Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Mark J. W. Hanssen"'
Autor:
Yong Chen, Joschka J. Buyel, Mark J. W. Hanssen, Franziska Siegel, Ruping Pan, Jennifer Naumann, Michael Schell, Anouk van der Lans, Christian Schlein, Holger Froehlich, Joerg Heeren, Kirsi A. Virtanen, Wouter van Marken Lichtenbelt, Alexander Pfeifer
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Exosomes are RNA-containing lipid vesicles with roles in inter-tissue crosstalk. Here the authors show that exosome release from brown adipocytes is increased upon thermogenic activation, both in vitro and in vivo, and demonstrate that serum levels o
Externí odkaz:
https://doaj.org/article/a5a3002cb6614c3fa06055d50ee9c5fe
Autor:
Natasha M. Appelman-Dijkstra, Kimberly J. Nahon, Mark J. W. Hanssen, Mariëtte R. Boon, Ingrid M. Jazet, Laura G.M. Janssen, Patrick C.N. Rensen, Hanneke Reinders, Wouter D. van Marken Lichtenbelt, Sander Kooijman, Andrea D. van Dam
Publikováno v:
Diabetes & Metabolism Journal, Vol 44, Iss 2, Pp 326-335 (2020)
Diabetes & Metabolism Journal
Diabetes and Metabolism Journal, 44(2), 326-335. KOREAN DIABETES ASSOC
Diabetes and Metabolism Journal, 44(2):e54, 326-335. Korean Diabetes Association
Diabetes & Metabolism Journal
Diabetes and Metabolism Journal, 44(2), 326-335. KOREAN DIABETES ASSOC
Diabetes and Metabolism Journal, 44(2):e54, 326-335. Korean Diabetes Association
BACKGROUND: South Asians generally have an unfavourable metabolic phenotype compared with white Caucasians, including central obesity and insulin resistance. The Wnt protein family interacts with insulin signaling, and impaired Wnt signaling is assoc
Autor:
Kimberly J. Nahon, Ingrid M. Jazet, Mark J. W. Hanssen, Boudewijn Brans, Jan B. van Klinken, Cindy J. M. Hülsman, Patrick C.N. Rensen, Charlotte Bakker, Gert Schaart, Joris Hoeks, Wouter D. van Marken Lichtenbelt, Mariëtte R. Boon, Bas Havekes
Publikováno v:
Diabetologia
Diabetologia, 62(1), 112-122. Springer Verlag
Diabetologia, 62(1), 112-122
Diabetologia, 62(1), 112-122. Springer, Cham
Diabetologia, 62(1), 112-122. Springer Verlag
Diabetologia, 62(1), 112-122
Diabetologia, 62(1), 112-122. Springer, Cham
Aims/hypothesis Individuals of South Asian origin are at increased risk of developing type 2 diabetes mellitus and associated comorbidities compared with Europids. Disturbances in energy metabolism may contribute to this increased risk. Skeletal musc
Autor:
Tom H. M. Ottenhoff, Mark J. W. Hanssen, Patrick C.N. Rensen, Hetty C M Sips, Andrea D. van Dam, Mariëlle C. Haks, Cindy J. M. Hülsman, Ingrid M. Jazet, Wouter D. van Marken Lichtenbelt, Robin van Eenige, Edwin Quinten, Mariëtte R. Boon
Publikováno v:
Diabetologia, 60(12), 2525-2528
Diabetologia, 60(12), 2525-2528. Springer, Cham
Diabetologia, 60(12), 2525-2528. Springer, Cham
Autor:
Joris Hoeks, Mark J. W. Hanssen, Boudewijn Brans, Anouk A.J.J. van der Lans, Felix M. Mottaghy, Wouter D. van Marken Lichtenbelt, Kelly M.C. Jardon, Gert Schaart, Patrick Schrauwen
Publikováno v:
Diabetes, 65(5), 1179-1189. American Diabetes Association
Recruitment of brown adipose tissue (BAT) has emerged as a potential tool to combat obesity and associated metabolic complications. Short-term cold acclimation has been shown not only to enhance the presence and activity of BAT in lean humans but als
Autor:
Mariëtte R. Boon, Mark J. W. Hanssen, Thomas Hankemeier, Vasudev Kantae, Patrick C.N. Rensen, Wouter D. van Marken Lichtenbelt, Kimberly J. Nahon, Amy C. Harms, Ingrid M. Jazet, Mario van der Stelt, Roy den Haan
Publikováno v:
Obesity, 26(8), 1332-1337. Wiley
Obesity
Obesity, 26(8), 1332-1337
Obesity
Obesity, 26(8), 1332-1337
OBJECTIVE The study aimed to investigate whether markers of endocannabinoid signaling differed between men with overweight of South Asian and white Caucasian descent. METHODS We included South Asian (n = 10) and white Caucasian (n = 10) men with over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0795117cf954ee625f8c8d72bf086ad
https://hdl.handle.net/1887/75532
https://hdl.handle.net/1887/75532
Autor:
Wouter D. van Marken Lichtenbelt, Maarten J. Vosselman, Mark J. W. Hanssen, Boudewijn Brans, Anouk A.J.J. van der Lans
Publikováno v:
The Journal of Physiological Sciences
Journal of Physiological Sciences, 66(1), 77-83. Springer
JOURNAL OF PHYSIOLOGICAL SCIENCES
Journal of Physiological Sciences, 66(1), 77-83. Springer
JOURNAL OF PHYSIOLOGICAL SCIENCES
The 'gold standard' for measuring brown adipose tissue (BAT) in humans is [(18)F]FDG-PET/CT-imaging. With this technique subjects are exposed to ionizing radiation and are therefore limited in the number of scans that can be performed. We investigate
Autor:
Felix M. Mottaghy, Wouter D. van Marken Lichtenbelt, Joris Hoeks, Mark V. Boekschoten, Mark J. W. Hanssen, Bas Havekes, Jose J. van den Driessche, Boudewijn Brans, Johanna A. Jörgensen, Gert Schaart, Sander Kersten, Patrick Schrauwen, Matthijs K. C. Hesselink, Anouk A.J.J. van der Lans
Publikováno v:
Nature Medicine 21 (2015) 8
Nature Medicine, 21(8), 863-865. Nature Publishing Group
Nature Medicine, 21(8), 863-865
Nature Medicine, 21(8), 863-865. Nature Publishing Group
Nature Medicine, 21(8), 863-865
Cold exposure may be a potential therapy for diabetes by increasing brown adipose tissue (BAT) mass and activity. Here we report that 10 d of cold acclimation (14-15 degrees C) increased peripheral insulin sensitivity by approximately 43% in eight ty
Autor:
Franziska Siegel, Jennifer Naumann, Anouk A.J.J. van der Lans, Yong Chen, Holger Froehlich, Mark J. W. Hanssen, Christian Schlein, Joschka J. Buyel, Kirsi A. Virtanen, Wouter D. van Marken Lichtenbelt, Ruping Pan, Alexander Pfeifer, Joerg Heeren, Michael J. Schell
Publikováno v:
Nature Communications, 7:11420. Nature Publishing Group
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Brown adipose tissue (BAT) dissipates energy and its activity correlates with leanness in human adults. 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography coupled with computer tomography (PET/CT) is still the standard for measuring BAT ac
Autor:
Mark J. W. Hanssen, Patrick Schrauwen, Anne Gemmink, Felix M. Mottaghy, Wouter D. van Marken Lichtenbelt, Joris Hoeks, Roel Wierts, Boudewijn Brans
Publikováno v:
Diabetologia, 58(3), 586-595. Springer, Cham
Human brown adipose tissue (BAT) has recently emerged as a potential target in the treatment of type 2 diabetes, owing to its capacity to actively clear glucose from the circulation—at least upon cold exposure. The effects of insulin resistance on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7149144f52b2767da45d0f3d8cedd2e6
https://cris.maastrichtuniversity.nl/en/publications/02023462-90d9-41b0-85da-cbac594a6205
https://cris.maastrichtuniversity.nl/en/publications/02023462-90d9-41b0-85da-cbac594a6205