Výsledky vyhledávání - "Mark J. Kazmierczak"

Extreme value theory in analysis of differential expression in microarrays where either only up- or down-regulated genes are relevant or expected

Autor: Yrjö T. Gröhn, Mark J. Kazmierczak, Martin Wiedmann, Martin T. Wells, Sarita Raengpradub, Renata Ivanek

Publikováno v: Genetics Research. 90:347-361

SummaryWe propose an empirical Bayes method based on the extreme value theory (EVT) (BE) for the analysis of data from spotted microarrays where the interest of the investigator (e.g. to identify up-regulated gene markers of a disease) or the design

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12471c6d6bffe7d8e3b4e62c5d72a42d
https://doi.org/10.1017/s0016672308009427

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Contributions of Listeria monocytogenes σ B and PrfA to expression of virulence and stress response genes during extra- and intracellular growth

Autor: Mark J. Kazmierczak, Martin Wiedmann, Kathryn J. Boor

Publikováno v: Microbiology. 152:1827-1838

Listeria monocytogenes σBand PrfA are pleiotropic regulators of stress response and virulence gene expression. Quantitative RT-PCR (qRT-PCR) was used to measure transcript levels ofσB- and PrfA-dependent genes in exponential-phaseL. monocytogeneswi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01220db2207fa240aeddd8aaaa2cb6e4
https://doi.org/10.1099/mic.0.28758-0

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Alternative Sigma Factors and Their Roles in Bacterial Virulence

Autor: Mark J. Kazmierczak, Kathryn J. Boor, Martin Wiedmann

Publikováno v: Microbiology and Molecular Biology Reviews. 69:527-543

SUMMARY Sigma factors provide promoter recognition specificity to RNA polymerase holoenzyme, contribute to DNA strand separation, and then dissociate from the core enzyme following transcription initiation. As the regulon of a single sigma factor can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd4c7c0c45efe0df165cb2ff71d80e5
https://doi.org/10.1128/mmbr.69.4.527-543.2005

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Listeria monocytogenes σB Regulates Stress Response and Virulence Functions

Autor: Sharon C. Mithoe, Mark J. Kazmierczak, Martin Wiedmann, Kathryn J. Boor

While the stress-responsive alternative sigma factor σBhas been identified in different species ofBacillus,Listeria, andStaphylococcus, theσBregulon has been extensively characterized only inB. subtilis.We combined biocomputing and microarray-based

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a83143827fae0ec6a496a60e97083c6
https://europepmc.org/articles/PMC193959/

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