba332f9129557f
https://doi.org/10.1074/jbc.m109.003947
https://doi.org/10.1074/jbc.m109.003947