Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mark J. Pekker"'
Publikováno v:
Therapeutic Advances in Endocrinology and Metabolism, Vol 14 (2023)
Background: Thyroid hormones are controlled by the hypothalamic–pituitary–thyroid (HPT) axis through a complex network of regulatory loops, involving the hormones TRH, TSH, FT4, and FT3. The relationship between TSH and FT4 is widely used for dia
Externí odkaz:
https://doaj.org/article/944d026a2fab4c45b525bb41f59166b0
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Endocrine regulation in the hypothalamic-pituitary-thyroid (HPT) axis is orchestrated by physiological circuits which integrate multiple internal and external influences. Essentially, it provides either of the two responses to overt biological challe
Externí odkaz:
https://doaj.org/article/a6382158f0cf4200a150a2f0d15ee32c
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 11 (2022)
Background Lewy body diseases (LBDs) feature deficiency of the sympathetic neurotransmitter norepinephrine in the left ventricular myocardium and sympathetic intra‐neuronal deposition of the protein alpha‐synuclein (αS). LBDs therefore are auton
Externí odkaz:
https://doaj.org/article/5e9c96f483ef41969ba45b198c85b9d2
Publikováno v:
Frontiers in endocrinology. 13
Endocrine regulation in the hypothalamic-pituitary-thyroid (HPT) axis is orchestrated by physiological circuits which integrate multiple internal and external influences. Essentially, it provides either of the two responses to overt biological challe
Publikováno v:
European Journal of Clinical Investigation. 50
Background Defined by thyroid-pituitary feedback control, clinical diagnosis of hypothyroidism and hyperthyroidism has become synonymous with TSH measurement. We combined in silico analysis and in vivo data to explore the central influences on thyroi
Publikováno v:
JCI insight. 5
BACKGROUND Lewy body diseases, a family of aging-related neurodegenerative disorders, entail loss of the catecholamine dopamine in the nigrostriatal system and equally severe deficiency of the closely related catecholamine norepinephrine in the heart
Publikováno v:
SSRN Electronic Journal.
Background: Lewy body diseases such as Parkinson disease (PD) are well known to be characterized by nigrostriatal dopamine deficiency. These disorders also entail drastic (95-99%) myocardial depletion of the sympathetic neurotransmitter norepinephrin