Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mark J. Leech"'
Autor:
Pedro J. Rocha, Mark J. Leech
Publikováno v:
Revista Colombiana de Biotecnología, Vol 4, Iss 2 (2002)
Cathmnthus roseus es una planta medicinal productora de varios alcaloides indol terpenoides (AIT) con actividad farmacológica. Empleando plantas y cultivos celulares de C. roseus la ruta biosintética de AIT ha sido determinada, además, un consider
Externí odkaz:
https://doaj.org/article/0372e550f80c4a25b9e1ba9efc09a576
Autor:
Frédérique Hilliou, Patrícia Duarte, Maria Manuela Ribeiro Costa, Mark J. Leech, Mariana Sottomayor, Johan Memelink, Luis Gustavo Pereira, Iolanda Almeida, Alfonso Ros Barceló
Publikováno v:
Plant Physiology
Plant Physiology, American Society of Plant Biologists, 2008, 146 (2), pp.403-417. ⟨10.1104/pp.107.107060⟩
Plant Physiology, American Society of Plant Biologists, 2008, 146 (2), pp.403-417. ⟨10.1104/pp.107.107060⟩
Catharanthus roseus produces low levels of two dimeric terpenoid indole alkaloids, vinblastine and vincristine, which are widely used in cancer chemotherapy. The dimerization reaction leading to alpha-3',4'-anhydrovinblastine is a key regulatory step
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e95ea40677bc7fd263689d4932f365ef
https://doi.org/10.1104/pp.107.107060
https://doi.org/10.1104/pp.107.107060
Autor:
Paul Christou, Adrian J. Parr, Olaf Stenzel, Birgit Dräger, Nicholas J. Walton, Mark J. Leech, Pedro Rocha
Publikováno v:
Plant Science. 162:905-913
The cDNAs from Hyoscyamus niger , encoding two enzymes of tropane-alkaloid biosynthesis, tropinone reductase I (TR-I) and hyoscyamine-6b-hydroxylase (H6H), have been simultaneously introduced into Nicotiana tabacum using particle bombardment and expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8507e8680997b9422a57edfac0b0b946
https://doi.org/10.1016/s0168-9452(02)00033-x
https://doi.org/10.1016/s0168-9452(02)00033-x
Publikováno v:
Plant Cell Reports. 20:808-813
We describe an efficient process for the regeneration of Lonicera tatarica plants from cultured stem sections. Induction of multiple shoots was achieved directly from cultured stem cuttings. The highest regeneration rate was achieved an Gamborg's B5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d447dda80fdecfba4c0f3f5d8d7b74e3
https://doi.org/10.1007/s00299-001-0415-y
https://doi.org/10.1007/s00299-001-0415-y
Autor:
Stephen Rawsthorne, Trevor L. Wang, Mark J. Leech, Lynda Turner, Kathleen M. Baird, Susan A. Johnson, Cliff L. Hedley, Peter L. Jack, Sabine L. Schreck, Ruth M. Mould, Christopher John Harrison
Publikováno v:
Plant Physiology. 122:1187-1192
Two cDNA clones were isolated from pea (Pisum sativum L.) and their deduced amino acid sequences shown to have significant homology to phosphoglucomutases from eukaryotic and prokaryotic sources. The longer cDNA contained a putative transit-peptide-e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62805ed26b7e88385742a0bee484d324
https://doi.org/10.1104/pp.122.4.1187
https://doi.org/10.1104/pp.122.4.1187
Publikováno v:
Transgenic Research. 9:163-168
We report an efficient whole plant transformation system for Hyoscyamus muticus, an important medicinal plant of the Solanaceous family. We developed a system using a plasmid carrying the nptII and gusA genes, which was delivered into leaf explants b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb5d7b657264d5ccb5d955d967e26aca
https://doi.org/10.1023/a:1008912330067
https://doi.org/10.1023/a:1008912330067
Publikováno v:
Plant Science. 140:179-188
We have developed an efficient direct DNA transfer procedure for the facile engineering of Catharanthus roseus cell cultures. Particle bombardment of callus derived from leaf material permitted rapid selection and establishment of transgenic cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::734841493d103d83b5bf4ed6f28366e6
https://doi.org/10.1016/s0168-9452(98)00225-8
https://doi.org/10.1016/s0168-9452(98)00225-8
Publikováno v:
Proceedings of the National Academy of Sciences. 95:7203-7208
Organization of transgenes in rice transformed through direct DNA transfer strongly suggests a two-phase integration mechanism. In the “preintegration” phase, transforming plasmid molecules (either intact or partial) are spliced together. This gi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85b0d18ab5c2a9ac56c6c90d547a661a
https://doi.org/10.1073/pnas.95.12.7203
https://doi.org/10.1073/pnas.95.12.7203
Autor:
H. Liu, Barbara Worland, Mark J. Leech, Philippe Vain, M. Beavis, H. Atkinson, M. C. Clarke, Ajay Kohli, John W. Snape, Paul Christou, G. Richard
Publikováno v:
Theoretical and Applied Genetics. 96:266-271
We have used a genotype-independent transformation system involving particle gun bombardment of immature embryos to genetically engineer rice as part of a programme to develop resistance to nematodes. Efficient tissue culture, regeneration, DNA deliv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d1021a3d3f5a0b8ab87015687245d75
https://doi.org/10.1007/s001220050735
https://doi.org/10.1007/s001220050735
Publikováno v:
Plant Molecular Biology. 38:765-774
We have created a population of transgenic tobacco plants carrying cDNAs encoding two consecutive enzymes from early stages in monoterpenoid alkaloid biosynthesis in Catharanthus roseus. The cDNAs, encoding tryptophan decarboxylase (tdc) and strictos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9bbb104a03815767a413abd8ea27484
https://doi.org/10.1023/a:1006000229229
https://doi.org/10.1023/a:1006000229229