Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Mark J. van Raaij"'
Autor:
Abrar Senhaji-Kacha, Mireia Bernabéu-Gimeno, Pilar Domingo-Calap, John Jairo Aguilera-Correa, Mateo Seoane-Blanco, Sara Otaegi-Ugartemendia, Mark J. van Raaij, Jaime Esteban, Meritxell García-Quintanilla
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
The increase of antibiotic-resistant bacteria has become a global health emergency and the need to explore alternative therapeutic options arises. Phage therapy uses bacteriophages to target specific bacterial strains. Phages are highly specific and
Externí odkaz:
https://doaj.org/article/8c11897a0c9c42599b584b763b015bb2
Publikováno v:
IUCrJ, Vol 10, Iss 4, Pp 377-379 (2023)
This editorial acknowledges the transformative impact of new machine-learning methods, such as the use of AlphaFold, but also makes the case for the continuing need for experimental structural biology.
Externí odkaz:
https://doaj.org/article/08110045186d4245962bb14f4413bfb6
Autor:
Ángela Rodríguez, María Maneiro, Emilio Lence, José M. Otero, Mark J. van Raaij, Paul Thompson, Alastair R. Hawkins, Concepción González-Bello
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Irreversible inhibition of the enzyme type I dehydroquinase (DHQ1), a promising target for anti-virulence drug development, has been explored by enhancing the electrophilicity of specific positions of the ligand towards covalent lysine modification.
Externí odkaz:
https://doaj.org/article/cd7d202952bc4340a777bcf1a88518ac
Autor:
Edward N. Baker, Charles S. Bond, Elspeth F. Garman, Janet Newman, Randy J. Read, Mark J. van Raaij
Publikováno v:
IUCrJ, Vol 9, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/0128d5448fcd4b7bb2c12851760a7418
Autor:
Carmen San Martín, Mark J. van Raaij
Publikováno v:
Virology Journal, Vol 15, Iss 1, Pp 1-6 (2018)
Abstract Background During the last two decades, structural biology analyses have shown that viruses infecting hosts far apart in evolution share similar architectural features, prompting a new virus classification based on structural lineages. Until
Externí odkaz:
https://doaj.org/article/0ab464e9f3e14a6e95a94274da76e881
Autor:
John R. Helliwell, Wladek Minor, Manfred S. Weiss, Elspeth F. Garman, Randy J. Read, Janet Newman, Mark J. van Raaij, Janos Hajdu, Edward N. Baker
Publikováno v:
IUCrJ, Vol 6, Iss 3, Pp 341-343 (2019)
Externí odkaz:
https://doaj.org/article/abdf3270f7b24633a2f882b6f9229ab7
Autor:
Carmela Garcia-Doval, José R. Castón, Daniel Luque, Meritxell Granell, José M. Otero, Antonio L. Llamas-Saiz, Madalena Renouard, Pascale Boulanger, Mark J. van Raaij
Publikováno v:
Viruses, Vol 7, Iss 12, Pp 6424-6440 (2015)
Bacteriophage T5, a Siphovirus belonging to the order Caudovirales, has a flexible, three-fold symmetric tail, to which three L-shaped fibres are attached. These fibres recognize oligo-mannose units on the bacterial cell surface prior to infection an
Externí odkaz:
https://doaj.org/article/feeb526dc0a44e799b17aaa3e54d1352
Autor:
Vincenzo Pennone, Marta Sanz-Gaitero, Paula O’Connor, Aidan Coffey, Kieran Jordan, Mark J. van Raaij, Olivia McAuliffe
Publikováno v:
Viruses, Vol 11, Iss 8, p 722 (2019)
Listeria monocytogenes is a ubiquitous Gram-positive bacterium that is a major concern for food business operators because of its pathogenicity and ability to form biofilms in food production environments. Bacteriophages (phages) have been evaluated
Externí odkaz:
https://doaj.org/article/2d004c30ff134d81b2fc501fa4951124
Autor:
Imke H. E. Korf, Jan P. Meier-Kolthoff, Evelien M. Adriaenssens, Andrew M. Kropinski, Manfred Nimtz, Manfred Rohde, Mark J. van Raaij, Johannes Wittmann
Publikováno v:
Viruses, Vol 11, Iss 5, p 454 (2019)
The aim of this study was to gain further insight into the diversity of Escherichia coli phages followed by enhanced work on taxonomic issues in that field. Therefore, we present the genomic characterization and taxonomic classification of 50 bacteri
Externí odkaz:
https://doaj.org/article/d4f6e10739c045c69753009b15b2a738
Publikováno v:
Viruses, Vol 9, Iss 7, p 168 (2017)
Long tail fibers of bacteriophage T4 are formed by proteins gp34, gp35, gp36, and gp37, with gp34 located at the phage-proximal end and gp37 at the phage-distal, receptor-binding end. We have solved the structure of the carboxy-terminal region of gp3
Externí odkaz:
https://doaj.org/article/471783b7756d47cbb53d15f2f5ca9d16